Solar radiation exposure of shielded air temperature sensors and measurement error evaluation in an urban environment: a preliminary study in Florence, Italy

Particularly in summer, thermal conditions in urban areas are influenced by solar radiation and human health can be strongly affected by the higher temperature regime increased by the Urban Heat Island effect (UHI). Many studies have been carried out to estimate the temperature distribution in urban areas and some of these use or are based on data collected by meteorological instruments placed within the cities. At microscale, temperature collected by sensors can be influenced by the underlying surface characteristics and the closeness to warm surfaces. The aim of this study is to investigate how different exposure to solar radiation can affect air temperature measurement in streets and gardens. The study was carried out on two different areas in Florence during summer 2007. Shielded air temperature sensors were placed in a street of a high density built-up area and in a green area. Each area was monitored by two sensors, sited in different solar radiation exposure: one in a sunny area and the other in a shaded one. A preliminary data analysis showed a difference in every site between the air temperature values collected by the two sensors especially from the morning to the afternoon. The relationship between air temperature differences and synoptic meteorological conditions were also analyzed. In conclusion, the solar radiation exposure of a monitoring station is an important parameter that must be considered both during the instruments siting and the analysis of data collected by sensors previously placed. The result of this study shows that during particular synoptic conditions, data collected by the two sensors of the same area can be different

Remote digital monitoring during the retention phase of orthodontic treatment: A prospective feasibility study

Objective: To evaluate if a remote digital monitoring system added at the end of orthodontic treatment could positively influence the retention phase by reducing the occurrence of misfit of removable appliances, number of emergency appointments (EA), and orthodontic relapse. Methods: Twenty-seven patients who completed active orthodontic treatment were divided into the study and control groups. In addition to the standard chairside follow-up appointments at month 1 (T1), month 3 (T2), month 6 (T3), the study group patients were monitored using Dental Monitoring® with monthly intra-oral scans. Occurrence of misfit of removable retainers, number of EAs, and intercanine width change were recorded for both groups. Differences in EAs and retainer fit were assessed using the chi-square test. Intra-group and inter-group differences in the intercanine width were assessed with Friedman test and Mann–Whitney U test, respectively (α = 0.05). Results: The study group showed a significantly lower occurrence of misfit of removable retainers (p = 0.027) compared to the control group. No significant inter-and intra-group difference was found in the EAs and intercanine width change at each time-point. Conclusions: Integrating remote monitoring systems, such as Dental Monitoring®, to the retention phase of the orthodontic treatment may lower the occurrence of misfit of removable retainers. However, a small sample size and a short observation period limit the strength of this evidence. These preliminary results tentatively suggest that remote monitoring technologies may be beneficial, especially during the COVID-19 pandemic, when the regularity of in-office visits might be disrupted

Developing and validating a new multi‐dimensional scale for anti‐social behavior in a higher education setting

Abstract: The purpose of this research is to construct and validate a multi-dimensional scale of Anti-social Behaviour (hereafter ASB) in a Western higher education context (i.e. USA). To achieve this, four studies, each with a different sample, were performed. Study 1 (n = 150) followed an exploratory design to generate a pool of potential items measuring ASB. Study 2 (n = 254) explored the dimensionality of the items produced in Study 1 using Exploratory Factor Analysis (EFA) and reliability measures. Study 3 (n = 654) confirmed the factorial structure from Study 2 and assessed the measurement model invariance using structural equation modelling (SEM). Finally, Study 4 (n = 287) assessed the predictive validity of the ASB measure through testing a hypothetical path model linking ASB to narcissism and Machiavellianism via an SEM procedure. In total, our research findings conclude that the ASB measurement model is a two-factor multi-dimensional structure comprising: Interpersonal Antagonistic Behaviour (six items) as well as Indirect Distractive Behaviour (four items). The research and practical implications for universities are thereafter discussed

UTCI field measurements in an urban park in Florence (Italy)

The aim of this study is to evaluate human thermal comfort in different green area settings in the city of Florence by using the Universal Thermal Climate Index (UTCI). Field measurements of air temperature, solar radiation, relative humidity, wind speed and black globe thermometer were collected during hot summer days in various parts of Cascine Park, the biggest urban park in Florence (Italy). UTCI was evaluated over different surfaces (asphalt, gravel and grass) completely exposed to the sun or shaded by a large lime tree (Tilia × europaea). The results showed strong differences in UTCI values depending on the exposure to tree shade, while no significant difference was found among ground-cover materials when all surfaces were equally exposed to solar radiation. Future studies are needed to investigate the microclimatic effects of different tree species on UTCI

Functional Tricuspid Regurgitation Repair at the time of Left-Sided Valve Surgery. the Impact on the Cardiac Rehabilitation Program

Objective: to compare the early post-operative functional status and the efficacy of the cardiac rehabilitation program (CRP) after isolated left-sided valvular surgery or with concomitant tricuspid valve repair (TVR). Methods: we retrospectively enrolled patients admitted to the Cardiac Rehabilitation Unit of our institution from January 2014 to January 2019, following mitral or aortic valve surgery. In agreement with current guidelines, concomitant tricuspid annuloplasty was added to patients with severe functional tricuspid regurgitation (TR) and in those with mild to moderate TR when annulus dilatation was present. A 6-minute walk test (6mWT) was performed within the second day of admission and repeated predischarge. The distances walked on the 6mWT were reported as absolute value and as a percentage of the predicted value, taking into account anthropometric variables. Changes in the 6mWT performance and Barthel index (BI) were assessed to evaluate the impact of CRP on exercise tolerance and functional independence, respectively. Results: of 117 patients, 62 (53%) had isolated left-sided valvular surgery and 55 (47%) had concomitant TVR. There were no significant differences between the two groups in the baseline 6mWT performance and its improvement at the end of CRP. TVR was associated with a worse BI on admission, but with a greater improvement after the CRP and a pre-discharge BI comparable to isolated left-sided surgery. Upon linear regression analysis, diabetes and chronic renal disease were predictors of the baseline 6mWT performance. Conclusion: TVR does not affect the early post-operative functional status and the efficacy of the CRP after valvular surgery

Inhibition of de novo ceramide biosynthesis affects aging phenotype in an in vitro model of neuronal senescence.

Although aging is considered to be an unavoidable event, recent experimental evidence suggests that the process can be counteracted. Intracellular calcium (Ca2+i) dyshomeostasis, mitochondrial dysfunction, oxidative stress, and lipid dysregulation are critical factors that contribute to senescence-related processes. Ceramides, a pleiotropic class of sphingolipids, are important mediators of cellular senescence, but their role in neuronal aging is still largely unexplored. In this study, we investigated the effects of L-cycloserine (L-CS), an inhibitor of thede novoceramide biosynthesis, on the aging phenotype of cortical neurons cultured for 22 days, a setting employed as anin vitromodel of senescence. Our findings indicate that, compared to control cultures, 'aged' neurons display dysregulation of [Ca2+]ilevels, mitochondrial dysfunction, increased generation of reactive oxygen species (ROS), altered synaptic activity as well as the activation of neuronal death-related molecules. Treatment with L-CS positively affected the senescent phenotype, a result associated with recovery of neuronal [Ca2+]isignaling and reduction of mitochondrial dysfunction and ROS generation. The results suggest that thede novoceramide biosynthesis represents a critical intermediate in the molecular and functional cascade leading to neuronal senescence and identify ceramide biosynthesis inhibitors as promising pharmacological tools to decrease age-related neuronal dysfunctions