Kontrola parametara tehničkog sistema za navodnjavanje kap- po-kap

The parameters of the technical system that is used for controlling drip irrigation systems, in production conditions, has been shown thru the DREAM system, produce by TALGIL Computing and Control, Haifa, Israel. Performances of the drip irrigation technical system, the DREAM system is controlling by automatic mode which is being program ahead, and it is enabling the control for few features parameters needed for water application, and as well and work regimes of: pumps, filters, water meters, main and secondary valves. This system of control is used in Delta Agrar orchard in Celarevo, and already for five years, based on his capabilities, the most difficult tasks has been completed or specified with great sexes. Beside the mention features, very important feature and often used, is the feature of reading data that are been collected over the whole period of exploitation, such as: total water apply water, total follow of the main valve, total flow of the secondary valves, total mineral fertilizer apply, etc. This system of the automatic control, is the newest in the “TALGIL Computing and Control” Israel, pallet of product, and its subliming all the adventives, that are throe the time, have been shown as the most practical.Kontrola upravljanja parametrima tehničkog sistema sistemom kap-po-kap, za proizvodne uslove prikazana je osobinama uređaja DREAM sistem, proizvođača - TALGIL Computing and Control , Haifa, Israel. Performanse tehničkog sistema kap-po-kap, DREAM sistem kotroliše automatskim režimom rada koji se unapred programira i omogućava kontrolu rada nekoliko parametara potrebnih za efikasnu distribuciju vode, pre svega režima rada: pumpi, filtera, merača protoka, glavnih i sekundarnih ventila. Ovakav jedan sistem automatskog upravljanja koristi se u voćnjaku Delta Agrara u Čelarevu. Već 5 godina na osnovu njegovih mogućnosti uspešno se realizuju najteži zahtevi intenzivne proizvodnje. Pored mogućnosti programiranja i upravljanja, jako je važna i veoma se često koristi očitavanje podatka sakupljenih tokom kompletnog-određenog perioda ekploatacije, kao što su: ukupna količina aplicirane vode, ukupan protok glavnog ventila, ukupan protok sekundarnih ventila, ukupna količina apliciranih mineralnih đubriva, itd. Ovaj sistem automatskog upravljanja je najnoviji u nizu proizvoda kompanije - TALGIL Computing and Control, i sublimira mnoge prednosti koje su se kroz period razvoja automatske kontrole uopšte, pokazale kao praktične i primenljive u praksi

The Thermal Behaviour of a Cylindrical Air Layer Enclosed between Double Fabric Roof Membranes

Objects covered by fabric roof membranes are specific in terms of energy consumption, primarily because of the negligible thickness of the material and its good thermal conduction properties. One of the ways of improving the energy efficiency of these objects is the implementation of a double fabric roof membrane structure with an enclosed non ventilated air layer. This paper analyzes the thermal-insulation behaviour of the air layer enclosed between tensile fabric roof membranes which are used for structural purposes. The compilation of the necessary data was carried out by measuring a real object covered by a double fabric roof membrane, semi-cylindrical in shape. The surface temperatures of each membrane were measured, as were the outside and inside air temperature and the air temperature between the membranes during the summer months. In addition, the solar irradiance during the same period was also measured. The analysis of the measured data took into consideration all the present forms of energy transmittance (convection, conduction and radiation), as well as the shape of the air layer and the thermal-physical specific features of border surfaces. The results of the study indicate that thermal behaviour of a closed semi-cylindrical air layer depends on the real outer conditions in the summer months. A methodological approach to the thermal modelling of these structures has accordingly been proposed

