Sposoby realizacji zrównoważonego rozwoju w przemyśle

Industry is in the greatest degree responsible for the deteriorated quality of the environment. The holistic approach to production aims at prevention of environmental pollution and wastes. It begins at the stage of project design, through production phase and recycling possibilities. Technical dimension is especially devoted to look for products or technologies which are material-saving, energy-efficient and no-waste. The aim of the article is to present supportive methods for introducing the principle of sustainable development into industrial plants.Przemysł jest w największym stopniu odpowiedzialny za pogarszający się stan środowiska przyrodniczego. Całościowe ujęcie produkcji to współczesna profilaktyka powstawania zanieczyszczeń środowiska i odpadów. Rozpoczyna się ona od pomysłu stworzenia produktu czyli projektowania, poprzez wytwarzanie i możliwości ponownego wykorzystania. Płaszczyzna technologiczna jest więc szczególnym miejscem poszukiwań produktów czy technologii materiałooszczędnych, energooszczędnych i małoodpadowych. Niniejsza praca ma na celu przedstawienie metod wspomagających wprowadzanie zasady zrównoważonego rozwoju do zakładów produkcyjnych

Endometriosis with dyspnea – is it possible?

Dyspnea is defined by American Thoracic Society as a subjective experience of breathing discomfort that consist of qualitatively distinct sensation that vary in intensity. As a pulmonary symptom, it is rarely associated with pathology of the reproductive organs. However, shortness of breath can be the first sign of endometriosis. The entity known as thoracic endometriosis syndrome is a manifestation of endometriosis, within the lung parenchyma or on the diaphram and pleural surface. This includes catamenial pneumothorax, hemothorax, hemoptysis, and pulmonary nodules

Physical activity in prevention and treatment of type 2 diabetes mellitus

Type 2 diabetes in more than 70% of cases is caused by overweight and obesity. In many cases, a proper diet and increased physical activity are effective in the prevention and treatment of insulin resistance and pre-diabetes, which usually prevents the development of the disease. However, the recommendations for physical activity in type 2 diabetics differ from those for healthy people. The paper presents an analysis of recommendations concerning physical activity in the prevention and treatment of type 2 diabetes

History of glucose monitoring: past, present, future

New technologies in diabetes care are developing dynamically in recent years. The article presents a historical outline of the methods of glucose measurement and current and developing glucose monitoring technologies

Cadmium(II) and calcium(II) complexes with N,O-bidentate ligands derived from pyrazinecarboxylic acid

The synthesis and characterization of cad- mium(II) and calcium(II) complexes with N , O -bidentate ligands derived from pyrazinecarboxylic acid (3-hydroxy- 2-quinoxalinecarboxylic acid HL 1 , pyrazine-2-carboxylic acid HL 2 ) are reported. Obtained compounds [Cd(L 1 ) 2 (H 2 O) 2 ](H 2 O) 2 ( 1 ), [Cd(L 2 ) 2 ] n ( 2 ) and [Ca(L 2 ) 2 (H 2 O) 4 ]( 3 ) were studied by elemental analyses, IR, Raman spectros- copy and thermogravimetric methods (TG, DTG, DSC). In addition, the molecular structure of complex 1 has been determined by X-ray single crystal diffraction. Thermal analysis reveals a decomposition process of 1 , 3 complexes in multiple stages. The data obtained from TG and DSC curves for 1 , 3 confirm not only the presence but also the nature of water (crystallization and coordination) and the stoichiometry of the studied metal complexes. The results of thermal studies are in good agreement with their crystal structures. Thermal behavior of complex 2 indicates a single complete decomposition process of the sample. In addition, complex 2 as a coordination polymer is the most stable all of them and the thermal stability of the obtained complexes can be ordered in the following sequence: 1 \ 3 2

The prognostic value of mean platelet volume in cancer patients

Basic hematological indices, such as platelets count (PLT), platelet distribution width (PDW), mean platelet volume (MPV), and plateletcrit (PCT), are readily accessible and commonly tested indicators. As platelets play a significant role in many physiological and patho- logical pathways, the abnormalities in these indices inference about irregularities within the organism, such as homeostatic disorders or inflammation. Recent studies revealed a significant impact of MPV on the course and prediction in different types of neoplasms. This review summarizes the most important studies on the impact of MPV levels on outcome and prognosis in different types of cancer conducted in recent years. MPV levels have a significant impact on the length of progression-free survival (PFS) and overall survival (OS) in many types of solid tumors, such as colorectal carcinoma, gastric cancer, pancreatic cancer, esophageal cancer, non-small cell lung cancer, breast cancer, and thyroid cancer. They also affect the prognosis in some lymphoproliferative diseases, such as diffuse large B-cell lymphoma, acute lymphoblastic leukemia, or primary and secondary myelofibrosis

