489 research outputs found
Latino Protestants and Their Political and Social Engagement (Chapter Six of Latino Protestants in America: Growing and Diverse)
Excerpt: On a rainy early spring morning in a modest brick Presbyterian church just outside the Fruitvale neighborhood of Oakland, California, sixtyfour worshippers gather. The entire worship is in Spanish. During the sermon, the pastor makes a passing reference to how few of the attenders now live in Oakland proper, that many have to drive farther than ever for church services. The implicit message: the leadership of the church realizes that gentrification of San Francisco has spilled over the Bay Bridge and now threatens the availability of affordable housing throughout Oakland. In response, the congregation has started programs that offer legal advice for responding to rent-hiking landlords and identifying housing options around the city. Though resources and attenders tend to be somewhat scarce, the leadership has creatively organized in an effort to address the structural and policy concerns of housing. Beyond that, the pastor proudly notes that this church readily offers immigration status services, computer classes, and English classes
Relationship between depressive symptom severity and emergency department use among low-income, depressed homebound older adults aged 50 years and older
Namkee G. Choi, and C. Nathan Marti are with The University of Texas at Austin, Austin, TX, USA. -- Martha L. Bruce is with the Weill Cornell Medical College, White Plains, NY, USA. -- Mark E. Kunik is with the VA HSRD Houston Center of Excellence, Michael E. DeBakey VA Medical Center, Houston, TX, USA, and Baylor College of Medicine, Houston, TX, USA, and VA South Central Mental Illness Research, Education and Clinical Center, Houston, TX, USA.Background: Previous research found a high prevalence of depression, along with chronic illnesses and disabilities, among older ED patients. This study examined the relationship between depressive symptom severity and the number of ED visits among low-income homebound older adults who participated in a randomized controlled trial of telehealth problem-solving therapy (PST).
Methods: The number of and reasons for ED visits were collected from the study participants (n=121 at baseline) at all assessment points—baseline and 12- and 24-week follow-ups. Depressive symptoms were measured with the 24-item Hamilton Rating Scale for Depression (HAMD). All multivariable analyses examining the relationships between ED visits and depressive symptoms were conducted using zero-inflated Poisson regression models.
Results: Of the participants, 67.7% used the ED at least once and 61% of the visitors made at least one return visit during the approximately 12-month period. Body pain (not from fall injury and not including chest pain) was the most common reason. The ED visit frequency at baseline and at follow-up was significantly positively associated with the HAMD scores at the assessment points. The ED visit frequency at follow-up, controlling for the ED visits at baseline, was also significantly associated with the HAMD score change since baseline.
Conclusions: The ED visit rate was much higher than those reported in other studies. Better education on self-management of chronic conditions, depression screening by primary care physicians and ED, and depression treatment that includes symptom management and problem-solving skills may be important to reduce ED visits among medically ill, low-income homebound adults.
Trial registration
ClinicalTrials.gov Identifier: NCT00903019Psycholog
Nutrition Controls Mitochondrial Biogenesis in the Drosophila Adipose Tissue through Delg and Cyclin D/Cdk4
Mitochondria are cellular organelles that perform critical metabolic functions: they generate energy from nutrients but also provide metabolites for de novo synthesis of fatty acids and several amino acids. Thus mitochondrial mass and activity must be coordinated with nutrient availability, yet this remains poorly understood. Here, we demonstrate that Drosophila larvae grown in low yeast food have strong defects in mitochondrial abundance and respiration activity in the larval fat body. This correlates with reduced expression of genes encoding mitochondrial proteins, particularly genes involved in oxidative phosphorylation. Second, genes involved in glutamine metabolism are also expressed in a nutrient-dependent manner, suggesting a coordination of amino acid synthesis with mitochondrial abundance and activity. Moreover, we show that Delg (CG6338), the Drosophila homologue to the alpha subunit of mammalian transcription factor NRF-2/GABP, is required for proper expression of most genes encoding mitochondrial proteins. Our data demonstrate that Delg is critical to adjust mitochondrial abundance in respect to Cyclin D/Cdk4, a growth-promoting complex and glutamine metabolism according to nutrient availability. However, in contrast to nutrients, Delg is not involved in the regulation of mitochondrial activity in the fat body. These findings are the first genetic evidence that the regulation of mitochondrial mass can be uncoupled from mitochondrial activity
Humanities in Predoctoral Dental Education: A Scoping Review
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/153732/1/jddjde019126.pd
The Role of Modality in Developing Durable Skills: Challenges and Experiences of Diverse Student Populations