IMPACT OF TROMBE WALL CONSTRUCTION ON THERMAL COMFORT AND BUILDING ENERGY CONSUMPTION

Energy consumption has reached its highest level globally. Buildings have the largest share in total energy consumption, so we must take into account their functioning and the consequences that can arise. Passive solar design is an imperative in modern architecture, and Trombe wall, as one of the principles of this design, is certainly distinguished. The paper presents an overview of the characteristics of the construction of the Trombe Wall in order to improve thermal stability and reduce energy consumption in buildings. Starting from the consideration of climatic influencing factors, through the heat capacity of the materials applied and their thickness and color of the thermal mass, it is very important to know in detail all the factors that can lead to the improvement of the efficiency of this system. The specific heat of the walls in the building, the time delay, the decrement factor and the influence and position of the thermal insulation were also taken into account. The effect of glazing as well as the influence of the ventilation openings were highlighted as significant elements. On the basis of the analysis of the above components, the conclusions and guidelines for designing this type of constructions were made in order to improve the efficiency and reduced energy consumption while providing adequate comfort in the facility

A block to pre-prepared movement in gait freezing, relieved by pedunculopontine nucleus stimulation

Gait freezing and postural instability are disabling features of Parkinsonian disorders, treatable with pedunculopontine nucleus stimulation. Both features are considered deficits of proximal and axial musculature, innervated predominantly by reticulospinal pathways and tend to manifest when gait and posture require adjustment. Adjustments to gait and posture are amenable to pre-preparation and rapid triggered release. Experimentally, such accelerated release can be elicited by loud auditory stimuli—a phenomenon known as ‘StartReact’. We observed StartReact in healthy and Parkinsonian controls. However, StartReact was absent in Parkinsonian patients with severe gait freezing and postural instability. Pedunculopontine nucleus stimulation restored StartReact proximally and proximal reaction times to loud stimuli correlated with gait and postural disturbance. These findings suggest a relative block to triggered, pre-prepared movement in gait freezing and postural instability, relieved by pedunculopontine nucleus stimulation

Alpha oscillations in the pedunculopontine nucleus correlate with gait performance in parkinsonism

The pedunculopontine nucleus, a component of the reticular formation, is topographically organized in animal models and implicated in locomotor control. In Parkinson's disease, pedunculopontine nucleus stimulation is an emerging treatment for gait freezing. Local field potentials recorded from pedunculopontine nucleus electrodes in such patients have demonstrated oscillations in the alpha and beta frequency bands, reactive to self-paced movement. Whether these oscillations are topographically organized or relevant to locomotion is unknown. Here, we recorded local field potentials from the pedunculopontine nucleus in parkinsonian patients during rest and unconstrained walking. Relative gait speed was assessed with trunk accelerometry. Peaks of alpha power were present at rest and during gait, when they correlated with gait speed. Gait freezing was associated with attenuation of alpha activity. Beta peaks were less consistently observed across rest and gait, and did not correlate with gait speed. Alpha power was maximal in the caudal pedunculopontine nucleus region and beta power was maximal rostrally. These results indicate a topographic distribution of neuronal activity in the pedunculopontine nucleus region and concur with animal data suggesting that the caudal subregion has particular relevance to gait. Alpha synchronization, proposed to suppress ‘task irrelevant’ distraction, has previously been demonstrated to correlate with performance of cognitive tasks. Here, we demonstrate a correlation between alpha oscillations and improved gait performance. The results raise the possibility that stimulation of caudal and rostral pedunculopontine nucleus regions may differ in their clinical effects

Quantum interference of electromechanically stabilized emitters in nanophotonic devices

Photon-mediated coupling between distant matter qubits may enable secure communication over long distances, the implementation of distributed quantum computing schemes, and the exploration of new regimes of many-body quantum dynamics. Nanophotonic devices coupled to solid-state quantum emitters represent a promising approach towards realization of these goals, as they combine strong light-matter interaction and high photon collection efficiencies. However, the scalability of these approaches is limited by the frequency mismatch between solid-state emitters and the instability of their optical transitions. Here we present a nano-electromechanical platform for stabilization and tuning of optical transitions of silicon-vacancy (SiV) color centers in diamond nanophotonic devices by dynamically controlling their strain environments. This strain-based tuning scheme has sufficient range and bandwidth to alleviate the spectral mismatch between individual SiV centers. Using strain, we ensure overlap between color center optical transitions and observe an entangled superradiant state by measuring correlations of photons collected from the diamond waveguide. This platform for tuning spectrally stable color centers in nanophotonic waveguides and resonators constitutes an important step towards a scalable quantum network