Analiza efektywności techniki MLPA w inwazyjnej diagnostyce prenatalnej najczęstszych aneuploidii

Cel badania: Ustalenie efektywności metody MLPA (multiplex ligation dependent probe amplification) w prenatalnej diagnostyce najczęściej występujących aneuploidii (chromosomów 21, 18, 13, X oraz Y) oraz porównanie wyników uzyskanych tą metodą z wynikami rutynowych technik prążkowych. Materiał i metoda: Przeprowadzono badanie metodą MLPA z zastosowaniem zestawu sond SALSA MLPA P095 (MRC – Holland) na 195 próbkach DNA wyizolowanego z materiału pochodzącego z inwazyjnych badań prenatalnych wykonanych w Pracowni USG SPSK im. Prof. Orłowskiego od października 2008 r. do lipca 2012 r. u pacjentek o podwyższonym ryzyku aberracji chromosomowych u płodu oraz 5 próbkach materiału po poronieniu indukowanym. Jednocześnie prowadzono hodowle komórkowe i oceniano kariotyp klasyczną metodą cytogenetyczną. Wyniki: Kariotyp oznaczono w 192 badaniach prenatalnych (98,5%; 192/195). W 52 przypadkach (26,8%) stwierdzono nieprawidłowy kariotyp płodu – w większości proste aneuploidie chromosomów 13, 18, 21, X i Y (86,5%, 45/52). Wynik metodą MLPA udało się uzyskać w 180 próbkach DNA z materiału pobranego prenatalnie (92,3 180/195). Bezwzględna czułość i swoistość metody MLPA wyniosła 100%. W dziewięciu próbkach pobranych prenatalnie metodą MLPA nie zidentyfikowano aberracji wykrytych klasyczną metodą prążkową lub FISH. W żadnym z tych przypadków nie było możliwe uzyskanie rzeczywistego wyniku stosowanym zestawem sond. We wszystkich próbkach materiału po poronieniu udało się przeprowadzić reakcję MLPA. Wnioski: MLPA jest skuteczną metodą wykrywania najczęstszych aneuploidii w diagnostyce prenatalnej. Ze względu na małą ilość przeprowadzonych reakcji na materiale po poronieniu, ocena przydatności metody w tych przypadkach wymaga dalszych badań

Novel eight-coordinated Cd(II) complexes with two homologous pyridine alcohols : crystal structure, spectroscopic and thermal properties

Two novel cadmium(II) complexes with homologous pyridine alcohols: [Cd(2-MeOHPy) 2 (NO 3 ) 2 ]( 1 ) and [Cd(2-EtOHPy) 2 (NO 3 ) 2 ]( 2 ) have been prepared and characterized by elemental analysis, X-ray crystallo- graphic studies, spectroscopic (IR, 1 H and 13 C NMR) and thermal properties. IR, NMR and X-ray analysis have confirmed a bidentate fashion of coordination of heteroaromatic alcohols with Cd(II) ions. 2-MeO- HPy bound directly to the central ion by N, O-donor atoms giving five-membered chelate ring but 2- EtOHPy formed less stable six-membered chelate ring. In the complex ( 1 ) and ( 2 ) bidentate nitrate ligands are arranged in cis position for organic ligands. In both cases cadmium(II) ions are eight-coordi- nated and shape of coordination polyhedral can be described as pseudo-dodecahedron (CdN 2 O 6 chromo- phore type). The crystal packing of Cd(II) complexes are stabilized by intermolecular classical hydrogen bonds of O A H O and non-classical C A H O type. In addition, there are p – p stacking interactions between almost parallel-displaced pyridine rings of 2-hydroxymethylpyridine in the two neighbouring complex ( 1 ) molecules but the hydrogen interactions in ( 2 ) are formed by C A H donor group of Py rings and p -electron system of neighbouring one