15,449 research outputs found
Three body systems with strangeness and exotic systems
We report on four 's and three 's, in the 1500 - 1800 MeV
region, as two meson - one baryon S-wave resonances found by solving
the Faddeev equations in the coupled channel approach, which can be associated
to the existing = -1, low lying baryon resonances. On the
other hand we also report on a new, hidden strangeness state, mostly made
of , with mass around 1920 MeV, which we think could be
responsible for the peak seen in the around this
energy. Finally we address a very novel topic in which we show how few body
systems of several mesons can be produced, with their spins aligned up
to J=6, and how these states found theoretically can be associated to several
known mesons with spins J=2,3,4,5,6.Comment: Talk at the 21st European Conference on Few Body Problems in Physics,
Salamanca, Sep. 201
Radiative corrections to the three-body region of the Dalitz plot of baryon semileptonic decays with angular correlation between polarized emitted baryons and charged leptons: The initial-baryon rest frame case
We complement the results for the radiative corrections to the s2.l angular
correlation of baryon semileptonic decays of Ref. [1] with the final results in
the rest frame of the decaying baryon.Comment: 7 pages, Revtex4, no figure
VLT and GTC observations of SDSS J0123+00: a type 2 quasar triggered in a galaxy encounter?
We present long-slit spectroscopy, continuum and [OIII]5007 imaging data
obtained with the Very Large Telescope and the Gran Telescopio Canarias of the
type 2 quasar SDSS J0123+00 at z=0.399. The quasar lies in a complex, gas-rich
environment. It appears to be physically connected by a tidal bridge to another
galaxy at a projected distance of ~100 kpc, which suggests this is an
interacting system. Ionized gas is detected to a distance of at least ~133 kpc
from the nucleus. The nebula has a total extension of ~180 kpc. This is one of
the largest ionized nebulae ever detected associated with an active galaxy.
Based on the environmental properties, we propose that the origin of the nebula
is tidal debris from a galactic encounter, which could as well be the
triggering mechanism of the nuclear activity. SDSS J0123+00 demonstrates that
giant, luminous ionized nebulae can exist associated with type 2 quasars of low
radio luminosities, contrary to expectations based on type 1 quasar studies.Comment: 6 pages, 5 figures. Accepted for publication in MNRAS Letter
Sharp emergence of feature-selective sustained activity along the dorsal visual pathway.
Sustained activity encoding visual working memory representations has been observed in several cortical areas of primates. Where along the visual pathways this activity emerges remains unknown. Here we show in macaques that sustained spiking activity encoding memorized visual motion directions is absent in direction-selective neurons in early visual area middle temporal (MT). However, it is robustly present immediately downstream, in multimodal association area medial superior temporal (MST), as well as and in the lateral prefrontal cortex (LPFC). This sharp emergence of sustained activity along the dorsal visual pathway suggests a functional boundary between early visual areas, which encode sensory inputs, and downstream association areas, which additionally encode mnemonic representations. Moreover, local field potential oscillations in MT encoded the memorized directions and, in the low frequencies, were phase-coherent with LPFC spikes. This suggests that LPFC sustained activity modulates synaptic activity in MT, a putative top-down mechanism by which memory signals influence stimulus processing in early visual cortex
X, Y and Z States
Many new states in the charmonium mass region were recently discovered by
BaBar, Belle, CLEO-c, CDF, D0, BESIII, LHCb and CMS Collaborations. We use the
QCD Sum Rule approach to study the possible structure of some of these states.Comment: Contribution for the proceedings of the "XII Quark Confinement and
the Hadron Spectrum - CONF12" conferenc
Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis.
