2,675 research outputs found
The True Incidence of Magnetism among Field White Dwarfs
We study the incidence of magnetism in white dwarfs from three large and
well-observed samples of hot, cool, and nearby white dwarfs in order to test
whether the fraction of magnetic degenerates is biased, and whether it varies
with effective temperature, cooling age, or distance. The magnetic fraction is
considerably higher for the cool sample of Bergeron, Ruiz, and Leggett, and the
Holberg, Oswalt, and Sion sample of local white dwarfs that it is for the
generally-hotter white dwarfs of the Palomar Green Survey. We show that the
mean mass of magnetic white dwarfs in this survey is 0.93 solar masses or more,
so there may be a strong bias against their selection in the magnitude-limited
Palomar Green Survey. We argue that this bias is not as important in the
samples of cool and nearby white dwarfs. However, this bias may not account for
all of the difference in the magnetic fractions of these samples.
It is not clear that the magnetic white dwarfs in the cool and local samples
are drawn from the same population as the hotter PG stars. In particular, two
or threee of the cool sample are low-mass white dwarfs in unresolved binary
systems. Moreover, there is a suggestion from the local sample that the
fractional incidence may increase with decreasing temperature, luminosity,
and/or cooling age. Overall, the true incidence of magnetism at the level of 2
megagauss or greater is at least 10%, and could be higher. Limited studies
capable of detecting lower field strengths down to 10 kilogauss suggest by
implication that the total fraction may be substantially higher than 10%.Comment: 16 pages, 2 figures, Astronomical Journal in press -- Jan 2003 issu
Towards Better Integrators for Dissipative Particle Dynamics Simulations
Coarse-grained models that preserve hydrodynamics provide a natural approach
to study collective properties of soft-matter systems. Here, we demonstrate
that commonly used integration schemes in dissipative particle dynamics give
rise to pronounced artifacts in physical quantities such as the compressibility
and the diffusion coefficient. We assess the quality of these integration
schemes, including variants based on a recently suggested self-consistent
approach, and examine their relative performance. Implications of
integrator-induced effects are discussed.Comment: 4 pages, 3 figures, 2 tables, accepted for publication in Phys. Rev.
E (Rapid Communication), tentative publication issue: 01 Dec 200
Cognitive Sparing during the Administration of Whole Brain Radiotherapy and Prophylactic Cranial Irradiation: Current Concepts and Approaches
Whole brain radiotherapy (WBRT) for the palliation of metastases, or as prophylaxis to prevent intracranial metastases, can be associated with subacute and late decline in memory and other cognitive functions. Moreover, these changes are often increased in both frequency and severity when cranial irradiation is combined with the use of systemic or intrathecal chemotherapy. Approaches to preventing or reducing this toxicity include the use of stereotactic radiosurgery (SRS) instead of WBRT; dose reduction for PCI; exclusion of the limbic circuit, hippocampal formation, and/or neural stem cell regions of the brain during radiotherapy; avoidance of intrathecal and/or systemic chemotherapy during radiotherapy; the use of high-dose, systemic chemotherapy in lieu of WBRT. This review discusses these concepts in detail as well as providing both neuroanatomic and radiobiologic background relevant to these issues
The Formation Rate, Mass and Luminosity Functions of DA White Dwarfs from the Palomar Green Survey
Spectrophotometric observations at high signal-to-noise ratio were obtained
of a complete sample of 347 DA white dwarfs from the Palomar Green (PG) Survey.
Fits of observed Balmer lines to synthetic spectra calculated from
pure-hydrogen model atmospheres were used to obtain robust values of Teff, log
g, masses, radii, and cooling ages. The luminosity function of the sample,
weighted by 1/Vmax, was obtained and compared with other determinations. The
mass distribution of the white dwarfs is derived, after important corrections
for the radii of the white dwarfs in this magnitude-limited survey and for the
cooling time scales. The formation rate of DA white dwarfs from the PG is
estimated to be 0.6x10^(-12) pc^(-3) yr^(-1). Comparison with predictions from
a theoretical study of the white dwarf formation rate for single stars
indicates that >80% of the high mass component requires a different origin,
presumably mergers of lower mass double degenerate stars. In order to estimate
the recent formation rate of all white dwarfs in the local Galactic disk,
corrections for incompleteness of the PG, addition of the DB-DO white dwarfs,
and allowance for stars hidden by luminous binary companions had to be applied
to enhance the rate. An overall formation rate of white dwarfs recently in the
local Galactic disk of 1.15+/-0.25x10^(-12) pc^(-3) yr^(-1) is obtained. Two
recent studies of samples of nearby Galactic planetary nebulae lead to
estimates around twice as high. Difficulties in reconciling these
determinations are discussed.Comment: 73 pages, 18 figures, accepted for publication in the ApJ Supplemen
Defining childhood severe falciparum malaria for intervention studies.