The efficacy and benefits of various modalities for teaching and learning have been fiercely debated since the pandemic. In general, disciplines that are content-laden and could be taught primarily through passive learning strategies (reading and lecturing) fared better with the transition to distance and online learning. There was great skepticism about the ability to have the same engagement and learning outcomes met in asynchronous design for more applied and interactive disciplines, especially when considering the development of durable skills. Although market researchers have found that employers desire durable skills (formerly “soft skills”), few studies have been dedicated to identifying where, when, and how course modality plays a role in fostering such skill sets. This study proposes to investigate how modality contributes to or inhibits the development of durable skills and identify strategies for addressing challenges that different student populations face given their manner of course participation and attendance while in college. Results from the study indicate that commuters, first-generation, online, and graduate students, given the manner of their engagement with co-curricular and extracurricular activities, are at a disadvantage, requiring new strategies for skills development
Insight into D6h symmetry: targeting strong axiality in stable dysprosium(III) hexagonal bipyramidal single-ion magnets
Following a novel synthetic strategy where the strong uniaxial ligand field generated by the Ph3SiO− (Ph3SiO−=anion of triphenylsilanol) and the 2,4‐di‐tBu‐PhO− (2,4‐di‐tBu‐PhO−=anion of 2,4‐di‐tertbutylphenol) ligands combined with the weak equatorial field of the ligand LN6, leads to [DyIII(LN6)(2,4‐di‐tBu‐PhO)2](PF6) (1), [DyIII(LN6)(Ph3SiO)2](PF6) (2) and [DyIII(LN6)(Ph3SiO)2](BPh4) (3) hexagonal bipyramidal dysprosium(III) single‐molecule magnets (SMMs) with high anisotropy barriers of Ueff=973 K for 1, Ueff=1080 K for 2 and Ueff=1124 K for 3 under zero applied dc field. Ab initio calculations predict that the dominant magnetization reversal barrier of these complexes expands up to the 3rd Kramers doublet, thus revealing for the first time the exceptional uniaxial magnetic anisotropy that even the six equatorial donor atoms fail to negate, opening up the possibility to other higher‐order symmetry SMMs
Insight into D6h symmetry: targeting strong axiality in stable dysprosium(III) hexagonal bipyramidal single-ion magnets
Following a novel synthetic strategy where the strong uniaxial ligand field generated by the Ph3SiO− (Ph3SiO−=anion of triphenylsilanol) and the 2,4‐di‐tBu‐PhO− (2,4‐di‐tBu‐PhO−=anion of 2,4‐di‐tertbutylphenol) ligands combined with the weak equatorial field of the ligand LN6, leads to [DyIII(LN6)(2,4‐di‐tBu‐PhO)2](PF6) (1), [DyIII(LN6)(Ph3SiO)2](PF6) (2) and [DyIII(LN6)(Ph3SiO)2](BPh4) (3) hexagonal bipyramidal dysprosium(III) single‐molecule magnets (SMMs) with high anisotropy barriers of Ueff=973 K for 1, Ueff=1080 K for 2 and Ueff=1124 K for 3 under zero applied dc field. Ab initio calculations predict that the dominant magnetization reversal barrier of these complexes expands up to the 3rd Kramers doublet, thus revealing for the first time the exceptional uniaxial magnetic anisotropy that even the six equatorial donor atoms fail to negate, opening up the possibility to other higher‐order symmetry SMMs
Sponge-Like Behaviour in Isoreticular Cu(Gly-His-X) Peptide-Based Porous Materials
We report two isoreticular 3D peptide-based porous frameworks formed by coordination of the tripeptides Gly-l-His-Gly and Gly-l-His-l-Lys to Cu(II) which display sponge-like behaviour. These porous materials undergo structural collapse upon evacuation that can be reversed by exposure to water vapour, which permits recovery of the original open channel structure. This is further confirmed by sorption studies that reveal that both solids exhibit selective sorption of H(2)O while CO(2) adsorption does not result in recovery of the original structures. We also show how the pendant aliphatic amine chains, present in the framework from the introduction of the lysine amino acid in the peptidic backbone, can be post-synthetically modified to produce urea-functionalised networks by following methodologies typically used for metal–organic frameworks built from more rigid “classical” linkers
Suzaku Observations of the Galactic Center Microquasar 1E 1740.7-2942
We present two Suzaku observations of the Galactic center microquasar 1E
1740.7-2942 separated by approximately 700 days. The source was observed on
both occasions after a transition to the spectrally hard state. Significant
emission from 1E 1740.7-2942 is detected out to an energy of 300 keV, with no
spectral break or turnover evident in the data. We tentatively measure a lower
limit to the cut-off energy of ~ 380 keV. The spectra are found to be
consistent with a Comptonized corona on both occasions, where the high energy
emission is consistent with a hard power-law (\Gamma ~ 1.8) with a significant
contribution from an accretion disc with a temperature of ~ 0.4 keV at soft
X-ray energies. The measured value for the inner radius of the accretion disc
is found to be inconsistent with the picture whereby the disc is truncated at
large radii in the low-hard state and instead favours a radius close to the
ISCO (R_in ~ 10 - 20 R_g).Comment: 8 pages, 4 figures, formatted using emulateapj.cls. Accepted for
publication in Ap
Renormalization of Supersymmetric Gauge Theories on Orbifolds: Brane Gauge Couplings and Higher Derivative Operators
We consider supersymmetric gauge theories coupled to hyper multiplets on five
and six dimensional orbifolds and determine the bulk and local fixed point
renormalizations of the gauge couplings. We infer from a component analysis
that the hyper multiplet does not induce renormalization of the brane gauge
couplings on the five dimensional orbifold S^1/Z_2. This is not due to
supersymmetry, since the bosonic and fermionic contributions cancel separately.
We extend this investigation to T^2/Z_N orbifolds using supergraph techniques
in six dimensions. On general Z_N orbifolds the gauge couplings do renormalize
at the fixed points, except for the Z_2 fixed points of an even ordered
orbifold. To cancel the bulk one-loop divergences a dimension six higher
derivative operator is needed, in addition to the standard bulk gauge kinetic
term.Comment: 10 p
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