3,793 research outputs found
Population structure, phenotypic information and association studies in long-generation crops
Poster presented at Generation Challenge Program Annual Research Meeting. Sao Paulo (Brazil), 12-16 Sep. 200
Obstruction theory on 8-manifolds
This note gives a uniform, self-contained, and fairly direct approach to a
variety of obstruction-theoretic problems on 8-manifolds. We give necessary and
sufficient cohomological critera for the existence of almost complex and almost
quaternionic structures on the tangent bundle and for the reduction of the
structure group to U(3) by the homomorphism U(3) --> O(8) given by the Lie
algebra representation of PU(3).Comment: 19 page
Rules of Engagement: design attributes for social interactions
We present a taxonomy for the design of workplace âbreakâ spaces. The taxonomy can be used to identify aspects of current spaces that are either successful or problematic. From this analysis, we demonstrate how the taxonomy can be used to identify opportunities for computer mediated augmentation of spaces, and how such designs can be validated against this taxonomy
Probing Intermediate Mass Higgs Interactions at the CERN Large Hadron Collider
We analyze the potentiality of the CERN Large Hadron Collider to probe the
Higgs boson couplings to the electroweak gauge bosons. We parametrize the
possible deviations of these couplings due to new physics in a model
independent way, using the most general dimension--six effective lagrangian
where the SU(2)_L x U(1)_Y is realized linearly. For intermediate Higgs masses,
the decay channel into two photons is the most important one for Higgs searches
at the LHC. We study the effects of these new interactions on the Higgs
production mechanism and its subsequent decay into two photons. We show that
the LHC will be sensitive to new physics scales beyond the present limits
extracted from the LEP and Tevatron physics.Comment: 13 pages, 1 figure included using epsfig, RevTe
The Identification of Effective Welfare Indicators for Laboratory-Housed Macaques using a Delphi Consultation Process
Pairwise Force SPH Model for Real-Time Multi-Interaction Applications
In this paper, we present a novel pairwise-force smoothed particle hydrodynamics (PF-SPH) model to allow modeling of various interactions at interfaces in real time. Realistic capture of interactions at interfaces is a challenging problem for SPH-based simulations, especially for scenarios involving multiple interactions at different interfaces. Our PF-SPH model can readily handle multiple kinds of interactions simultaneously in a single simulation; its basis is to use a larger support radius than that used in standard SPH. We adopt a novel anisotropic filtering term to further improve the performance of interaction forces. The proposed model is stable; furthermore, it avoids the particle clustering problem which commonly occurs at the free surface. We show how our model can be used to capture various interactions. We also consider the close connection between droplets and bubbles, and show how to animate bubbles rising in liquid as well as bubbles in air. Our method is versatile, physically plausible and easy-to-implement. Examples are provided to demonstrate the capabilities and effectiveness of our approach
Perkutane transluminale Angioplastie (PTA) von iliakalen und femoropoplitealen GefĂ€Ăobstruktionen:FrĂŒh- und Langzeitergebnisse bei Patienten eines interdisziplinĂ€ren GefĂ€Ăzentrums
In der vorgelegten Dissertation werden die Ergebnisse von 1582 perkutanen transluminalen Angioplastien von iliakalen, femoropoplitealen und kruralen GefĂ€Ăokklusionen im Beobachtungszeitraum 1994 bis 2001 evaluiert. Die Kontrolluntersuchungen auf etwaige Reokklusionen wurden in Form einer digitalen Subtraktionsangiographie post interventionem und mittels Bestimmung der Dopplerindices durchgefĂŒhrt. So wurden Daten von 7106 dopplersonographischen Nachuntersuchungen aufgelistet und statistisch hinsichtlich einer eventuellen VerĂ€nderung des Interventionsergebnisses analysiert. Der durchschnittliche Ankle-Brachial-Pressure-Index (ABPI) stieg im gesamten Studienzeitraum um 0,13 (20,6%) von 0,63 +-0,24 prĂ€interventionell auf 0,76 +-0,27 postinterventionell. Direkt nach PTA betrug der ABPI durchschnittlich 0,84 +-0,18. Die Offenheitsraten nach 7 Jahren betragen 71,4%, die Komplikationsrate liegt bei 6,7%, im Vergleich mit der aktuellen Studienlage sind dies sehr gute Ergebnisse
UVA irradiation of human skin vasodilates arterial vasculature and lowers blood pressure independently of nitric oxide synthase
The incidence of hypertension and cardiovascular disease correlates with latitude and rises in winter. The molecular basis for this remains obscure. As nitric oxide (NO) metabolites are abundant in human skin we hypothesised that exposure to UVA may mobilise NO bioactivity into the circulation to exert beneficial cardiovascular effects independently of vitamin D. In 24 healthy volunteers irradiation of the skin with 2 Standard Erythemal Doses of UVA lowered BP, with concomitant decreases in circulating nitrate and rises in nitrite concentrations. Unexpectedly, acute dietary intervention aimed at modulating systemic nitrate availability had no effect on UV-induced hemodynamic changes, indicating that cardiovascular effects were not mediated via direct utilization of circulating nitrate. UVA irradiation of the forearm caused increased blood flow independently of NO-synthase activity, suggesting involvement of pre-formed cutaneous NO stores. Confocal fluorescence microscopy studies of human skin pre-labelled with the NO-imaging probe DAF2-DA revealed that UVA-induced NO release occurs in a NOS-independent, dose-dependent fashion, with the majority of the light-sensitive NO pool in the upper epidermis. Collectively, our data provide mechanistic insights into an important function of the skin in modulating systemic NO bioavailability which may account for the latitudinal and seasonal variations of BP and cardiovascular disease.Journal of Investigative Dermatology accepted article preview online, 20 January 2014
Atmospheric lepton fluxes at ultrahigh energies
In order to estimate the possibility to observe exotic physics in a neutrino
telescope, it is essential to first understand the flux of atmospheric
neutrinos, muons and dimuons. We study the production of these leptons by
high-energy cosmic rays. We identify three main sources of muons of energy E >
10^6 GeV: the weak decay of charm and bottom mesons and the electromagnetic
decay of unflavored mesons. Contrary to the standard assumption, we find that
eta mesons, not the prompt decay of charm hadrons, are the dominant source of
atmospheric muons at these energies. We show that, as a consequence, the ratio
between the neutrino and muon fluxes is significantly reduced. For dimuons,
which may be a background for long-lived staus produced near a neutrino
telescope, we find that pairs of E ~ 10^7 GeV forming an angle above 10^-6 rad
are produced through D (80%) or B (10%) meson decay and through Drell-Yan
proceses (10%). The frequency of all these processes has been evaluated using
the jet code PYTHIA.Comment: 10 pages, 4 figures; published versio
Allopurinol and oxypurinol are hydroxyl radical scavengers
AbstractAllopurinol is a scavenger of the highly reactive hydroxyl radical (k2 approx. 109 Mâ1sâ1). One product of attack of hydroxyl radical upon allopurinol is oxypurinol, which is a major metabolite of allopurinol. Oxypurinol is a better hydroxyl radical scavenger than is allopurinol (k2 approx. 4 Ă 109 Mâ1sâ1) and it also reacts with the myeloperoxidase-derived oxidant hypochlorous acid. Hence the protective actions of allopurinol against reperfusion damage after hypoxia need not be entirely due to xanthine oxidase inhibition
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