14,185 research outputs found
Assessing Euro-Med Trade Preferences: The Case of Entry Price Reduction
The EU protects some of its fruits and vegetables through the entry price system. This system consists on a two-tiered tariff, with high-priced exports paying an ad valorem tariff, whereas low-priced exports pay also a supplementary specific tariff. The breaking point between high and low export prices is the entry price level decided by the EU, generally the same level for all third countries. In a few cases, some Southern Mediterranean partners of the EU have agreed a reduced entry price for their exports, together with the more common ad valorem tariff reduction. Among the indicators used for gauge the value of preferences, there is no one devoted to this case of reduced entry price, hence we develop a new indicator that allows to split which part of the preferential gains corresponds to the entry price reduction and which part corresponds to the "usual" ad valorem tariff reduction. We apply this methodology to Moroccan clementines trade flows, with two main findings: 1) The entry price reduction ranges up to 39% of the economic value of preferences in some months; 2) Morocco is not maximizing the gains due to this reduction, and could take some trade and policy lessons, mainly trying to better fit to the concession or, if impossible, use it as negotiating capital in future reviews of the agreement.International Relations/Trade,
Impacto de las etiquetas em La interpretación de La escala de Likert
En este trabajo se comparan las distribuciones de las respuestas dadas a un cuestionario formulado en dos versiones, una con etiquetas representando el grado de acuerdo, frente a otra con etiquetas expresando la frecuencia de realización de una acción. Se examina la relación entre la percepción de cada etiqueta lingüística y las etiquetas frecuentistas mediante números borrosos. Se analiza la equivalencia entre ambos métodos, estudiando en detalle la equidistancia en la percepción de las etiquetas extremas. Se evalúan además las diferencias en función de la importancia del tema sobre el que se interroga
Constraints on economical 331 models from mixing of K, Bd and Bs neutral mesons
We analyze the effect of flavor changing neutral currents within 331 models.
In particular, we concentrate in the so-called "economical" models, which have
a minimal scalar sector. Taking into account the experimental measurements of
observables related to neutral K and B meson mixing, we study the resulting
bounds for angles and phases in the mixing matrix for the down quark sector,
and the mass and mixing parameters related to the new Z' gauge boson.Comment: 11 pages, 3 figures. Eqs. (8) and (9) corrected, to be published in
Phys. Rev.
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Good Codons, Bad Transcript: Large Reductions in Gene Expression and Fitness Arising from Synonymous Mutations in a Key Enzyme
Biased codon usage in protein-coding genes is pervasive, whereby amino acids are largely encoded by a specific subset of possible codons. Within individual genes, codon bias is stronger at evolutionarily conserved residues, favoring codons recognized by abundant tRNAs. Although this observation suggests an overall pattern of selection for translation speed and/or accuracy, other work indicates that transcript structure or binding motifs drive codon usage. However, our understanding of codon bias evolution is constrained by limited experimental data on the fitness effects of altering codons in functional genes. To bridge this gap, we generated synonymous variants of a key enzyme-coding gene in Methylobacterium extorquens. We found that mutant gene expression, enzyme production, enzyme activity, and fitness were all significantly lower than wild-type. Surprisingly, encoding the gene using only rare codons decreased fitness by 40%, whereas an allele coded entirely by frequent codons decreased fitness by more than 90%. Increasing gene expression restored mutant fitness to varying degrees, demonstrating that the fitness disadvantage of synonymous mutants arose from a lack of beneficial protein rather than costs of protein production. Protein production was negatively correlated with the frequency of motifs with high affinity for the anti-Shine-Dalgarno sequence, suggesting ribosome pausing as the dominant cause of low mutant fitness. Together, our data support the idea that, although a particular set of codons are favored on average across a genome, in an individual gene selection can either act for or against codons depending on their local context.Organismic and Evolutionary Biolog
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Age-related differences in breast cancer mortality according to race/ethnicity, insurance, and socioeconomic status.
BackgroundWe assessed breast cancer mortality in older versus younger women according to race/ethnicity, neighborhood socioeconomic status (nSES), and health insurance status.MethodsThe study included female breast cancer cases 18 years of age and older, diagnosed between 2005 and 2015 in the California Cancer Registry. Multivariable Cox proportional hazards modeling was used to generate hazard ratios (HR) of breast cancer specific deaths and 95% confidence intervals (CI) for older (60+ years) versus younger (< 60 years) patients separately by race/ethnicity, nSES, and health insurance status.ResultsRisk of dying from breast cancer was higher in older than younger patients after multivariable adjustment, which varied in magnitude by race/ethnicity (P-interaction< 0.0001). Comparing older to younger patients, higher mortality differences were shown for non-Hispanic White (HR = 1.43; 95% CI, 1.36-1.51) and Hispanic women (HR = 1.37; 95% CI, 1.26-1.50) and lower differences for non-Hispanic Blacks (HR = 1.17; 95% CI, 1.04-1.31) and Asians/Pacific Islanders (HR = 1.15; 95% CI, 1.02-1.31). HRs comparing older to younger patients varied by insurance status (P-interaction< 0.0001), with largest mortality differences observed for privately insured women (HR = 1.51; 95% CI, 1.43-1.59) and lowest in Medicaid/military/other public insurance (HR = 1.18; 95% CI, 1.10-1.26). No age differences were shown for uninsured women. HRs comparing older to younger patients were similar across nSES strata.ConclusionOur results provide evidence for the continued disparity in Black-White breast cancer mortality, which is magnified in younger women. Moreover, insurance status continues to play a role in breast cancer mortality, with uninsured women having the highest risk for breast cancer death, regardless of age
Proper motions of the HH1 jet
We describe a new method for determining proper motions of extended objects,
and a pipeline developed for the application of this method. We then apply this
method to an analysis of four epochs of [S~II] HST images of the HH~1 jet
(covering a period of ~yr).
We determine the proper motions of the knots along the jet, and make a
reconstruction of the past ejection velocity time-variability (assuming
ballistic knot motions). This reconstruction shows an "acceleration" of the
ejection velocities of the jet knots, with higher velocities at more recent
times. This acceleration will result in an eventual merging of the knots in
~yr and at a distance of from the outflow source, close to
the present-day position of HH~1.Comment: 12 pages, 8 figure
Lower Cretaceous (Hauterivian-Albian) ammonite biostratigraphy in the Maestrat Basin (E Spain)
Peer reviewedPublisher PD
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