93,967 research outputs found
Novel Computational Approach to Obtain Contact Angles: Application to Carbon Capture and Storage
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The Galois group of a stable homotopy theory
To a "stable homotopy theory" (a presentable, symmetric monoidal stable
-category), we naturally associate a category of finite \'etale algebra
objects and, using Grothendieck's categorical machine, a profinite group that
we call the Galois group. We then calculate the Galois groups in several
examples. For instance, we show that the Galois group of the periodic
-algebra of topological modular forms is trivial and that
the Galois group of -local stable homotopy theory is an extended version
of the Morava stabilizer group. We also describe the Galois group of the stable
module category of a finite group. A fundamental idea throughout is the purely
categorical notion of a "descendable" algebra object and an associated analog
of faithfully flat descent in this context.Comment: 93 pages. To appear in Advances in Mathematic
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Understanding Disease Heterogeneity and Patient Characteristics in Patients with Amyotrophic Lateral Sclerosis (ALS)
Background: Amytrophic lateral sclerosis (ALS) is a fatal neurologic disease that is projected to double in worldwide incidence in the next 20 years. The heterogenic nature of the disease and relatively limited research data, compared to non-rare diseases, have made it difficult for clinician researchers to alter the course of the disease within the short life expectancy after symptom onset. Method: This was a mixed-method retrospective review and live sampling study using three distinct data sources. Retrospective data was abstracted from the electronic medical record systems for a select group of ALS patients seen at the University of California, Irvine Neuromuscular Center (UCI NMC). Additional retrospective datasets curated by the Pooled Resources Open-Access Clinical Trials (PRO-ACT) database were also analyzed. Observational data was collected using a 9-item survey developed on Google Forms and disseminated through the ALS Association Golden West Chapter. The items measured symptom onset, diagnostic journey, and patient demographics.Results: The analyses confirmed current reports of higher disease incidence in Caucasian populations, usually comprising at least 60% of each dataset. The gender prevalence towards males was only observed in the PRO-ACT dataset. There was also a difference in mean age between PRO-ACT (56 years), UCI (61 years), and Online Questionnaire respondents (66 years). Discussion: Ultimately retrospective data analyses were limited by substantial missing, not at random data. Large data repositories can bridge the gap between non-rare and rare disease research, but only with robust and methodologic data collection across all participating sites
News, Documentary and Advocacy Journalism
This chapter examines how alternative models of journalism are emerging to counter the news values associated with the so-called mainstream media - news values, which are increasingly criticised for serving only the interests of the political and economic elite. In particular, this chapter looks at advocacy journalism, which focuses on a shift away from objectivity towards the arguably more ethical practice of attachment. The neutral and detached reporter, who remains outside of events and reports only facts, becomes a campaigner immersed in a story to call for and foster real social change
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