Protocol for the IDEAL-2 longitudinal study: Following the experiences of people with dementia and their primary carers to understand what contributes to living well with dementia and enhances active life

Background There is a major need for longitudinal research examining the experiences of people with dementia and their primary carers, as relatively little is known about how the factors associated with capability to ‘live well’ vary over time. The main aim of the IDEAL-2 study is to investigate how and why, over time, people with dementia and their primary carers might vary in their capability to live well with dementia, whilst exploring both their use of health and care services and their unmet needs. Methods IDEAL-2 will build on the Improving the experience of Dementia and Enhancing Active Life (IDEAL) cohort of 1547 people (who, at recruitment between July 2014 and July 2016, had mild-to-moderate dementia), and their 1283 primary carers in Great Britain. The existing cohort will be enriched with additional participants with mild-to-moderate dementia (and their primary carers where available and willing) from the following groups: people with rarer forms of dementia, and/or those who are ≥90 years or < 65 years of age at time of recruitment. We will assess the primary outcome, capability to live well with dementia, and the factors influencing it using questionnaires at yearly intervals for 3 years. Additionally, we will seek to link the cohort data with administrative data to obtain information about health service use. Some participants will be invited for in-depth face-to-face interviews. The cohort study will be supplemented by linked research focusing on: the co-production of new measures of living well; including the perspectives of people with advanced dementia living in residential care settings; including people with dementia from black, Asian, and minority ethnic groups; and understanding the experience of people living with undiagnosed dementia. Discussion IDEAL-2 will provide evidence about the key indicators of, and factors associated with, living well over the course of dementia and how these differ for particular subgroups. It will tell us which combinations of services and support are most beneficial and cost-effective. Moreover, the IDEAL-2 study will gather evidence from under-researched groups of people with dementia, who are likely to have their own distinct perceptions of living well.Alzheimer’s Society & The University of Exete

Effect of the use of natural gas–diesel fuel mixture on performance, emissions, and combustion characteristics of a compression ignition engine

A compression ignition engine with a mechanical fuel system was converted into common rail fuel system by means of a self-developed electronic control unit. The engine was modified to be operated with mixtures of diesel and natural gas fuels in dual-fuel mode. Then, diesel fuel was injected into the cylinder while natural gas was injected into intake manifold with both injectors controlled with the electronic control unit. Energy content of the sprayed gas fuel was varied in the amounts of 0% (only diesel fuel), 15%, 40%, and 75% of total fuel’s energy content. All tests were carried out at constant engine speed of 1500 r/min at full load. In addition to the experiments, the engine was modeled with a one-dimensional commercial software. The experimental and numerical results were compared and found to be in reasonable agreement with each other. Both NO x and soot emissions were dropped with 15% and 40%, respectively, energy content rates in gas–fuel mixture compared to only diesel fuel. However, an increase was observed in carbon monoxide emissions with 15% natural gas fuel addition compared to only diesel fuel. Although smoke emission was reduced with natural gas fuel addition, there was a dramatic increase in NO x emissions with 75% natural gas fuel addition