The compulation and classification of physical fitness, motor ability, and sports skills tests in physical education.

Thesis (Ed.M.)--Boston Universit

Neighbors of knots in the Gordian graph

We show that every knot is one crossing change away from a knot of arbitrarily high bridge number and arbitrarily high bridge distance.Comment: Accepted by American Mathematical Monthly. New version incorporates referee comment

The Ursinus Weekly, March 13, 1944

Girls grab gobs for gala gathering as leap-year Lorelei looms at last • Y will entertain at spring reception • Students sell $13,744.70 in war bond drive as Eileen Smith wins second individual prize • Dr. W. Fuller explains CED work after war • Rex Gregor is awarded silver star for bravery • Chaplain tells students progress is inevitable • Senators to direct Red Cross drive here • Curtain Club to give three one-act plays • Marian Martin becomes IRC secretary-treasurer • Freshmen to receive colors in ceremony on Thursday • World Student Service Fund helps Chinese students solve problems • Delegates to be chosen for Penn State conference • Coeds to hear Mrs. Mooney • Carpenters, painters give new face to rec center • Dr. Oppenheimer speaks to pre-medical society • Lt. Norris A. Johnson \u2736, Navy radioman, writes from southwest Pacific about Air Corps duties • Frosh end sorority blues • Loyal Irish to praise St. Patrick on Friday • Improved girls\u27 team upsets Beaver after deadlocking for three periods • J.V.\u27s take Jenkintown six; Mid Halbruegge sets pace • Baseball team practices indoors under Heffernan • One-act play will be given at Women\u27s Club session • Betty Tyson reviews poetryhttps://digitalcommons.ursinus.edu/weekly/1726/thumbnail.jp

Search for Fractional Charges in Water

Results are presented from a search for fractional charges in water from a variety of natural sources. About 30 000 water drops have been measured, comprising 51 μg of water and dissolved materials. No evidence for fractional charge was seen

Bayesian inference on compact binary inspiral gravitational radiation signals in interferometric data

Presented is a description of a Markov chain Monte Carlo (MCMC) parameter estimation routine for use with interferometric gravitational radiational data in searches for binary neutron star inspiral signals. Five parameters associated with the inspiral can be estimated, and summary statistics are produced. Advanced MCMC methods were implemented, including importance resampling and prior distributions based on detection probability, in order to increase the efficiency of the code. An example is presented from an application using realistic, albeit fictitious, data.Comment: submitted to Classical and Quantum Gravity. 14 pages, 5 figure

Platelet-Associated Matrix Metalloproteinases Regulate Thrombus Formation and Exert Local Collagenolytic Activity

Objective Platelets are increasingly implicated in processes beyond hemostasis and thrombosis, such as vascular remodeling. Members of the matrix metalloproteinase (MMP) family not only remodel the extracellular matrix but also modulate platelet function. Here, we made a systematic comparison of the roles of MMP family members in acute thrombus formation under flow conditions and assessed platelet-dependent collagenolytic activity over time. Approach and Results Pharmacological inhibition of MMP-1 or MMP-2 (human) or deficiency in MMP-2 (mouse) suppressed collagen-dependent platelet activation and thrombus formation under flow, whereas MMP-9 inhibition/deficiency stimulated these processes. The absence of MMP-3 was without effect. Interestingly, MMP-14 inhibition led to the formation of larger thrombi, which occurred independently of its capacity to activate MMP-2. Platelet thrombi exerted local collagenolytic activity capable of cleaving immobilized dye-quenched collagen and fibrillar collagen fibers within hours, with loss of the majority of the platelet adhesive properties of collagen as a consequence. This collagenolytic activity was redundantly mediated by platelet-associated MMP-1, MMP-2, MMP-9, and MMP-14 but occurred independently of platelet -granule release (Nbeal2(-/-) mice). The latter was in line with subcellular localization experiments, which indicated a granular distribution of MMP-1 and MMP-2 in platelets, distinct from -granules. Whereas MMP-9 protein could not be detected inside platelets, activated platelets did bind plasma-derived MMP-9 to their plasma membrane. Overall, platelet MMP activity was predominantly membrane-associated and influenced by platelet activation status. Conclusions Platelet-associated MMP-1, MMP-2, MMP-9, and MMP-14 differentially modulate acute thrombus formation and at later time points limit thrombus formation by exerting collagenolytic activity

Rapid and sensitive detection of mycobacterium ulcerans by use of a loop-mediated isothermal amplification test

This work reports the design and evaluation of a rapid loop-mediated isothermal amplification test for detecting Mycobacterium ulcerans DNA based on the multicopy insertion sequence IS2404. The test is robust and specific with a detection limit equivalent to 20 copies of the target sequence (0.01 to 0.1 genome). The test has potential for the diagnosis of Buruli ulcer under field conditions

Search for Fractional Charges Produced in Heavy-Ion Collisions at 1.9 GeV/nucleon

An experiment was performed to capture fractionally charged particles produced in heavy-ion collisions and to concentrate them in samples suitable for analysis by various techniques. Two of the samples so produced have been searched, with use of an automated version of Millikan\u27s oil-drop apparatus. The beam was 56Fe at 1.9 GeV/nucleon, incident on a lead target. Less than one fractional charge per 1.0× 104 Fe-Pb collisions was found to be produced, and, with further assumptions, less than one per 2.0× 106 collisions