Dietary dairy product intake and incident type 2 diabetes: a prospective study using dietary data from a 7-day food diary

The consumption of specific dairy types may be beneficial for the prevention of diabetes. Abstract: The aim of this study was to investigate the association between total and types of dairy product intake and risk of developing incident type 2 diabetes, using a food diary. Methods: A nested case-cohort within the EPIC-Norfolk Study was examined, including a random subcohort (n=4,000) and cases of incident diabetes (n=892, including 143 cases in the subcohort) followed-up for 11 years. Diet was assessed using a prospective 7-day food diary. Total dairy intake (g/day) was estimated and categorised into high-fat (≥3.9%) and low-fat (<3.9% fat) dairy, and by subtype into yoghurt, cheese and milk. Combined fermented dairy product intake (yoghurt, cheese, sour cream) was estimated and categorised into high- and low-fat. Prentice-weighted Cox regression HRs were calculated. Results: Total dairy, high-fat dairy, milk, cheese and high-fat fermented dairy product intakes were not associated with the development of incident diabetes. Low-fat dairy intake was inversely associated with diabetes in age- and sex-adjusted analyses (tertile [T] 3 vs T1, HR 0.81 [95% CI 0.66, 0.98]), but further adjustment for anthropometric, dietary and diabetes risk factors attenuated this association. In addition, an inverse association was found between diabetes and low-fat fermented dairy product intake (T3 vs T1, HR 0.76 [95% CI 0.60, 0.99]; ptrend=0.049) and specifically with yoghurt intake (HR 0.72 [95% CI 0.55, 0.95]; ptrend=0.017) in multivariable adjusted analyses. Conclusions/interpretation: Greater low-fat fermented dairy product intake, largely driven by yoghurt intake, was associated with a decreased risk of type 2 diabetes development in prospective analyses. These findings suggest that the consumption of specific dairy types may be beneficial for the prevention of diabetes, highlighting the importance of food group subtypes for public health messages

Reconstructing the World of the Anorectic Outpatient: Procedures for Enhancing Trustworthiness and Credibility

Conducting in-depth interviews with clinical populations often poses a number of problems for qualitative researchers. Because of the skewed perception of themselves and the world around them, and because of their propensity to distort and deny the pathology of their illness, anorexic women are an example of one such group that can create possible problems for researchers, particularly those concerned with the trustworthiness and credibility of their analysis. How should qualitative researchers approach this population? How can a credible reconstruction of reality be produced? This paper explores and discusses the procedures utilized by the authors during an 18-month project in which semi-structured, ethnographic interviews were conducted with 28 outpatients at an eating disorder treatment facility. This paper describes the methods employed by the authors to enhance the epistemological authority and trustworthiness of the analysis. These included: 1) a multi-disciplinary team approach with researchers and consultants from mass communication, family science, and clinical psychology, 2) weekly researcher team debriefing sessions to analyze and interpret recently completed interviews, 3) the exchange of thoughts and ideas from researcher diaries, journals, and coding memos, 4) the use of recovered anorexic patients as research assistants to help in the interpretation of interviews and to perform member checks, and 5) periodic debriefing sessions with therapists at the center where the project\u27s informants were being treated

Verschuivende verhoudingen

Overgewicht is in relatief korte tijd veranderd van een individueel gezondheidsprobleem in een volksgezondheidsprobleem. Dit is gepaard gegaan met een groeiende roep om overheidsbemoeienis in de vorm van wet- en regelgeving. Maar wat vermag de overheid? In dit essay onderwerpen we de roep om overheidsingrijpen aan een kritische reflectie. Hoewel de overheid een grondwettelijke verantwoordelijkheid heeft voor de publieke gezondheid, leert de geschiedenis van andere leefstijlgerelateerde problemen ons dat de overheid zich in een paradoxale situatie bevindt. Enerzijds kan ze in instrumentele zin veel doen – ze beschikt immers over een uitgebreide gereedschapskist met juridische en economische beleidsinstrumenten. Anderzijds wordt de overheid vaak in haar handelingsruimte beperkt doordat dat beleidsinstrumentarium maatschappelijk omstreden is

FREEZE! A manifesto for safeguarding and preserving born-digital heritage

Finding ways to preserve born-digital heritage has become a matter of urgency and growing concern. Websites, games and interactive documentaries each bring specific challenges that need to be addressed. It takes three to tango: Ensuring that our digital lives and digital creativity are not lost to future generations requires a joint effort by the principal players: creators, heritage professionals and policy makers. This manifesto lays out the actions they need to take today to safeguard born-digital heritage

Investigating Different Levels of Bimanual Interaction With a Novel Motor Learning Task: A Behavioural and Transcranial Alternating Current Stimulation Study

Many tasks require the skilled interaction of both hands, such as eating with knife and fork or keyboard typing. However, our understanding of the behavioural and neurophysiological mechanisms underpinning bimanual motor learning is still sparse. Here, we aimed to address this by first characterising learning-related changes of different levels of bimanual interaction and second investigating how beta tACS modulates these learning-related changes. To explore early bimanual motor learning, we designed a novel bimanual motor learning task. In the task, a force grip device held in each hand (controlling x- and y-axis separately) was used to move a cursor along a path of streets at different angles (0°, 22.5°, 45°, 67.5°, and 90°). Each street corresponded to specific force ratios between hands, which resulted in different levels of hand interaction, i.e., unimanual (Uni, i.e., 0°, 90°), bimanual with equal force (Bieq, 45°), and bimanual with unequal force (Biuneq 22.5°, 67.5°). In experiment 1, 40 healthy participants performed the task for 45 min with a minimum of 100 trials. We found that the novel task induced improvements in movement time and error, with no trade-off between movement time and error, and with distinct patterns for the three levels of bimanual interaction. In experiment 2, we performed a between-subjects, double-blind study in 54 healthy participants to explore the effect of phase synchrony between both sensorimotor cortices using tACS at the individual’s beta peak frequency. The individual’s beta peak frequency was quantified using electroencephalography. 20 min of 2 mA peak-to-peak amplitude tACS was applied during task performance (40 min). Participants either received in-phase (0° phase shift), out-of-phase (90° phase shift), or sham (3 s of stimulation) tACS. We replicated the behavioural results of experiment 1, however, beta tACS did not modulate motor learning. Overall, the novel bimanual motor task allows to characterise bimanual motor learning with different levels of bimanual interaction. This should pave the way for future neuroimaging studies to further investigate the underlying mechanism of bimanual motor learning