642 research outputs found
Quaternary faulting in the New Madrid seismic zone in southernmost Illinois
U.S. Geological Survey, Department of the Interior, National Earthquake Hazards Reduction Program Award No. 1434-95-G-2525Ope
A Method to Distinguish Quiescent and Dusty Star-forming Galaxies with Machine Learning
Large photometric surveys provide a rich source of observations of quiescent galaxies, including a surprisingly large population at z > 1. However, identifying large, but clean, samples of quiescent galaxies has proven difficult because of their near-degeneracy with interlopers such as dusty, star-forming galaxies. We describe a new technique for selecting quiescent galaxies based upon t-distributed stochastic neighbor embedding (t-SNE), an unsupervised machine-learning algorithm for dimensionality reduction. This t-SNE selection provides an improvement both over UVJ, removing interlopers that otherwise would pass color selection, and over photometric template fitting, more strongly toward high redshift. Due to the similarity between the colors of high- and low-redshift quiescent galaxies, under our assumptions, t-SNE outperforms template fitting in 63% of trials at redshifts where a large training sample already exists. It also may be able to select quiescent galaxies more efficiently at higher redshifts than the training sample
Groups of Galaxies in the Two Micron All-Sky Redshift Survey
We present the results of applying a percolation algorithm to the initial
release of the Two Micron All-Sky Survey Extended Source Catalog, using
subsequently measured redshifts for almost all of the galaxies with K < 11.25
mag. This group catalog is based on the first near-IR all-sky flux-limited
survey that is complete to |b| = 5 deg. We explore the dependence of the
clustering on the length and velocity scales involved. The paper describes a
group catalog, complete to a limiting redshift of 10,000 km/s, created by
maximizing the number of groups containing 3 or more members. A second catalog
is also presented, created by requiring a minimum density contrast of 80 to
identify groups. We identify known nearby clusters in the catalogs and contrast
the groups identified in the two catalogs. We examine and compare the
properties of the determined groups and verify that the results are consistent
with the UZC-SSRS2 and northern CfA redshift survey group catalogs. The all-sky
nature of the catalog will allow the development of a flow-field model based on
the density field inferred from the estimated cluster masses.Comment: Accepted for publication in ApJ (29 pages including 13 figures). A
version with high-resolution figures is available at
http://www.cfa.harvard.edu/~acrook/preprints
Quaternary faulting in the New Madrid seismic zone in southernmost Illinois
U.S. Geological Survey, Department of the Interior, under USGS award number 1434-95-G-2525Ope
Effect of cancer-associated mutations in the PlexinB1 gene
<p>Abstract</p> <p>Background</p> <p>Semaphorins act as chemotactic cues for cell movement via their transmembrane receptors, plexins. Somatic missense mutations in the plexinB1 gene coupled with overexpression of the protein frequently occur in prostate tumours, indicating a role for plexinB1 in the pathogenesis of prostate cancer.</p> <p>Results</p> <p>Two specific mutations found in prostate cancer enhance RhoD binding and one other mutation results in loss of inhibition of Rac-dependent Pak1 phosphorylation and lamellipodia formation and in impairment of trafficking of plexinB1 to the membrane. None of the three characterised mutations affect PDZRhoGEF binding, RhoA activity, the interaction of plexinB1with the oncogenes ErbB2 or c-Met or ErbB2 phosphorylation. The mutations have the net effect of increasing cell motility by blocking plexinB1-mediated inhibition of Rac while enhancing the interaction with RhoD, an anti-migratory factor.</p> <p>Conclusions</p> <p>PlexinB1 mutations block plexinB1-mediated signalling pathways that inhibit cell motility.</p
The management of tree genetic resources and the livelihoods of rural communities in the tropics: non-timber forest products, smallholder agroforestry practices and tree commodity crops
Products and services provided by trees in forests and farmland support the needs and promote the wellbeing of hundreds of millions of people in the tropics. Value depends on managing both the diversity of tree species present in landscapes and the genetic variation within these species. The benefits from trees and their genetic resources are, however, often not well quantified because trade is frequently outside formal markets, there is a multiplicity of species and ways in which trees are used and managed, and genetic diversity within species is frequently not given proper consideration. We review here what is known about the value of trees to rural communities through considering three production categories: non-timber products harvested from trees in natural and managed forests and woodlands; the various products and services obtained from a wide range of trees planted and/or retained in smallholdersâ agroforestry systems; and the commercial products harvested from cultivated tree commodity crops. Where possible, we focus on the role of intra-specific genetic variation in providing support to livelihoods, and for each of the three production categories we also consider wider conservation and sustainability issues, including the linkages between categories in terms of management. Challenges to âconventional wisdomâ on tree resource use, value and management â such as in the posited links between commercialisation, cultivation and conservation â are highlighted, and constraints and opportunities to maintain and enhance value are described
A classification algorithm for predicting progression from normal cognition to mild cognitive impairment across five cohorts: The preclinical AD consortium
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