Majocchi’s Granuloma by Trichophytum rubrum in a kidney transplant patient - A case report

Introduction: Trichophytum rubrum is a filamentous fungus, with worldwide distribution, that usually causes superficial infections of skin and nails, namely tinea pedis, tinea corporis, tinea cruris and onychomycosis. Rarely, severe dermatophytosis can occur, presenting as deep dermatophytosis, Majocchi’s Granuloma or extensive dermatophytosis. Objectives and Methods: Case report of Majocchi’s Granuloma in a kidney transplant patient. Results: A case of a 55-year-old woman who underwent a kidney transplant 7 months before, under immunosuppressive therapy with tacrolimus and mycophenolate mofetil. She attended a Dermatology consultation to clarify skin lesions that appeared 6 months earlier. The skin exam revealed hard and painful plaque lesions on both legs, with an ulcer on the left leg lesion, violaceous papular lesions on the dorsum of the left foot and toes and a hard consistency nodule on the left leg. Some of the toe nails presented dystrophy or onycholysis. The patient denied any previous trauma or contact with plants or soil. Biopsies of lesions of the left leg and foot dorsum where sent for histology and mycological culture and toe nails for mycological culture. The histological examinations showed, in the reticular dermis and reaching the hypodermis, suppurative granulomas with multinucleated giant cells and areas of necrosis. PAS (Periodic Acid- Schiff) and GMS (Grocott’s Methenamine Silver) staining revealed multiple spores and septate hypha within the granulomas but not in the stratum corneum. No remnants of hair follicles where found. Culture of skin biopsies were positive for Tricophytum rubrum but nails´ culture was negative. Identification was further confirmed by sequencing of ITS region of ribosomal DNA (GenBank accession number MK967277). Oral Itraconazole 100mg bid and topic Sertoconazole where initiated. The patient was observed one month after and reported general malaise, tiredness, exertional dyspnea, whitish stools and increased abdominal volume. The physician chose to discontinue itraconazole and initiate oral terbinafine 250mg id. After two months on oral terbinafine, there was regression of the legs´ and left foot lesions with ulcer healing and disappearance of the left leg nodule. Conclusion: Diagnosis of deeper dermatophytosis is difficult, in part because there is no specific clinical presentation and, in many cases, it is even polymorphic. However, especially in patients with immunodeficiency, this hypothesis should be weighed. Confirmation is achieved by finding hyphae compatible with dermatophytes in the dermis and a positive culture for a dermatophyte. Treatment should include systemic antifungal agents, to which topical medication may be associated. Multiple therapeutic regimens have been proposed, but randomized trials or large case series are lacking. Antifungal therapy should be continued until the lesions are completely resolved. Surgical treatment has been reported as an option for highly localized lesions.info:eu-repo/semantics/publishedVersio

Reliable teleportation in trapped ions

We study a method for the implementation of a reliable teleportation protocol (theoretically, 100% of success) of internal states in trapped ions. The generation of the quantum channel (any of four Bell states) may be done respecting technical limitations on individual addressing and without claiming the Lamb-Dicke regime. An adequate Bell analyzer, that transforms unitarily the Bell basis into a completely disentangled one, is considered. Probable sources of error and fidelity estimations of the teleportation process are studied. Finally, we discuss experimental issues, proposing a scenario in which the present scheme could be implemented.Comment: 8 Latex pages with five (ps,eps) figures included (EPJ style also included). Accepted for publication in European Physical Journal

Analysis of process variables via CFD to evaluate the performance of a FCC riser

Feedstock conversion and yield products are studied through a 3D model simulating the main reactor of the fluid catalytic cracking (FCC) process. Computational fluid dynamic (CFD) is used with Eulerian-Eulerian approach to predict the fluid catalytic cracking behavior. The model considers 12 lumps with catalyst deactivation by coke and poisoning by alkaline nitrides and polycyclic aromatic adsorption to estimate the kinetic behavior which, starting from a given feedstock, produces several cracking products. Different feedstock compositions are considered. The model is compared with sampling data at industrial operation conditions. The simulation model is able to represent accurately the products behavior for the different operating conditions considered. All the conditions considered were solved using a solver ANSYS CFX 14.0. The different operation process variables and hydrodynamic effects of the industrial riser of a fluid catalytic cracking (FCC) are evaluated. Predictions from the model are shown and comparison with experimental conversion and yields products are presented; recommendations are drawn to establish the conditions to obtain higher product yields in the industrial process

Asymmetric band diagrams in photonic crystals with a spontaneous nonreciprocal response

We study the propagation of electromagnetic waves in layered photonic crystals formed by materials with a spontaneous nonreciprocal response, such as Tellegen (axion) media or topological insulators. Surprisingly, it is proven that stratified Tellegen photonic crystals that break simultaneously the space inversion and time-reversal symmetries have always symmetric dispersion diagrams. Interestingly, we show that by combining chiral and nonreciprocal materials the photonic band diagrams can exhibit a spectral asymmetry such that omega(k) not equal omega(-k). Furthermore, it is demonstrated that in some conditions two juxtaposed Tellegen medium layers have an electromagnetic response analogous to that of a biased ferrite slab.info:eu-repo/semantics/publishedVersio

Interação genótipo-ambiente em bovinos: revisão de estudos no Brasil.

bitstream/item/31742/1/Doc-365.pdfVersão eletrônica disponível em papel

Test Case 4: dual band transmit-array

In this report a numerical solution for the dual band transmit-array challegenge proposed for the WORKSHOP EM-ISAE 2018 (test case nº 4) is presented. The numerical results are compared with the measurements of the corresponding prototype (see Figure 1). More details about the design and fabrication processes of the dual band TA can be found in [1]. To perform the corresponding full-wave simulations was quite challenging, mainly due to the large volume occupied by the antenna (comprising the feed and lens) and the fine subwavelength details of the unit cells that populate the TA. In fact, we did not had at that time sufficient memory to perform the full-wave simulation of the complete antenna (feed+lens). In this workshop we detailed the developed approach used to conduct the full-wave analysis of the TA within our available computational resources.info:eu-repo/semantics/acceptedVersio

COST Action TU 1406 quality specifications for roadway bridges (BridgeSpec)

Roadway bridges, being one of the most critical road infrastructures components, require regular maintenance actions. Therefore, it becomes important to define strategies to maximize societal benefits, derived from the investment made in these assets. Consequently, this investment should be planned, effectively managed and technically supported by appropriate management systems, supported in quality control plans. For this purpose, authorities need to produce an asset management plan which should, not only define the goals to be achieved by exploiting the roadway bridge network, but also identify the investment needs and priorities based on a life cycle cost criteria. Additionally, a proper condition assessment of these assets must be conducted to support the decision-making process regarding their preservation. A COST Action recently started in Europe with the aim of standardizing the establishment of quality control plans for roadway bridges. This paper describes this Action and, particularly, its most recent developments. MaintenanceThis article is based upon work from COST Action TU-1406, Quality specifications for roadway bridges, standardization at a European level (BridgeSpec), supported by COST (European Cooperation in Science and Technology)

Perfilhamento de cultivares de Brachiaria Brizantha e Panicum Maximum em fase inicial de implantação.

bitstream/item/89804/1/BOP-24.pd