Background Clinical trials of interventions designed to prevent severe falciparum malaria in children require a clear endpoint. The internationally accepted definition of severe malaria is sensitive, and appropriate for clinical purposes. However, this definition includes individuals with severe nonmalarial disease and coincident parasitaemia, so may lack specificity in vaccine trials. Although there is no “gold standard” individual test for severe malaria, malaria-attributable fractions (MAFs) can be estimated among groups of children using a logistic model, which we use to test the suitability of various case definitions as trial endpoints. Methods and Findings A total of 4,583 blood samples were taken from well children in cross-sectional surveys and from 1,361 children admitted to a Kenyan District hospital with severe disease. Among children under 2 y old with severe disease and over 2,500 parasites per microliter of blood, the MAFs were above 85% in moderate- and low-transmission areas, but only 61% in a high-transmission area. HIV and malnutrition were not associated with reduced MAFs, but gastroenteritis with severe dehydration (defined by reduced skin turgor), lower respiratory tract infection (clinician's final diagnosis), meningitis (on cerebrospinal fluid [CSF] examination), and bacteraemia were associated with reduced MAFs. The overall MAF was 85% (95% confidence interval [CI] 83.8%–86.1%) without excluding these conditions, 89% (95% CI 88.4%–90.2%) after exclusions, and 95% (95% CI 94.0%–95.5%) when a threshold of 2,500 parasites/μl was also applied. Applying a threshold and exclusion criteria reduced sensitivity to 80% (95% CI 77%–83%). Conclusions The specificity of a case definition for severe malaria is improved by applying a parasite density threshold and by excluding children with meningitis, lower respiratory tract infection (clinician's diagnosis), bacteraemia, and gastroenteritis with severe dehydration, but not by excluding children with HIV or malnutrition
Elaborating a coiledâ coilâ assembled octahedral protein cage with additional protein domains
De novo design of protein nanoâ cages has potential applications in medicine, synthetic biology, and materials science. We recently developed a modular, symmetryâ based strategy for protein assembly in which short, coiledâ coil sequences mediate the assembly of a protein building block into a cage. The geometry of the cage is specified by the combination of rotational symmetries associated with the coiledâ coil and protein building block. We have used this approach to design wellâ defined octahedral and tetrahedral cages. Here, we show that the cages can be further elaborated and functionalized by the addition of another protein domain to the free end of the coiledâ coil: in this case by fusing maltoseâ binding protein to an octahedral protein cage to produce a structure with a designed molecular weight of ~1.8 MDa. Importantly, the addition of the maltose binding protein domain dramatically improved the efficiency of assembly, resulting in ~ 60â fold greater yield of purified protein compared to the original cage design. This study shows the potential of using small, coiledâ coil motifs as offâ theâ shelf components to design MDaâ sized protein cages to which additional structural or functional elements can be added in a modular manner.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/146469/1/pro3497.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/146469/2/pro3497_am.pd
A Catalog of Spectroscopically Confirmed White Dwarfs from the Sloan Digital Sky Survey Data Release 4
We present a catalog of 9316 spectroscopically confirmed white dwarfs from
the Sloan Digital Sky Survey Data Release 4. We have selected the stars through
photometric cuts and spectroscopic modeling, backed up by a set of visual
inspections. Roughly 6000 of the stars are new discoveries, roughly doubling
the number of spectroscopically confirmed white dwarfs. We analyze the stars by
performing temperature and surface gravity fits to grids of pure hydrogen and
helium atmospheres. Among the rare outliers are a set of presumed helium-core
DA white dwarfs with estimated masses below 0.3 Msun, including two candidates
that may be the lowest masses yet found. We also present a list of 928 hot
subdwarfs.Comment: Accepted by the Astrophysical Journal Supplements, 25 pages, 24
figures, LaTeX. The electronic catalog, as well as diagnostic figures and
links to the spectra, is available at http://das.sdss.org/wdcat/dr4
On the angular momentum evolution of merged white dwarfs
We study the angular momentum evolution of binaries containing two white
dwarfs which merge and become cool helium-rich supergiants. Our object is to
compare predicted rotation velocities with observations of highly evolved stars
believed to have formed from such a merger, including RCrB and extreme helium
stars. The principal study involves a binary containing a 0.6 solar mass CO
white dwarf, and a 0.3 solar mass He white dwarf. The initial condition for the
angular momentum distribution is defined where the secondary fills its Roche
Lobe. We assume conservation of angular momentum to compute the angular
momentum distribution in a collisionless disk and subsequently in the giant
envelope. At the end of shell-helium burning, the giant contracts to form a
white dwarf. We derive the surface rotation velocity during this contraction.
The calculation is repeated for a range of initial mass ratios, and also for
the case of mergers between two helium white dwarfs; the latter will contract
to the helium main-sequence rather than the white dwarf sequence. Assuming
complete conservation of angular momentum, we predict acceptable angular
rotation rates for cool giants and during the initial subsequent contraction.
However such stars will only survive spin-up to reach the white dwarf sequence
(CO+He merger) if the initial mass ratio is close to unity. He+He merger
products must lose angular momentum in order to reach the helium main sequence.
Minimum observed rotation velocities in extreme helium stars are lower than our
predictions by at least one half, indicating that CO+He mergers must lose at
least one half of their angular momentum.Comment: 11 pages, 11 figures, MNRAS in pres
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