Exercise response in Parkinson’s Disease : insights from a cross-sectional comparison with sedentary controls and a per protocol analysis of a randomised controlled trial

Objectives: To investigate the acute and adaptation cardiovascular and metabolic training responses in people with Parkinson’s (pwP). Design: 1) A cross sectional study of exercise response of pwP compared to sedentary controls,2) an interventional study of exercise training in pwP. Setting: Community leisure facilities. Participants: pwP (n=83) & sedentary controls (n=55) Interventions: Study (1) included participants from a two arm parallel single blind phase II Randomised Controlled Trial (RCT), that undertook a baseline maximal incremental exercise test and study (2) included those randomised to the exercise group in the RCT, who completed a six-month weekly exercise programme (n=37). The intervention (study (2) was a prescribed exercise program consisting of sessions lasting 60 minutes, twice a week over a six-month period. The control group followed the same protocol which derived the same cardio respiratory parameters, except the they were instructed to aim for a cadence of ~60rpm and the unloaded phase lasted 3minutes with an initial step of 25watts. Primary and secondary outcome measures: Stepwise incremental exercise test to volitional exhaustion was the primary outcome measure. Results: Study (1) showed higher maximum values for heart rate, VO2l.min-1, VCO2l.min-1 and Ventilation l.min-1 for the control group; Respiratory Exchange Ratio (RER), perceived exertion and O2 Pulse (VO2l.min-1/ HR) did not differ between groups. In study (2), for pwP who adhered to training (n=37), RER increased significantly and although there was no significant change in aerobic capacity or heart rate response, reduced blood pressure was found. Conclusions: An abnormal cardiovascular response to exercise was observed in pwP compared to controls. After the exercise programme, metabolic deficiencies remained for pwP. These observations add to the pathogenic understanding of PD, acknowledge an underling metabolic contribution and support that certain cardiovascular symptoms may improve as a result of this type of exercise Trial registration: ClinicalTrials.Gov (NCT01439022)

Cerebral Structure and Function in Myotonic Dystrophy

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Precision Medicine for Hepatocellular Carcinoma: Clinical Perspective

Hepatocellular carcinoma (HCC) is one of the major malignant diseases worldwide, characterized by growing incidence and high mortality rates despite apparent improvements in surveillance programs, diagnostic and treatment procedures, molecular therapies, and numerous research initiatives. Most HCCs occur in patients with liver cirrhosis, and the competing mortality risks from the tumor and the cirrhosis should be considered. Presently, previously identified risk factors, such as hepatitis virus infection, hepatic inflammation and fibrosis, and metabolic syndrome, may be used as chemoprevention targets. The application of precision medicine for HCC management challenges the one-size-fits-all concept; moreover, patients should no longer be treated entirely according to the histology of their tumor but based on molecular targets specific to their tumor biology. Next-generation sequencing emphasizes HCC molecular heterogeneity and aids our comprehension of possible vulnerabilities that can be exploited. Moreover, genetic sequencing as part of a precision medicine concept may work as a promising tool for postoperative cancer monitoring. The use of genetic and epigenetic markers to identify therapeutic vulnerability could change the diagnosis and treatment of HCC, which so far was based on Barcelona clinic liver cancer (BCLC) staging. In daily clinical practice, the shift from a stage-oriented to a therapeutic-oriented approach is needed to direct the choice of HCC treatment toward the potentially most effective option on an individual basis. The important factor in precision medicine is the promotion of patient management based on the individual approach, knowing that the final decision must be approved by a multidisciplinary expert team