4 research outputs found
Newborn interneurons in the accessory olfactory bulb promote mate recognition in female mice
<p>In the olfactory bulb of adult rodents, local interneurons are constantly replaced by immature precursors derived from the subventricular zone. Whether any olfactory sensory process specifically relies on this cell renewal remains largely unclear. By using the well known model of mating-induced imprinting to avoid pregnancy block, which requires accessory olfactory bulb (AOB) function, we demonstrate that this olfactory memory formation critically depends on the presence of newborn granule neurons in this brain region. We show that, in adult female mice, exposure to the male urine compounds involved in mate recognition increases the number of new granule cells surviving in the AOB. This process is modulated by male signals sensed through the vomeronasal organ and, in turn, changes the activity of the downstream amygdaloid and hypothalamic nuclei involved in the pregnancy block response. Chemical depletion of newly generated bulbar interneurons causes strong impairment in mate recognition, thus resulting in a high pregnancy failure rate to familiar mating male odors. Taken together, our results indicate that adult neurogenesis is essential for specific brain functions such as persistent odor learning and mate recognition.</p
Maisons-musées. La patrimonialisation des demeures des illustres
Ă€ partir du constat d’un engouement rĂ©cent pour les maisons-musĂ©es de femmes et d’hommes illustres, ce numĂ©ro aborde la très grande variĂ©tĂ© des lieux qui sont regroupĂ©s sous cette appellation, et prĂ©sente une analyse critique de leur difficile catĂ©gorisation. Sans s’attarder sur la nouveautĂ© prĂ©sumĂ©e de ce phĂ©nomène, il met au contraire en Ă©vidence, par une perspective historique, la genèse en fait fort ancienne de ces lieux, construits par des pratiques sociales tout autant que par leurs habitants ou les pouvoirs publics. Cette genèse est le fruit de processus lents, graduels, dilatĂ©s sur les temps longs du « devenir-patrimoine » et du « devenir-musĂ©e », dont tĂ©moignent les recherches publiĂ©es dans ce volume. L’approche internationale proposĂ©e permet une large perspective sur les traits communs et spĂ©cifiques de la musĂ©alisation de ces demeures, complĂ©tĂ©e par une grande diversitĂ© d’approches mĂ©thodologiques et d’objets de recherche. Acknowledging the recent enthusiasm for house museums, homes to illustrious men and women, this issue discusses the wide variety of spaces understood as such and the difficulty to categorize them, through a critical analysis. Far from dwelling on the supposed novelty of this phenomenon, the issue rather adopts a historical perspective and underlines the long-distant origin of this type of museum, made up of social practices of local inhabitants as much as the institutions. This is the result of slow, gradual processes of “becoming heritage” and “becoming a museum”, as show the papers in this issue. The issue’s international perspective allows a wide perspective capturing both to the commonalities and specificities of the muzealisation process for these homes, as well as a wide variety of methodological approaches and research themes. A partir de la observaciĂłn de un interĂ©s reciente por las casas-museos de mujeres y hombres ilustres, este nĂşmero analiza la gran variedad de lugares que responden a este nombre, y presenta un análisis crĂtico de su difĂcil categorizaciĂłn. Sin insistir en la presunta novedad de este fenĂłmeno, resalta, por el contrario, a travĂ©s de una perspectiva histĂłrica, la muy antigua gĂ©nesis de estos lugares, construidos tanto por las prácticas sociales como por sus habitantes o por las autoridades pĂşblicas. Esta gĂ©nesis es el resultado de procesos lentos, graduales y dilatados del «devenir patrimonio» y «devenir museo», como lo demuestran las investigaciones publicadas en este volumen. El enfoque internacional propuesto, ofrece una perspectiva amplia sobre las caracterĂsticas comunes y especĂficas de la musealizaciĂłn de estas residencias, complementada por una gran variedad de enfoques metodolĂłgicos y objetos de investigaciĂłn