27 research outputs found
Current situation of specialist medical training in Spain
Producción CientÃficaLa formación de especialistas en ciencias de la salud se ha mantenido casi inalteradadurante varias décadas, pero a partir de la publicación del Real Decreto de Troncalidad, dereespecialización troncal y áreas de capacitación especÃfica, el clásico sistema MIR puede sufrirprofundos cambios. Repasamos en este artÃculo la evolución del mismo en nuestro paÃs.Specialist medical training through the Internal Medical Resident system has remai-ned almost unchanged for several decades, but now it is due to experience profound changessince the publication of the ‘‘Troncalidad’’ and specific training areas ordinance. In this article,we review its evolution in our country
Comparison study between colorimetric method and flame atomic absorption spectrophotometry in serum zinc status
Introduction: Zinc is an essential trace element for human
life and its deficiency affects human growth and development.
Serum zinc concentration (SZnC) provides useful information
in the clinical categorization of deficiency and
toxicity states.
Objectives: This paper presents a comparison study of
Flame Atomic Absorption Spectrometry (FASS) and the
Colorimetric method in the analysis of SZnC and hypozincemia.
Methods: The serum concentrations of zinc of 93 patients
(1 to 31 years old) with chronic diseases were used for analysis.
Statistical analytical: for SZnC, Pearson correlation coefficient,
simple linear regression analysis, Bland & Altman
method (B&A), and concordance correlation coefficient (CCC)
were valued; and for hypozincemia, the differences were
studied and Cohen’s Kappa index was used.
Results: The main results indicate the means of the SZnC
by both methods presented neither significant difference
(p=0.328) nor linear relation (R=0.18, p=0.077). Furthermore,
the percentage of cases of hypozincemia by the
Colorimetric method was almost double (13%) than by the
FASS (8%). There was only one coincident case in both methods
at <70 μg/dl.
Discussion: The Colorimetric method in hypozincemia
ranges predicted lower values with the FASS. This concordance
poor between both methods was corroborated with a
concordance correlation coefficient (CCC) lowly of 0.17.
Moreover, the Cohen’s Kappa index (-0.013) shown a concordance
poor between both methods, too. In other studies, the
variability of SZnC by Colorimetric method is more than FASS.
Conclusion: In summary, despite that, the mean of
serum concentrations of zinc by both methods is similar;
the diagnosis of cass with hypozincemia is not. The degree
of agreement between methods is poor, with a poor
strength of concordance to diagnosis hypozincemia.
Therefore, we recommended the use of FASS to evaluated
zinc status and diagnosis of hypozincemia, instead of the
Colorimetric method
Análisis nutricional y de la ingesta dietética en niños con enfermedad celÃaca y dieta exenta de gluten
Los autores de este artÃculo llevan a cabo una valoración del estado nutricional, del contenido en nutrientes de la alimentación y de sus hábitos dietéticos, en enfermos celÃacos con dieta exenta de gluten (DEG) y niños control
Análisis nutricional y de la ingesta dietética en niños con enfermedad celÃaca y dieta exenta de gluten
Los autores de este artÃculo llevan a cabo una valoración del estado nutricional, del contenido en nutrientes de la alimentación y de sus hábitos dietéticos, en enfermos celÃacos con dieta exenta de gluten (DEG) y niños control
Estado nutricional de zinc en una serie de pacientes con enfermedades crónicas
Dado que el zinc es un elemento esencial para todas las formas de vida, se realizó un estudio transversal con el objetivo de investigar el estado nutricional de zinc en una serie de pacientes infanto-juveniles con enfermedades crónica de diferente etiologÃa. Se evaluó el porcentaje de niños menores de cinco años con retraso de crecimiento (RC), la prevalencia de casos con hipozincemia y con deficiente ingesta de zinc. El 22% de niños menores de 5 años tuvo RC, el 62% deficiencia dietética de zinc y el 8% hipozincemia. Por lo tanto, el 65% de la serie presenta alto riesgo de deficiencia de zinc
Zinc nutritional status in a series of Children with chronic diseases: A cross-sectional study
Producción CientÃficaZinc is an essential trace element for the normal growth and development of human beings. The main objective was to evaluate the nutritional status of zinc and its association with nutritional indicators in a series of children with chronic diseases. Methods: The prevalence of patients with dietary zinc deficiency or deficit zinc intake (<80% DRI: dietary reference intake) was analyzed through prospective 72 h dietary surveys, and serum zinc deficiency or hypozincemia (≤70 µg/dL in children under 10 years of age in both sexes and in females older than 10 years and <74 µg/dL in males older than 10 years) was measured through atomic absorption spectrophotometry. The participants were classified according to their nutritional status by body mass index (BMI). Results: Mean serum zinc level in obese (87 µg/dL), undernourished (85 µg/dL), and eutrophic children (88 µg/dL) were normal, but in the undernutrition (60% DRI) and eutrophic (67% DRI) groups the mean dietary zinc intake was low compared to that in the obesity group (81% DRI). There were different associations between nutritional parameters, dietary zinc intake, and serum zinc. All patients with hypozincemia had dietary zinc deficiency. Conclusions: In the whole series, 69%of participants showed a zinc intake lower than recommended and might be at high risk of zinc deficiency
