Constructing the ‘citizen’ in citizenship education

In the field of education, the discourses of ‘citizenship education’ aremore than at any other period of Canadian historycentre stage. As public schooling strives to offer citizenship education amenable to the needs of varied identities, the ideological premises, concepts, and goals of citizenship education must be interrogated. Critically synthesizing the developments of citizenship education since the Multiculturalism Policy of 1971, the gaps in citizenship education will be explored by discussing policy and pedagogical approaches. This article will conclude by offering pedagogical and conceptual alternatives to citizenship education, which can serve to address the outlined gaps in learning for citizenship for diverse learners

The Role and Position of Veil (Cover) in Promoting Family and Woman’s Spiritual Health

Veil (hijab) is one of the most important elements in the spiritual health of women. This study aimed to investigate the relationship between the veil and spiritual health in women and its impact on the spiritual health of the family, and to explain this issue in the dimension of the health of women and family as well as community by referring to some psychological effects of the veil (hijab). The veil enhances the value of women and above all provides their mental security with protection of human emotions and adherence to moral principles. Veil is responsible for strengthening the family foundation, and guarantees its spiritual health and is as a phenomenon effective in providing family health, which appears as a dynamic and pioneer attribute and saves the family from disintegration. This paper deals with components that consider the veil as a prominent factor in the health of woman and family. The research method used in this study was library method through content analysis

The most effective sexual function and dysfunction interventions in individuals with multiple sclerosis: A systematic review and meta-analysis

Background: Sexual dysfunction has many factors in multiple sclerosis, but there is no reliable treatment for this challenge. Objective: Determining effective sexual function or dysfunction interventions in individuals with multiple sclerosis. Materials and Methods: To find the relevant published interventional studies that at least had an English abstract or in Persian, we searched International Statistical Institute, PubMed, Scopus, Cochrane, Medline, PsycINFO, EMBASE, CINAHL, and Google Scholar from January 1990 to June 2021. The results were analyzed using RevMan 5.3 software. The p < 0.05 was considered significant. Results: Out of 568 articles, 41 were included after deleting the duplicate and irrelevant articles. Studies were divided into 2 groups of sexual function (n = 27) and dysfunction (n = 14). Interventions in each category have 4 subgroups: psychoeducational, exercise and rehabilitation, and medical and multi-type interventions. For improving sexual function, more than half of psychoeducational interventions showed a significant improvement after interventions (p = 0.0003). In sexual dysfunction studies, most of the interventions (n = 13/14) had improved at least one subscale of sexual dysfunction. Medical interventions were effective on men’s sexual dysfunction, and psychoeducational interventions had been more effective in women’s sexual dysfunction. Conclusion: Psychoeducational and medical interventions are the commonest effective interventions. The psychoeducational studies conducted specifically on women had a positive impact, and only 4 articles with medical interventions were specifically targeted at men, which had a positive effect. Key words: Clinical trial, Multiple sclerosis, Sexual dysfunction, Systematic review

"Through the kaleidoscope": Intersections between theoretical perspectives and classroom implications in Critical Global Citizenship Education

This paper presents a multi-voiced examination of educating for global citizenship from critical, interdisciplinary perspectives. The paper explores how insights from theoretical work on multiculturalism, race, religion, gender, language and literacy, and eco-justice can contribute to a critical global citizenship education practice. It reports the learning of a group of six Canadian PhD Candidates, who engaged in a year-long collaborative process to explore critical approaches to global citizenship education by focusing on key intersecting concerns, particularly critically understanding globalization. Drawing on theoretical considerations and discussions, the authors consider pedagogical implications for classroom teaching and learning.Cet article présente un examen multidirectionnel de l'éducation pour une citoyenneté mondiale au travers de perspectives critiques et interdisciplinaires. L'article explore comment un aperçu du travail théorique sur le multiculturalisme, la race, la religion, le sexe, la langue, la litératie, et l'éco-justice peuvent contribuer à une pratique critique de l'éducation sur la citoyenneté mondiale. Il rend compte de l'apprentissage d'un groupe de six canadiens, candidats au doctorat, qui se sont engagés dans un processus collaboratif d'une année, visant à explorer des approches critiques de l'éducation sur la citoyenneté mondiale en se concentrant sur les principales préoccupations entrecroisées, en particulier la compréhension critique de la mondialisation. S'appuyant sur des réflexions et des discussions théoriques, les auteurs considèrent les implications pédagogiques de l'enseignement et de l'apprentissage en classe

