The transverse-momentum spectrum of Higgs bosons near threshold at NNLO

We give next-to-next-to-leading order (NNLO) predictions for the Higgs production cross section at large transverse momentum in the threshold limit. Near the partonic threshold, all radiation is either soft or collinear to the final state jet which recoils against the Higgs boson. We find that the real emission corrections are of moderate size, but that the virtual corrections are large. We discuss the origin of these corrections and give numerical predictions for the transverse-momentum spectrum. The threshold result is matched to the known NLO result and implemented in the public code PeTeR.Comment: 17 pages, 9 Figures; v2: journal version, correction in the qg channe

Transverse-momentum spectra of electroweak bosons near threshold at NNLO

We obtain the next-to-next-to-leading order corrections to transverse-momentum spectra of W, Z and Higgs bosons near the partonic threshold. In the threshold limit, the electroweak boson recoils against a low-mass jet and all radiation is either soft, or collinear to the jet or the beam directions. We extract the virtual corrections from known results for the relevant two-loop four-point amplitudes and combine them with the soft and collinear two-loop functions as defined in Soft-Collinear Effective Theory. We have implemented these results in a public code PeTeR and present numerical results for the threshold resummed cross section of W and Z bosons at next-to-next-to-next-to-leading logarithmic accuracy, matched to next-to-leading fixed-order perturbation theory. The two-loop corrections lead to a moderate increase in the cross section and reduce the scale uncertainty by about a factor of two. The corrections are significantly larger for Higgs production.Comment: 33 pages, 3 figures; v2: journal version, correction in (73); v3: corrected qg-channel in (73

Translesion DNA synthesis in the context of cancer research

During cell division, replication of the genomic DNA is performed by high-fidelity DNA polymerases but these error-free enzymes can not synthesize across damaged DNA. Specialized DNA polymerases, so called DNA translesion synthesis polymerases (TLS polymerases), can replicate damaged DNA thereby avoiding replication fork breakdown and subsequent chromosomal instability

Ten Years After Arterial Bypass Surgery for Claudication: Venous Bypass is the Primary Procedure for TASC C and D Lesions

Background: The appropriate role for surgery and endovascular therapy for severe intermittent claudication (IC) remains controversial. We present our results after infrainguinal autogenous bypass for severe IC more than 10years ago giving a reasoned argument to perform vein bypass as the primary procedure for severe IC. Methods: Our prospectively designed database includes more than 1,000 infrainguinal bypasses following an all-autogenous policy. For this review only patients operated on for severe IC at least 10years ago were included. The primary end points were survival and primary and assisted-primary patency rates. Results: From October 1988 until December 2000, 124 bypasses for IC were performed. Ninety-five patients were male and the mean age was 64.5±10.8years. Survival after 10years was 50.3% according to life table analysis. Forty bypasses were to the supragenicular artery, 62 to the infragenicular popliteal artery, and 22 to the tibial artery. Thirty-day mortality was 0.8% (1 patient). The primary patency rate after 10years was 63.5% and the assisted-primary patency rate 87.3%. Conclusion: Infrainguinal venous bypass for severe IC has excellent long-term results. Our results are strong arguments against the liberal use of stenting long lesions of the femoropopliteal artery. Venous bypass remains the primary procedure for TASC C and D lesions in claudicant

General-Relativistic MHD for the Numerical Construction of Dynamical Spacetimes

We assemble the equations of general relativistic magnetohydrodynamics (MHD) in 3+1 form. These consist of the complete coupled set of Maxwell equations for the electromagnetic field, Einstein's equations for the gravitational field, and the equations of relativistic MHD for a perfectly conducting ideal gas. The adopted form of the equations is suitable for evolving numerically a relativistic MHD fluid in a dynamical spacetime characterized by a strong gravitational field.Comment: 8 pages; scheduled for March 10 issue of Ap

Flood risk management based on 2D TELEMAC computations: an example with Swiss hazard map

A case study in Switzerland is considered, where hazard/flood maps are established as part of the planning of flood protection measures. Due to the commune’s location within a flat plain divided by a railway dike, it could be shown that the settlements an d infrastructures are much more endangered by floods than originally thought. Using the theme “land cover” of the digital cadastral survey , a digital terrain model (DTM) and bathymetry data, break lines were generated to build a triangular mesh . Culverts, tubes and bridges are a n important element of hazard mapping, as they can alter or create new flow paths not only as common bottlenecks in the channel ( overflow), but also outside in flooded settlement areas where pedestrian/road underpasses and tunnels a re present However, the modelling of culverts and tubes has revealed that they are no longer suitable from a certain size of the channel, as the flow passes by the point which define s the culvert. Thus, several workarounds were tested to improve the relia bility of the culverts/tubes Recorded floods have shown that buildings are not necessarily an impermeable obstacle for the flowing water. An approach was developed to consider buildings as floodable as well as impermeable, as it could be observed that lar ger building complexes may by traversed by floods and alter the flow paths in this way. If these aspects are taken into account, an informative hazard map may be established