Arresting woodland bird decline in Australian agricultural landscapes: potential application of the European agri-environment model

This paper considered the applicability of the European model of land stewardship payments, in particular its support for biodiversity conservation in agricultural landscapes, to an Australian context. More broadly, the research approach described in the paper may also be applied to assessing the suitability of overseas stewardship schemes to the provision of any ecoservice in Australia, such as carbon sequestration and floodwater regulation

Clinical Utility of Cardiovascular Magnetic Resonance in Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is characterized by substantial genetic and phenotypic heterogeneity, leading to considerable diversity in clinical course including the most common cause of sudden death in young people and a determinant of heart failure symptoms in patients of any age. Traditionally, two-dimensional echocardiography has been the most reliable method for establishing a clinical diagnosis of HCM. However, cardiovascular magnetic resonance (CMR), with its high spatial resolution and tomographic imaging capability, has emerged as a technique particularly well suited to characterize the diverse phenotypic expression of this complex disease. For example, CMR is often superior to echocardiography for HCM diagnosis, by identifying areas of segmental hypertrophy (ie., anterolateral wall or apex) not reliably visualized by echocardiography (or underestimated in terms of extent). High-risk HCM patient subgroups identified with CMR include those with thin-walled scarred LV apical aneurysms (which prior to CMR imaging in HCM remained largely undetected), end-stage systolic dysfunction, and massive LV hypertrophy. CMR observations also suggest that the cardiomyopathic process in HCM is more diffuse than previously regarded, extending beyond the LV myocardium to include thickening of the right ventricular wall as well as substantial morphologic diversity with regard to papillary muscles and mitral valve. These findings have implications for management strategies in patients undergoing invasive septal reduction therapy. Among HCM family members, CMR has identified unique phenotypic markers of affected genetic status in the absence of LV hypertrophy including: myocardial crypts, elongated mitral valve leaflets and late gadolinium enhancement

Real Time Detection of Anomalous Satellite Behavior Has Ground Based Telescope Images

Air Force analysts are faced with the task of monitoring satellites with ground based telescopes. Images are collected and analyzed in a time consuming and subjective effort to detect any behavior that is anomalous. This research maximizes use of a priori information to create an automated, real time satellite behavior classification tool. Using modeling software and knowledge of a satellite\u27s orbit, reference imagery is created for each measured image in a satellite pass. Features are extracted from the measured and reference image pairs that provide good overall Gaussian classification accuracy (85%), reduce the dimensionality of the problem (from 32,768 down to 3), and are least dependent on data partitioning. The statistical image pair classifier is tested for robustness to atmospheric distortion, and training data requirements are explored. Satellite behavior is classified by counting the classification results for the image pairs in a satellite pass. A binomial analysis of the classification technique predicts virtually 100% classification accuracy of satellite behavior. This research demonstrates the validity of model based satellite behavior analysis

Cardiovascular Diseases That Have Emerged From the Darkness

It is important for both the patient and physician communities to have timely access to information recognizing rapid progress in the diagnosis and treatment of familiar but relatively uncommon cardiovascular diseases. Patients with 3 cardiovascular diseases (ie, hypertrophic cardiomyopathy, pulmonary arterial hypertension, and transthyretin (TTR) cardiac amyloidosis (ATTR)]), once considered rare without effective management options and associated with malignant prognosis, have now benefited substantially from the development of a variety of innovative therapeutic strategies. In addition, in each case, enhanced diagnostic testing has expanded the patient population and allowed for more widespread administration of contemporary treatments. In hypertrophic cardiomyopathy, introduction of implantable defibrillators to prevent sudden death as well as high-benefit:low-risk septal reduction therapies to reverse heart failure have substantially reduced morbidity and disease-related mortality (to 0.5% per year). For pulmonary arterial hypertension, a disease once characterized by a particularly grim prognosis, prospective randomized drug trials with aggressive single (or combined) pharmacotherapy have measurably improved survival and quality of life for many patients. In cardiac amyloidosis, development of disease-specific drugs can for the first time reduce morbidity and mortality, prominently with breakthrough ATTR-protein-stabilizing tafamidis. In conclusion, in less common and visible cardiovascular diseases, it is crucial to recognize substantial progress and achievement, given that penetration of such information into clinical practice and the patient community can be inconsistent. Diseases such as hypertrophic cardiomyopathy, pulmonary arterial hypertension, and ATTR cardiac amyloidosis, once linked to a uniformly adverse prognosis, are now associated with the opportunity for patients to experience satisfactory quality of life and extended longevity

