1,301 research outputs found

    Composite Ground Modification System: Vibroreplacement and Dynamic Compaction, Salt Lake County Detention Center, Utah

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    The site for a new Adult Detention Center currently under construction in Salt Lake City, Utah, is underlain by loose sands and soft clayey lake deposits. Due to bearing capacity, static settlement, and liquefaction concerns, a hybrid ground improvement program consisting of both dynamic compaction and vibroreplacement was implemented. Stone columns were concentrated under spread and wall footings; dynamic compaction was performed over the whole site. A comprehensive quality assurance/ quality control program was executed, with a significant number of cone penetration tests, standard penetration tests, 10 plate load tests, and deceleration readings taken with an accelerometer mounted on the dynamic compaction weight. This large body of data enabled the authors to assess the effectiveness of the ground improvement program, as well as analyze the results of the experimental deceleration readings

    Robust Intrapulmonary CD8 T Cell Responses and Protection with an Attenuated N1L Deleted Vaccinia Virus

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    BACKGROUND: Vaccinia viruses have been used as a model for viral disease and as a protective live vaccine. METHODOLOGY AND PRINCIPAL FINDINGS: We investigated the immunogenicity of an attenuated strain of vaccinia virus engineered to inactivate the N1L gene (vGK5). Using the intranasal route, this recombinant virus was 2 logs less virulent compared to the wildtype VACV-WR. Infection by the intranasal, intraperitoneal, and tail scarification routes resulted in the robust induction of cytolytic virus-specific CD8 T cells in the spleens and the lungs. VACV-specific antibodies were also detected in the sera of mice infected 3-5 months prior with the attenuated vGK5 virus. Finally, mice immunized with vGK5 were significantly protected when challenged with a lethal dose of VACV-WR. CONCLUSIONS: These results indicate that the attenuated vGK5 virus protects against subsequent infection and suggest that the N1L protein limits the strength of the early antiviral CD8 T cell response following respiratory infection

    Influence of incubation time on the vibration and mechanic properties of mycowood

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    The goal of the current study was to investigate the physical and mechanical properties of mycowood as a high quality tone-wood, obtained from Norway spruce by treatment of the white rot fungus Physisporinus vitreus as a function of the treatment time. In focus was the stiffness to weight ratio, which is often considered a main criterion for tone-wood selection. The vibro-mechanical properties were tested by non-destructive methods. The change of color and density were also measured after 4-12 months of fungal incubation. Density decreased up to 5% after 12 months of fungal treatment. Sound velocity was measured in small size specimens by means of the free-free vibration approach, while in large specimens the air-coupled ultrasound method was applied. The two techniques gave similar results and indicated that the sound velocity decreased in mycowood. Internal damping was increased in mycowood to a higher extent than the reduction in the specific modulus of elasticity (E/ρ) and thus the sound velocity in the material. The sound velocity was decreasing with increasing incubation times and scattering of data with this regard was larger in the transversal than in the longitudinal direction. The sound radiation coefficient and the characteristic impedance were enhanced in mycowood and its color was more brownish and richer in tone

    Effects of dilution on the hardness and residual stresses in multipass steel weldments

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    A thermal-metallurgical-mechanical model was developed to study the effects of dilution in each weld pass for multipass gas tungsten arc and submerged arc welding in low alloy steel (i.e. SA508) plates. Hardness distributions and residual stresses were measured on the transverse sections perpendicular to the welding direction of the manufactured weldments. The predicted hardness and residual stresses were compared with the measurement data and shown to be reasonably accurate. The results showed that dilution can significantly affect both the hardness and the residual stress field in the weld metal. It was found that, for the base and filler materials used, increased dilution led to greater weld-metal hardness and reduced the magnitude of tensile stress or promoted compressive stress in the as-deposited and reheated weld metals. This mechanical behaviour is associated with the tendency for diluted weld metal to experience delayed austenite decomposition, owing to the high hardenability of SA508 steel relative to the filler materials used. Although dilution is irrelevant for the hardness of the base material and its transformation products adjacent to the weld metal, it affected the full-field residual stresses via the equilibrium interaction between the stresses in the base and weld metal

    BVRI Light Curves for 29 Type Ia Supernovae

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    BVRI light curves are presented for 27 Type Ia supernovae discovered during the course of the Calan/Tololo Survey and for two other SNe Ia observed during the same period. Estimates of the maximum light magnitudes in the B, V, and I bands and the initial decline rate parameter m15(B) are also given.Comment: 17 pages, figures and tables are not included (contact first author if needed), to appear in the Astronomical Journa

    Through-Thickness Residual Stress Profiles in Austenitic Stainless Steel Welds: A Combined Experimental and Prediction Study

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    Economic and safe management of nuclear plant components relies on accurate prediction of welding-induced residual stresses. In this study, the distribution of residual stress through the thickness of austenitic stainless steel welds has been measured using neutron diffraction and the contour method. The measured data are used to validate residual stress profiles predicted by an artificial neural network approach (ANN) as a function of welding heat input and geometry. Maximum tensile stresses with magnitude close to the yield strength of the material were observed near the weld cap in both axial and hoop direction of the welds. Significant scatter of more than 200 MPa was found within the residual stress measurements at the weld center line and are associated with the geometry and welding conditions of individual weld passes. The ANN prediction is developed in an attempt to effectively quantify this phenomenon of ‘innate scatter’ and to learn the non-linear patterns in the weld residual stress profiles. Furthermore, the efficacy of the ANN method for defining through-thickness residual stress profiles in welds for application in structural integrity assessments is evaluated