Increased resting energy expenditure by fat-free mass in children and teenagers with constitutional leanness
Producción CientÃficaTo compare the resting energy expenditure (REE) and the REE/Fat-free-mass (FFM) quotient in children with constitutional leanness (CL) and children with normal body weight, and to describe the within-family clustering of CL. SUBJECTS/
METHODS: We have studied 18 children and teenagers with CL, 10 girls and 8 boys, and 18 gender and age matched normal controls, with the same pubertal stage. All were recruited from the outpatient pediatric clinic nutrition unit. None of the children with CL showed symptoms of chronic illness, they had normal laboratory results, they had a normal caloric food intake, and they did not agree with the DSM-IV-TR criteria for anorexia nervosa. We describe the body mass index (BMI) of children and their parents. The children were classified according to Cole's recently published BMI cut-offs for thinness: under 18.5 points in CL group, stable at least in the last year, and between 18.5 and 25 cutt-offs in the control group. The body composition was calculated by anthropometric methods (skinfold thickness measurements). In addition REE was measured using fasting indirect calorimetry.
The CL group had a higher mean percentage of FFM, and a mean FM significantly less, relative to controls (p < 0.001). The average absolute REE was significantly lower in the CL group (1,106.55 ± 240.72 kcal) than the control group (1,353.33 ± 270.01 kcal/dia) (p < 0.01). However, the REE adjusted for FFM showed a mean significantly greater in the CL group (41.39 ± 2.26 kcal/kg FFM) (Mean confidence interval (CI) 95 %: 40.33-42.45) than the controls (37.37 ± 3.06 kcal/kg FFM) (Mean CI 95 %: 35.93-38.81) (p < 0.001). Finally, in the family study, the mean BMI of fathers of CL group was significantly lower (p < 0.01), but there were not any differences in the mean BMI of mothers. Among parents with BMI known, 8 of 35 parents of CL group had an BMI lower 18.5, and only 2 of 36 parents in the control group (p < 0.05).
This increased energy expenditure-to-FFM ratio differentiates between CL and controls. These metabolic differences are probably genetically determined
Copper and Copper/Zn Ratio in a Series of Children with Chronic Diseases: A Cross-Sectional Study
Copper is an essential micronutrient for humans. A cross-sectional and comparative study was done to assess serum Cu levels and serum copper/zinc (Cu/Zn) ratio and its association with nutritional indicators in a series of children and adolescents with chronic diseases. Anthropomet-ric, biochemical, dietary, body composition, and bone densitometry assessments were carried out. Serum Cu and Zn were measured by atomic absorption spectrophotometry. Seventy-eight patients (55% women) participated. The mean serum Cu in the entire series and by nutritional status through body mass index (BMI) was normal. Serum Cu decreased significantly with age and was meaning-fully higher in children than in adolescents. The risk of finding altered Cu levels in children and men was higher than in adolescents and women, respectively. Twenty-two per cent of patients had abnormal serum copper levels, 13 had hypercupremia, and four had hypocupremia. The Cu/Zn ratio was greater than 1.00 for 87% of the patients, which is an indicator of an inflammatory state. All patients with hypozincemia and hypocupremia had deficient Zn intake, but only 65% of the patients with hypercupremia had dietary Zn deficiency. Consequently, the Cu/Zn ratio could indicate an inflammatory state and a high risk of zinc deficiency in this specific child population
Natural history of irritable bowel syndrome
Producción CientÃficaIBS). The aim of this study was to investigate the presence of chronic functional digestive symptoms in childhood, interviewing adult patients diagnosed with IBS, in an attempt to establish a relationship between them.
METHODS:
By means of a questionnaire, the history of colic, chronic diarrhea, functional abdominal pain, constipation and migraine in childhood, was analyzed in patients diagnosed with IBS according to the current Rome III criteria, and in control patients without known chronic digestive disorders. Fisher's exact test was used for comparison of frequencies.