Feline Hypertrophic Cardiomyopathy: A Spontaneous Large Animal Model of Human HCM.

Hypertrophic cardiomyopathy (HCM) is a common disease in pet cats, affecting 10-15% of the pet cat population. The similarity to human HCM, the rapid progression of disease, and the defined and readily determined endpoints of feline HCM make it an excellent natural model that is genotypically and phenotypically similar to human HCM. The Maine Coon and Ragdoll cats are particularly valuable models of HCM because of myosin binding protein-C mutations and even higher disease incidence compared to the overall feline population. The cat overcomes many of the limitations of rodent HCM models, and can provide enhanced translation of information from in vitro and induced small animal models to human clinical trials. Physicians and veterinarians working together in a collaborative and interdisciplinary approach can accelerate the discovery of more effective treatments for this and other cardiovascular diseases affecting human and veterinary patients

From Small-Scale Dynamo to Isotropic MHD Turbulence

We consider the problem of incompressible, forced, nonhelical, homogeneous, isotropic MHD turbulence with no mean magnetic field. This problem is essentially different from the case with externally imposed uniform mean field. There is no scale-by-scale equipartition between magnetic and kinetic energies as would be the case for the Alfven-wave turbulence. The isotropic MHD turbulence is the end state of the turbulent dynamo which generates folded fields with small-scale direction reversals. We propose that the statistics seen in numerical simulations of isotropic MHD turbulence could be explained as a superposition of these folded fields and Alfven-like waves that propagate along the folds.Comment: kluwer latex, 7 pages, 7 figures; Proceedings of the International Workshop "Magnetic Fields and Star Formation: Theory vs. Observations", Madrid, 21-25 April 2003 -- published version (but the e-print is free of numerous typos introduced by the publisher

Prevalence of suspected hypertrophic cardiomyopathy or left ventricular hypertrophy based on race and gender in teenagers using screening echocardiography

BACKGROUND:The goal of this study was to evaluate the prevalence of suspected hypertrophic cardiomyopathy (HCM) in a population of teenagers undergoing screening echocardiography for the detection of HCM.METHOD:The Anthony Bates Foundation performs screening echocardiography for the prevention of sudden death. A total of 2,066 students were studied between the ages of 13 to 19 years. Suspected HCM was defined as any wall thickness greater than or equal to] 15 mm. LVH was defined as wall thickness greater than or equal to] 13 mmRESULTS:Prevalence of suspected HCM was 0.7% (14/2066). After adjusting for hypertension (HTN), the total prevalence was 0.5% (8/1457). In a subgroup analysis, 551 teenagers with documented race and LV wall thickness were identified between the ages of 13 - 19 years. African American teenagers 6% (3/50)] had higher prevalence of suspected HCM 0.8% (4/501), OR 7.93, CI 1.72-36.49, p = 0.002]. After multivariate adjustment for age, gender, BMI and HTN (systolic BP >140 and diastolic BP of > 90), African American race remained independently associated with suspected HCM (OR 4.89, CI 1.24-39.62, p = 0.02).CONCLUSION:The prevalence of suspected HCM in young teenagers is approximately 0.2%. This prevalence appears to be higher in African Americans. However, due to small number of African Americans in our population, our result needs to be confirmed in larger trials.This item is part of the UA Faculty Publications collection. For more information this item or other items in the UA Campus Repository, contact the University of Arizona Libraries at [email protected]

Density stratification and turbulent mixing in a salt-wedge estuary: The Adour river

HydrodynamicsAbstrac