2,423 research outputs found
A phenomenal basis for hybrid modelling
This work in progress extends the new mechanical philosophy from science to engineering. Engineering is the practice of organising the design and construction of artifices that satisfy needs in real-world contexts. This work shows how artifices can be described in terms of their mechanisms and composed through their observable phenomena.
Typically, the engineering of real system requires descrip- tions in many different languages: software components will be described in code; sensors and actuators in terms of their physical and electronic characteristics; plant in terms of differ- ential equations, perhaps. Another aspect of this work, then, to construct a formal framework so that diverse description languages can be used to characterise sub-mechanisms.
The work is situated in Problem Oriented Engineering, a design theoretic framework engineering defined by the first two authors
On the possibilities of large-scale radio and fiber optics detectors in cosmic rays
Different variants of radio and fiber optics detectors for registration of super high energy cascades in the atmosphere and in dense media are discussed. Particularly the possibilities for investigation of quasi horizontal cosmic ray showers (CRS) and simulated muons from these CRS with the help of radio detectors and fiber optics detectors located on the ice surface are considered
Tight junction physiology of pleural mesothelium
Pleura consists of visceral and parietal cell layers, producing a fluid, which
is necessary for lubrication of the pleural space. Function of both
mesothelial cell layers is necessary for the regulation of a constant pleural
fluid volume and composition to facilitate lung movement during breathing.
Recent studies have demonstrated that pleural mesothelial cells show a
distinct expression pattern of tight junction proteins which are known to
ubiquitously determine paracellular permeability. Most tight junction proteins
provide a sealing function to epithelia, but some have been shown to have a
paracellular channel function or ambiguous properties. Here we provide an in-
depth review of the current knowledge concerning specific functional
contribution of these proteins determining transport and barrier function of
pleural mesothelium
CONSIDERATIONS ON THE INCIDENCE AND WIDESPREADING OF DISSEMINATED SCLEROSIS IN THE DISTRICT OF VARNA
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