Pre- and post-treatment of α-Tocopherol on cognitive, synaptic plasticity, and mitochondrial disorders of the hippocampus in icv-streptozotocin-induced sporadic Alzheimer’s-like disease in male Wistar rat

ObjectiveMost dementia cases in the elderly are caused by Alzheimer’s disease (AD), a complex, progressive neurological disease. Intracerebroventricular (ICV) administration of streptozotocin (STZ) in rat’s results in aberrant brain insulin signaling, oxidative stress, and mitochondrial dysfunction that impair cognition change neural plasticity, and eventually lead to neuronal death. The current study aims to define the neuroprotective action of alpha-tocopherol in enhancing mitochondrial function and the function of synapses in memory-impaired rats brought on by icv-STZ.MethodsMale Wistar rats were pre-treated with (α-Tocopherol 150 mg/kg) orally once daily for 7 days before and 14 days after being bilaterally injected with icv-STZ (3 mg/kg), while sham group rats received the same volume of STZ solvent. After 2 weeks of icv-STZ infusion, rats were tested for cognitive performance using a behaviors test and then were prepared electrophysiology recordings or sacrificed for biochemical and histopathological assays.ResultsThe cognitive impairment was significantly minimized in the behavioral paradigms for those who had taken α-Tocopherol. In the hippocampus of icv-STZ rat brains, α-Tocopherol ocopherol effectively prevented the loss of glutathione levels and superoxide dismutase enzyme activity, lowered mitochondrial ROS and mitochondrial membrane potential, and also brought about a decrease in Aβ aggregation and neuronal death.ConclusionOur findings demonstrated that by lowering neurobehavioral impairments caused by icv-STZ, oxidative stress, and mitochondrial dysfunction, α-Tocopherol enhanced intracellular calcium homeostasis and corrected neurodegenerative defects in the brain. These findings examine the available approach for delaying AD connected to mitochondrial malfunction and plasticity issues

Investigation the Suitability of Patient Education Pamphlets and Patient Satisfaction among Teaching Hospitals in 2015

Background: To make the best use of written information in education pamphlets, suitability criteria developed for instructional materials. Moreover, client satisfaction with the quality of written materials provided in hospitals for patients needs to be taken into account. Aim: Therefore, the present study aimed to assess the suitability of patient education pamphlets and patient satisfaction among teaching hospitals in Mashhad, Iran. Method: A total number of 542 patient education pamphlets developed in 11 teaching hospitals in Mashhad was collected via a census method and their suitability was investigated using Suitability Assessment of Materials (SAM) instrument. Subsequently, satisfaction with education pamphlets among 2820 hospitalized patients was evaluated using a questionnaire designed based on SAM instrument. The association between the suitability of the given pamphlets and patient satisfaction was also determined. Descriptive statistics and the Chi-square test were used to analyze the findings. Results: The results revealed that 33.3% and 66.7% of the given pamphlets fell into the superior and adequate categories in terms of suitability, respectively. With regard to the satisfaction level, 0.7%, 26.4%, and 72.9 % of the patients were poorly, fairly, and completely satisfied with the pamphlets, respectively. Moreover, the pamphlets rated the higher suitability by patients obtained the higher satisfaction scores. Implications for Practice: The results of this study indicated a need for reconsiderations in some suitability factors for the pamphlets. In this respect, the factors of cultural appropriateness as well as layout and typography rated as acceptable

