Cell Ablation in Transgenic Mice

The toxigcne approach. in which the toxic gene product is guided by the cell specific promoter to the desired tissue. is an effective way of ablating cells both in germline transgenic mice and also in somatic transgenic tissues. It opens up new possibilities for physiological and cell lineage studies and gene therapy of tumors. The more effective targeting of toxigcnes into the genome and timing of their expression will further increase their applicability

Kanojen yleiseen sairaudenvastustuskykyyn liittyviä tekijöitä

VKirjasto Aj-

Preimplantation Genetic Diagnosis in cattle: A review

Preimplantation Genetic Diagnosis (PGD) is reviewed and novel fields where it may be applied are investigated. Technical advances of PGD in cattle embryos have already enabled its integration as a part of the MOET (Multiple Ovulation Embryo Transfer) breeding system. PGD for well-defined selection targets can enhance cattle breeding and embryo trade. It allows embryo selection according to their sex, and it may be used to breed special cow lines, or top bulls, by selecting embryos for valuable production traits using Marker Assisted Selection (MAS). A good allelic profile and/or the insertion of a transgene can be detected by PGD. This review article presents the technical requirements for PGD, and shows that this biotechnological method has great economic potential

Huuruava kylmyys säilyttää elämää

vokKirjasto Aj-

MHC haplotypes of white leghorn hens for production traits. Finnish part of a Scandinavian experiment

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Alkiotuotannon ja -tutkimuksen nykytila ja tavoitteet ASMO-ydinkarjahankkeessa

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Keinohedelmöityksen mahdollisuudet ja tutkimus naudalla

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