    Wastewater monitoring for detection of public health markers during the COVID-19 pandemic: Near-source monitoring of schools in England over an academic year

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    BACKGROUND: Schools are high-risk settings for infectious disease transmission. Wastewater monitoring for infectious diseases has been used to identify and mitigate outbreaks in many near-source settings during the COVID-19 pandemic, including universities and hospitals but less is known about the technology when applied for school health protection. This study aimed to implement a wastewater surveillance system to detect SARS-CoV-2 and other public health markers from wastewater in schools in England. METHODS: A total of 855 wastewater samples were collected from 16 schools (10 primary, 5 secondary and 1 post-16 and further education) over 10 months of school term time. Wastewater was analysed for SARS-CoV-2 genomic copies of N1 and E genes by RT-qPCR. A subset of wastewater samples was sent for genomic sequencing, enabling determination of the presence of SARS-CoV-2 and emergence of variant(s) contributing to COVID-19 infections within schools. In total, >280 microbial pathogens and >1200 AMR genes were screened using RT-qPCR and metagenomics to consider the utility of these additional targets to further inform on health threats within the schools. RESULTS: We report on wastewater-based surveillance for COVID-19 within English primary, secondary and further education schools over a full academic year (October 2020 to July 2021). The highest positivity rate (80.4%) was observed in the week commencing 30th November 2020 during the emergence of the Alpha variant, indicating most schools contained people who were shedding the virus. There was high SARS-CoV-2 amplicon concentration (up to 9.2x106 GC/L) detected over the summer term (8th June - 6th July 2021) during Delta variant prevalence. The summer increase of SARS-CoV-2 in school wastewater was reflected in age-specific clinical COVID-19 cases. Alpha variant and Delta variant were identified in the wastewater by sequencing of samples collected from December to March and June to July, respectively. Lead/lag analysis between SARS-CoV-2 concentrations in school and WWTP data sets show a maximum correlation between the two-time series when school data are lagged by two weeks. Furthermore, wastewater sample enrichment coupled with metagenomic sequencing and rapid informatics enabled the detection of other clinically relevant viral and bacterial pathogens and AMR. CONCLUSIONS: Passive wastewater monitoring surveillance in schools can identify cases of COVID-19. Samples can be sequenced to monitor for emerging and current variants of concern at the resolution of school catchments. Wastewater based monitoring for SARS-CoV-2 is a useful tool for SARS-CoV-2 passive surveillance and could be applied for case identification and containment, and mitigation in schools and other congregate settings with high risks of transmission. Wastewater monitoring enables public health authorities to develop targeted prevention and education programmes for hygiene measures within undertested communities across a broad range of use cases

    Crop Updates 2000 - Cereals part 2

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    This session covers twenty papers from different authors: DISEASE 1. Forecasting aphid and virus risk in cereals, Debbie Thackray, Jenny Hawkes and Roger Jones, Agriculture Western Australia and Centre for Legumes in Mediterranean Agriculture 2. Cereal Diagnostics, Dominie Wright, Agriculture Western Australia 3. The economic returns from spraying for leaf rust in the central wheatbelt in 1999, Peter Carlton, Trials Coordinator, Elders Limited 4. Impact and Management of Yellow Spot and Leaf Rust in the Northern Agricultural Region, Jat Bhathal and Robert Loughman, Agriculture Western Australia 5. Leaf disease management in wheat and barley in the southern agricultural region, K. Jayasena, R. Loughman and J. Majewski, Agriculture Western Australia 6. Root nematode update, R. Loughman1, S. Kelly1, G. Holloway2, N. Venn1 and D. Diepeveen1 1 Agriculture Western Australia, 2Agriculture Victoria WHEAT AGRONOMY 7. Small Grain Screenings in wheat - the agronomic issues, Brenda Shackley, Agriculture Western Australia, 8. Response of New Wheat Varieties to Seed Rate and applied Nitrogen in the North, Darshan Sharma and Wal Anderson, Agriculture Western Australia 9. Seen vigour in wheat, Darshan Sharma and Wal Anderson, Agriculture Western Australia 10. Influence of the Time of Sowing on New Wheat Varieties in the North, Darshan Sharma and Wal Anderson, Agriculture Western Australia 11, Wheat performance in a high disease season on the South Coast. 1. Disease and grain quality on the Esperance sandplain, Mohammad Amjad, Vanessa Dooley and Wal Anderson, Agriculture Western Australia 12. Wheat performance in a high disease season on the South Coast. 2. Leaf area, disease and yield at Gibson and Salmon Gums, Mohammad Amjad, Vanessa Dooley and Wal Anderson, Agriculture Western Australia 13. Agronomic Evaluation of Wheat in the Central Wheatbelt of Western Australia, Peter Burgess and Ashley Bacon, Agritech Crop Research 14. Mechanisms influencing grain susceptibility to black point in wheat, Frances Hoyle, University of Western Australia and Agriculture Western Australia 15. Improving paddock productivity using renovation cropping techniques on heavier soils, Frances Hoyle, Agriculture Western Australia 16. Improving paddock productivity using renovation cropping techniques on sandplain soils, Frances Hoyle and Keith Devenish, Agriculture Western Australia 17. Increasing profit - Is it possible using high input package approach for cereal production? M. Appelbee, IAMA Agri Services 18. Improving wheat yield, soil physical and chemical fertility by a package of deep ripping, gypsum and complete nutrients, M.A. Hamza and W.K. Anderson, Agriculture Western Australia 19. Organic Wheat - Production System Guidelines, Steven McCoy, Centre for New Industries Development 20. Durum wheat obtains a premium over bread wheat, Steven Penny, Agriculture Western Australi
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