Severe Persistent Eczema in a Recipient of the Gam-COVID-Vac vaccine

Since the beginning of the COVID-19 pandemic, efforts have been made to design safe and effective vaccines against SARS-CoV-2.Numerous vaccines have been designed and tested in limited clinical trials in various countries. Among them, the Sputnik V vaccine has shown a relatively safe profile and, to our knowledge, has no associated major side effects. We describe the case of a 40-year-old female healthcare worker who developed severe persistent eczematous lesions on the second day after she received the first dose of the Sputnik vaccine. The eczematous lesions were refractory to an antihistamine and persisted at the 1 month follow-up. Severe persistent eczematous lesions should be viewed as a potential side effect of vaccination with the Sputnik V vaccine. Moreover, a severe allergic reaction to a COVID-2019 vaccine may indicate the vaccine is ineffective in the recipient

Methylmalonic aciduria as a biochemical marker for mitochondrial DNA depletion syndrome in patients with developmental delay and movement disorders: a case series

BackgroundMitochondrial DNA (mtDNA) depletion syndromes (MDDS) are genetically and clinically variable disorders resulting from a reduction in mtDNA content in the cells, tissues, and organ systems, leading to symptoms related to energy deficits. Deficiency of the mitochondrial succinyl-CoA ligase/synthetase enzyme secondary to pathogenic variations in the SUCLG1 and SUCLA2 genes is a subtype of MDDS that presents with neurological manifestations and a specific biochemical profile.MethodsThis cross-sectional series describes five patients with MDDS secondary to pathogenic variations in the SUCLG1 and SUCLA2 genes from two tertiary care centers in Canada and India. Clinical data concerning the course, investigations, and outcome were gathered through chart reviews.ResultsAll subjects presented in early infancy with neurological manifestations, including movement disorder, psychomotor regression, developmental delay, hearing loss, behavioral issues, or a combination thereof. Elevated methylmalonic acid metabolites, an abnormal acylcarnitine profile, and lactic acidemia were noted in the biochemical profile of each patient (n = 5/5, 100%). Molecular genetic testing disclosed the presence of pathogenic homozygous mutations in four subjects and compound heterozygosity in one subject.ConclusionMDDS associated with SUCLG1 and SUCLA2 genes can be detected biochemically by the presence of methylmalonic aciduria besides the elevation of lactate, C3, C4DC, and C5-OH acylcarnitine. Conducting metabolic workups including MMA and acylcarnitine profiles in patients with heterogeneity of clinical symptoms associated with the presence of this biochemical marker may potentially reduce the time to diagnosis and management

Diabetic Neuropathy and Axon Reflex-Mediated Neurogenic Vasodilatation in Type 1 Diabetes

Objective: Axon reflex-mediated neurogenic vasodilatation in response to cutaneous heating may reflect early, pre-clinical small fibre dysfunction. We aimed to evaluate the distribution of the vascular flare area measured by laser doppler imaging (‘‘LDI FLARE area’’) in type 1 diabetes and in healthy volunteers. Research and Methods: Concurrent with clinical and electrophysiological examination to classify diabetic sensorimotor polyneuropathy (DSP), LDIFLARE area (cm 2) was determined in 89 type 1 diabetes subjects matched to 64 healthy volunteers. We examined the association and diagnostic performance of LDI with clinical and subclinical measures of DSP and its severity. Results: Compared to the 64 healthy volunteers, the 56 diabetes controls without DSP had significantly lower LDIFLARE area (p = 0.006). The 33 diabetes cases with DSP had substantially lower LDIFLARE area as compared to controls without DSP (p = 0.002). There was considerable overlap in LDIFLARE area between all groups such that the ROC curve had an AUC of 0.72 and optimal sensitivity of 70 % for the detection of clinical DSP. Use of a subclinical definition for DSP, according to subclinical sural nerve impairment, was associated with improved AUC of 0.75 and sensitivity of 79%. In multivariate analysis higher HbA1c and body mass index had independent associations with smaller LDIFLARE area. Conclusions: Axon reflex-mediated neurogenic vasodilatation in response to cutaneous heating is a biomarker of earl