Cross-layer Perceptual ARQ for Video Communications over 802.11e Wireless Networks

This work presents an application-level perceptual ARQ algorithm for video streaming over 802.11e wireless networks. A simple and effective formula is proposed to combine the perceptual and temporal importance of each packet into a single priority value, which is then used to drive the packet-selection process at each retransmission opportunity. Compared to the standard 802.11 MAC-layer ARQ scheme, the proposed technique delivers higher perceptual quality because it can retransmit only the most perceptually important packets reducing retransmission bandwidth waste. Video streaming of H.264 test sequences has been simulated with ns in a realistic 802.11e home scenario, in which the various kinds of traffic flows have been assigned to different 802.11e access categories according to the Wi-Fi alliance WMM specification. Extensive simulations show that the proposed method consistently outperforms the standard link-layer 802.11 retransmission scheme, delivering PSNR gains up to 12 dB while achieving low transmission delay and limited impact on concurrent traffic. Moreover, comparisons with a MAC-level ARQ scheme which adapts the retry limit to the type of frame contained in packets and with an application-level deadline-based priority retransmission scheme show that the PSNR gain offered by the proposed algorithm is significant, up to 5 dB. Additional results obtained in a scenario in which the transmission relies on an intermediate node (i.e., the access point) further confirms the consistency of the perceptual ARQ performance. Finally, results obtained by varying network conditions such as congestion and channel noise levels show the consistency of the improvements achieved by the proposed algorithm

Qualitative smell/taste disorders as sequelae of acute COVID-19

Background Qualitative smell/taste disorders (such as phantosmia, parosmia, phantogeusia, and parageusia) have not yet been fully characterized in patients who had COVID-19, whereas quantitative disturbances (i.e., reduction/loss of smell/taste) have been widely investigated. Objective To simultaneously assess the presence of both quantitative and qualitative smell/taste dysfunctions in patients who suffered from COVID-19. Methods We enrolled 17 consecutive patients who suffered from COVID-19 over the last 6 months and 21 healthy controls, matched for sex and age. After a negative nasopharyngeal swab, the Sniffin’ Sticks Test and the Taste Strips were used to assess olfactory and taste function, respectively. At the same time, the presence of phantosmia, parosmia, phantogeusia, and parageusia was investigated with a standardized questionnaire. Results Qualitative disturbances of smell and/or taste were found in 6/17 (35.3%) patients. Phantosmia was reported in 2/17 (11.8%) patients and parosmia in 4/17 (23.5%). There were no significant differences in smell test scores between patients who reported phantosmia and/or parosmia and patients who did not. Phantogeusia was described in 3/17 (17.6%) patients, and parageusia was identified in 4/17 (23.5%) patients. All tested patients were normogeusic. Conclusion Around one-third of patients who recover from COVID-19 may have persistent qualitative dysfunction in smell/taste domains. Detection of phantogeusia in long-term COVID-19 patients represents a further novel finding. Further investigation is needed to better characterize the pathophysiology of phantosmia, parosmia, phantogeusia, and parageusia in patients who had COVID-19

EAG responses to pheromone as a tool in the control of population dynamics of the gypsy moth <i>Lymantria dispar</i>

The reproductive programme of the gypsy moth Lymantria dispar L. (Lepidoptera: Lymantriidae), the most important defoliator of Sardinian Quercus suber L. forests, is based on production and release of its sex pheromone (+)disparlure by calling female moths and its perception by conspecific males. The acquisition of information about any factors influencing male sensitivity to this sex attractant may help improve field techniques against this defoliator or possibly provide a basis for predicting where favourable conditions for control of population dynamics will occur. In this respect, the pheromone might be used as a specific tool for olfaction research and to monitor changes in male sensitivity, thus leading to a better control of population

Frequency and Determinants of Olfactory Hallucinations in Parkinson’s Disease Patients

Background: Olfactory dysfunctions and hallucinations are considered common nonmotor symptoms in Parkinson’s disease (PD). Visual and auditory hallucinations are well-known; however, olfactory hallucinations (OHs) are not fully investigated. The aim of this study was to evaluate OHs in PD patients, and their correlation to motor impairment, cognitive abilities, visual and auditory hallucinations, and olfactory and gustatory function. Methods: A sample of 273 patients was enrolled: 141 PD patients (mean age SD: 70.1 9.5 years) and 132 healthy controls (mean age SD: 69.4 9.6 years). In all patients, the following parameters were evaluated: motor symptoms (UPDRSIII), olfactory function, cognitive abilities, and occurrence of OH, gustatory hallucinations (GHs), and visual/auditory hallucinations. Results: OHs were found only in PD patients with a percentage of 11.3%. Among PD patients with OHs, 2.8% also presented GHs. High significant frequencies of females, the presence of visual/auditory hallucinations, and a high mean UPDRS-III score were found in patients with OHs related to patients without them. Binary logistic regression evidenced the presence of visual/auditory hallucinations and sex as main variables predicting the presence of OHs. Conclusions: Our data indicated that OHs occur frequently in PD patients, especially in women, and often concomitant with visual and auditory hallucinations, without any association with olfactory impairment

taly physical activity country profile: results from the first set of country cards of the Global Observatory for Physical Activity-GoPA!

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Improved results of the vacuum assisted closure and Nitinol clips sternal closure after postoperative deep sternal wound infection

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Contribution of MUTYH variants to male breast cancer risk: results from a multicenter study in Italy

Inherited mutations in BRCA1, and, mainly, BRCA2 genes are associated with increased risk of male breast cancer (MBC). Mutations in PALB2 and CHEK2 genes may also increase MBC risk. Overall, these genes are functionally linked to DNA repair pathways, highlighting the central role of genome maintenance in MBC genetic predisposition. MUTYH is a DNA repair gene whose biallelic germline variants cause MUTYH-associated polyposis (MAP) syndrome. Monoallelic MUTYH variants have been reported in families with both colorectal and breast cancer and there is some evidence on increased breast cancer risk in women with monoallelic variants. In this study, we aimed to investigate whether MUTYH germline variants may contribute to MBC susceptibility. To this aim, we screened the entire coding region of MUTYH in 503 BRCA1/2 mutation negative MBC cases by multigene panel analysis. Moreover, we genotyped selected variants, including p.Tyr179Cys, p.Gly396Asp, p.Arg245His, p.Gly264Trpfs*7, and p.Gln338His, in a total of 560 MBC cases and 1,540 male controls. Biallelic MUTYH pathogenic variants (p.Tyr179Cys/p.Arg241Trp) were identified in one MBC patient with phenotypic manifestation of adenomatous polyposis. Monoallelic pathogenic variants were identified in 14 (2.5%) MBC patients, in particular, p.Tyr179Cys was detected in seven cases, p.Gly396Asp in five cases, p.Arg245His and p.Gly264Trpfs*7 in one case each. The majority of MBC cases with MUTYH pathogenic variants had family history of cancer including breast, colorectal, and gastric cancers. In the case-control study, an association between the variant p.Tyr179Cys and increased MBC risk emerged by multivariate analysis [odds ratio (OR) = 4.54; 95% confidence interval (CI): 1.17-17.58; p = 0.028]. Overall, our study suggests that MUTYH pathogenic variants may have a role in MBC and, in particular, the p.Tyr179Cys variant may be a low/moderate penetrance risk allele for MBC. Moreover, our results suggest that MBC may be part of the tumor spectrum associated with MAP syndrome, with implication in the clinical management of patients and their relatives. Large-scale collaborative studies are needed to validate these findings