Cosmic Superstring Scattering in Backgrounds

We generalize the calculation of cosmic superstring reconnection probability to non-trivial backgrounds. This is done by modeling cosmic strings as wound tachyon modes in the 0B theory, and the spacetime effective action is then used to couple this to background fields. Simple examples are given including trivial and warped compactifications. Generalization to $(p,q)$ strings is discussed.Comment: 12 pages, 2 figures; v2: references adde

Two Black Hole Holography, Lensing and Intensity

We numerically verify the analysis of the "expanding horizon" theory of Susskind in relation to the 't Hooft holographic conjecture. By using a numerical simulation to work out the image formed by two black holes upon a screen very far away, it is seen that it is impossible for a horizon to hide behind another. We also compute the intensity distribution of such an arrangement.Comment: 10 page

Interactions of Cosmic Superstrings

We develop methods by which cosmic superstring interactions can be studied in detail. These include the reconnection probability and emission of radiation such as gravitons or small string loops. Loop corrections to these are discussed, as well as relationships to $(p,q)$-strings. These tools should allow a phenomenological study of string models in anticipation of upcoming experiments sensitive to cosmic string radiation.Comment: 22 pages, 6 figures; v2: updated reference

Cooling of cryogenic electron bilayers via the Coulomb interaction

Heat dissipation in current-carrying cryogenic nanostructures is problematic because the phonon density of states decreases strongly as energy decreases. We show that the Coulomb interaction can prove a valuable resource for carrier cooling via coupling to a nearby, cold electron reservoir. Specifically, we consider the geometry of an electron bilayer in a silicon-based heterostructure, and analyze the power transfer. We show that across a range of temperatures, separations, and sheet densities, the electron-electron interaction dominates the phonon heat-dissipation modes as the main cooling mechanism. Coulomb cooling is most effective at low densities, when phonon cooling is least effective in silicon, making it especially relevant for experiments attempting to perform coherent manipulations of single spins.Comment: 9 pages, 5 figure

Gravitational Wave Bursts from Cosmic Superstring Reconnections

We compute the gravitational waveform produced by cosmic superstring reconnections. This is done by first constructing the superstring reconnection trajectory, which closely resembles that of classical, instantaneous reconnection but with the singularities smoothed out due to the string path integral. We then evaluate the graviton vertex operator in this background to obtain the burst amplitude. The result is compared to the detection threshold for current and future gravitational wave detectors, finding that neither bursts nor the stochastic background would be detectable by Advanced LIGO. This disappointing but anticipated conclusion holds even for the most optimistic values of the reconnection probability and loop sizes.Comment: 26 pages, 6 figures; v2: references added and typos correcte

Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis

During interkinesis, a metaphase II (MetII) spindle is built immediately after the completion of meiosis I. Oocytes then remain MetII arrested until fertilization. In mouse, we find that early mitotic inhibitor 2 (Emi2), which is an anaphase-promoting complex inhibitor, is involved in both the establishment and the maintenance of MetII arrest. In MetII oocytes, Emi2 needs to be degraded for oocytes to exit meiosis, and such degradation, as visualized by fluorescent protein tagging, occurred tens of minutes ahead of cyclin B1

iRFP is a real time marker for transformation based assays in high content screening

Anchorage independent growth is one of the hallmarks of oncogenic transformation. Here we show that infrared fluorescent protein (iRFP) based assays allow accurate and unbiased determination of colony formation and anchorage independent growth over time. This protocol is particularly compatible with high throughput systems, in contrast to traditional methods which are often labor-intensive, subjective to bias and do not allow further analysis using the same cells. Transformation in a single layer soft agar assay could be documented as early as 2 to 3 days in a 96 well format, which can be easily combined with standard transfection, infection and compound screening setups to allow for high throughput screening to identify therapeutic targets

Vibrational signatures for low-energy intermediate-sized Si clusters

We report low-energy locally stable structures for the clusters Si20 and Si21. The structures were obtained by performing geometry optimizations within the local density approximation. Our calculated binding energies for these clusters are larger than any previously reported for this size regime. To aid in the experimental identification of the structures, we have computed the full vibrational spectra of the clusters, along with the Raman and IR activities of the various modes using a recently developed first-principles technique. These represent, to our knowledge, the first calculations of Raman and IR spectra for Si clusters of this size

Cold Nuclear Matter In Holographic QCD

We study the Sakai-Sugimoto model of holographic QCD at zero temperature and finite chemical potential. We find that as the baryon chemical potential is increased above a critical value, there is a phase transition to a nuclear matter phase characterized by a condensate of instantons on the probe D-branes in the string theory dual. As a result of electrostatic interactions between the instantons, this condensate expands towards the UV when the chemical potential is increased, giving a holographic version of the expansion of the Fermi surface. We argue based on properties of instantons that the nuclear matter phase is necessarily inhomogeneous to arbitrarily high density. This suggests an explanation of the "chiral density wave" instability of the quark Fermi surface in large N_c QCD at asymptotically large chemical potential. We study properties of the nuclear matter phase as a function of chemical potential beyond the transition and argue in particular that the model can be used to make a semi-quantitative prediction of the binding energy per nucleon for nuclear matter in ordinary QCD.Comment: 31 pages, LaTeX, 1 figure, v2: some formulae corrected, qualitative results unchange

Molecular structures and vibrations of neutral and anionic CuOx (x = 1-3,6) clusters

We report equilibrium geometric structures of CuO2, CuO3, CuO6, and CuO clusters obtained by an all-electron linear combination of atomic orbitals scheme within the density-functional theory with generalized gradient approximation to describe the exchange-correlation effects. The vibrational stability of all clusters is examined on the basis of the vibrational frequencies. A structure with Cs symmetry is found to be the lowest-energy structure for CuO2, while a -shaped structure with C2v symmetry is the most stable structure for CuO3. For the larger CuO6 and CuO clusters, several competitive structures exist with structures containing ozonide units being higher in energy than those with O2 units. The infrared and Raman spectra are calculated for the stable optimal geometries. ~Comment: Uses Revtex4, (Better quality figures can be obtained from authors