RESULTS:
The IBS study group was made up of 40 patients (24 women; average age, 33.03 years), and the control group by 40 adults (22 women; average age, 29.62 years). IBS-diagnosed adults spoke about a significantly higher prevalence of chronic diarrhea (32.5/7.5%; odds ratio [OR], 7.01; 95% confidence interval [CI]: 26.84-1.80), and FAP (37.5/15%; OR, 4.30; 95%CI: 12.67-1.43) in their childhood, than the control group. There were no differences in the presence of other childhood functional symptoms. Interestingly, the present patients, when asked about the onset of symptoms that led to the diagnosis of IBS, referred to them mostly beginning in adulthood, not linking their current diagnosis of IBS with their background in childhood.
In a proportion of adults with IBS the natural history of their symptoms probably began during their childhood.(IBS). The aim of this study was to investigate the presence of chronic functional digestive symptoms in childhood, interviewing adult patients diagnosed with IBS, in an attempt to establish a relationship between them.
By means of a questionnaire, the history of colic, chronic diarrhea, functional abdominal pain, constipation and migraine in childhood, was analyzed in patients diagnosed with IBS according to the current Rome III criteria, and in control patients without known chronic digestive disorders. Fisher's exact test was used for comparison of frequencies.
The IBS study group was made up of 40 patients (24 women; average age, 33.03 years), and the control group by 40 adults (22 women; average age, 29.62 years). IBS-diagnosed adults spoke about a significantly higher prevalence of chronic diarrhea (32.5/7.5%; odds ratio [OR], 7.01; 95% confidence interval [CI]: 26.84-1.80), and FAP (37.5/15%; OR, 4.30; 95%CI: 12.67-1.43) in their childhood, than the control group. There were no differences in the presence of other childhood functional symptoms. Interestingly, the present patients, when asked about the onset of symptoms that led to the diagnosis of IBS, referred to them mostly beginning in adulthood, not linking their current diagnosis of IBS with their background in childhood.
In a proportion of adults with IBS the natural history of their symptoms probably began during their childhood
Abordaje nutricional de pacientes ingresados con anorexia nerviosa
Producción CientÃficaAnorexia nervosa (AN) is the most prevalent of eating disorders in children and adolescents, and its treatment is long and complex, involving a
multidisciplinary team. Nutritional rehabilitation and restoration of a healthy body weight is one of the central goals in the initial stages of inpatient
treatment. However, current recommendations on initial energy requirements for these patients are inconsistent, with a clear lack of controlled
studies, available scientifi c evidence and global consensus on the most effective and safe refeeding practices in hospitalized adolescents with
anorexia nervosa (AN). Conservative refeeding recommendations have been classically established in order to prevent the refeeding syndrome.
Nevertheless, various works have recently appeared advocating a higher initial caloric intake, without observing more complications or refeeding
syndrome, and allowing a shorter average stay. We present our experience in the treatment of restricting AN with a conservative progressive
treatment. We have obtained good results with this approach, which was well tolerated by patients, with no observing complications. As a consequence,
the medical team could establish a pact about the therapeutic goals with the patients in an easier way.La anorexia nerviosa (AN) es el trastorno del comportamiento alimentario más prevalente en niños y adolescentes; su tratamiento es largo y
complejo, e involucra a múltiples profesionales. La rehabilitación nutricional y la recuperación de un peso corporal normal es uno de los objetivos
centrales en las fases iniciales del tratamiento del paciente ingresado. Sin embargo, las recomendaciones actuales sobre los requerimientos
energéticos iniciales para estos pacientes son inconsistentes, con una clara ausencia de estudios controlados, evidencia cientÃfi ca disponible y
consenso global sobre la forma de realimentación más efectiva y segura en adolescentes ingresados con anorexia nerviosa (AN). Clásicamente
se han recomendado una realimentación conservadora para prevenir el sÃndrome de realimentación. No obstante, han aparecido recientemente
varios trabajos recomendado una ingesta calórica inicial más elevada, sin observar más complicaciones ni sÃndrome de realimentación, y asociadas
a estancias medias más cortas. Presentamos aquà nuestra experiencia en el tratamiento de la AN restrictiva con un tratamiento progresivo
conservador. Hemos obtenido buenos resultados con este abordaje, bien tolerando por los pacientes, y sin observar complicaciones. Gracias a
él, el equipo médico pudo establecer más fácilmente un acuerdo sobre los objetivos terapéuticos con el paciente