Palmitic acid (PA) induces hepatocyte apoptosis and fuels de novo ceramide synthesis in the endoplasmic reticulum (ER). Myristic acid (MA), a free fatty acid highly abundant in copra/palmist oils, is a predictor of nonalcoholic steatohepatitis (NASH) and stimulates ceramide synthesis. Here we investigated the synergism between MA and PA in ceramide synthesis, ER stress, lipotoxicity and NASH. Unlike PA, MA is not lipotoxic but potentiated PA-mediated lipoapoptosis, ER stress, caspase-3 activation and cytochrome c release in primary mouse hepatocytes (PMH). Moreover, MA kinetically sustained PA-induced total ceramide content by stimulating dehydroceramide desaturase and switched the ceramide profile from decreased to increased ceramide 14:0/ceramide16:0, without changing medium and long-chain ceramide species. PMH were more sensitive to equimolar ceramide14:0/ceramide16:0 exposure, which mimics the outcome of PA plus MA treatment on ceramide homeostasis, than to either ceramide alone. Treatment with myriocin to inhibit ceramide synthesis and tauroursodeoxycholic acid to prevent ER stress ameliorated PA plus MA induced apoptosis, similar to the protection afforded by the antioxidant BHA, the pan-caspase inhibitor z-VAD-Fmk and JNK inhibition. Moreover, ruthenium red protected PMH against PA and MA-induced cell death. Recapitulating in vitro findings, mice fed a diet enriched in PA plus MA exhibited lipodystrophy, hepatosplenomegaly, increased liver ceramide content and cholesterol levels, ER stress, liver damage, inflammation and fibrosis compared to mice fed diets enriched in PA or MA alone. The deleterious effects of PA plus MA-enriched diet were largely prevented by in vivo myriocin treatment. These findings indicate a causal link between ceramide synthesis and ER stress in lipotoxicity, and imply that the consumption of diets enriched in MA and PA can cause NASH associated with lipodystrophy
Passive microrheology of soft materials with atomic force microscopy: A wavelet-based spectral analysis
International audienceCompared to active microrheology where a known force or modulation is periodically imposed to a soft material, passive microrheology relies on the spectral analysis of the spontaneous motion of tracers inherent or external to the material. Passive microrheology studies of soft or living materials with atomic force microscopy (AFM) cantilever tips are rather rare because, in the spectral densities, the rheological response of the materials is hardly distinguishable from other sources of random or periodic perturbations. To circumvent this difficulty, we propose here a wavelet-based decomposition of AFM cantilever tip fluctuations and we show that when applying this multi-scale method to soft polymer layers and to living myoblasts, the structural damping exponents of these soft materials can be retrieved. Local stiffness and internal friction of soft materials (passive or active such as living cells) have lately been addressed at the nanoscale thanks to the development of pico-to nano-Newton force sensing systems and of nanome-ter resolution position detection devices. 1 Atomic force mi-croscopy (AFM) is one of these methods, where a sharply tipped flexible cantilever is indented inside a material to extract its local viscoelasticity from the shift and spreading of the cantilever spectral resonance modes. 2–4 However, these estimations are limited to rather narrow frequency bands surrounding the cantilever resonance modes or their higher harmonics. Spectral decomposition of cantilever fluctuations in contact with soft living tissues in the low frequency range has more rarely been explored. The few attempts which can be found in the literature were performed with small amplitude harmonic excitations (50 nm) of the sample position driven by a piezo-translator, in the 0.1 to 100 Hz frequency range, for a small and finite number of frequencies. 5,6 Whereas passive (driven by thermal fluctuations) microrheology has been performed for the past two decades by a variety of techniques capturing micro-probe spatial fluctuations , 7 it has not been applied yet to AFM cantilever fluctuations. The limitation of AFM-based passive rheology in the low frequency range comes from the mixing of the background vibrations of the liquid chamber with the cantilever fluctuations given by the rheological response of the material which are difficult to disentangle by standard FFT-based spectral averaging methods. In this work, we show that in quasi-stationary situations, these limitations can be circumvented using a wavelet-based spectral analysis of micro-cantilever fluctuations under passive excitation. Two experimental applications to passive polymer layers and living adherent myoblast cells are reported. Based on the generalized Stokes-Einstein relation (GSER) and associated generalizing assumptions, 8 passive microrheology of soft materials enables the extraction of the frequency-dependent complex modulus GðxÞ which is common to a large class of soft materials (foams, emulsions, slur-ries, and cells). 9–11 The observed scaling laws are explained by a characteristic structural disorder and the metastability of these materials which are embodied under the name of " soft glassy materials " or structural damping model. 12 Their complex shear modulus behaves a
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