Lovie Joe

https://digitalcommons.library.umaine.edu/mmb-vp/4478/thumbnail.jp

Mapping Jewish Education: The National Picture

Based on interviews as well as a database of Jewish educational organizations, foundations, and programs, examines their accomplishments, challenges, future directions, and links within a Jewish educational system. Highlights the role of foundations

Production and Inventory Control in a Portland Cement Plant

Industrial Engineering and Managemen

Inoculation studies related to breeding for resistance to bacterial wilt in lespedeza

... cooperative investigation between the Department of Field Crops, Missouri Agricultural Experiment Station, University of Missouri, and Forage and Range Section, Field Crops Branch, Agricultural Research Service, U.S. Department of Agriculture...--P. [2].Digitized 2007 AES.Includes bibliographical references (page 47)

Rule-based Cross-matching of Very Large Catalogs

The NASA Extragalactic Database (NED) has deployed a new rule-based cross-matching algorithm called Match Expert (MatchEx), capable of cross-matching very large catalogs (VLCs) with >10 million objects. MatchEx goes beyond traditional position-based cross-matching algorithms by using other available data together with expert logic to determine which candidate match is the best. Furthermore, the local background density of sources is used to determine and minimize the false-positive match rate and to estimate match completeness. The logical outcome and statistical probability of each match decision is stored in the database and may be used to tune the algorithm and adjust match parameter thresholds. For our first production run, we cross-matched the GALEX All Sky Survey Catalog (GASC), containing nearly 40 million NUV-detected sources, against a directory of 180 million objects in NED. Candidate matches were identified for each GASC source within a 7''.5 radius. These candidates were filtered on position-based matching probability and on other criteria including object type and object name. We estimate a match completeness of 97.6% and a match accuracy of 99.75%. Over the next year, we will be cross-matching over 2 billion catalog sources to NED, including the Spitzer Source List, the 2MASS point-source catalog, AllWISE, and SDSS DR 10. We expect to add new capabilities to filter candidate matches based on photometry, redshifts, and refined object classifications. We will also extend MatchEx to handle more heterogenous datasets federated from smaller catalogs through NED's literature pipeline

HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs).

The tumor suppressor gene HIC1 (Hypermethylated In Cancer 1) encodes a transcriptional repressor mediating the p53-dependent apoptotic response to irreparable DNA double-strand breaks (DSBs) through direct transcriptional repression of SIRT1. HIC1 is also essential for DSB repair as silencing of endogenous HIC1 in BJ-hTERT fibroblasts significantly delays DNA repair in functional Comet assays. HIC1 SUMOylation favours its interaction with MTA1, a component of NuRD complexes. In contrast with irreparable DSBs induced by 16-hours of etoposide treatment, we show that repairable DSBs induced by 1 h etoposide treatment do not increase HIC1 SUMOylation or its interaction with MTA1. Furthermore, HIC1 SUMOylation is dispensable for DNA repair since the non-SUMOylatable E316A mutant is as efficient as wt HIC1 in Comet assays. Upon induction of irreparable DSBs, the ATM-mediated increase of HIC1 SUMOylation is independent of its effector kinase Chk2. Moreover, irreparable DSBs strongly increase both the interaction of HIC1 with MTA1 and MTA3 and their binding to the SIRT1 promoter. To characterize the molecular mechanisms sustained by this increased repression potential, we established global expression profiles of BJ-hTERT fibroblasts transfected with HIC1-siRNA or control siRNA and treated or not with etoposide. We identified 475 genes potentially repressed by HIC1 with cell death and cell cycle as the main cellular functions identified by pathway analysis. Among them, CXCL12, EPHA4, TGFβR3 and TRIB2, also known as MTA1 target-genes, were validated by qRT-PCR analyses. Thus, our data demonstrate that HIC1 SUMOylation is important for the transcriptional response to non-repairable DSBs but dispensable for DNA repair

Noorte spordiharrastuse struktuur ja arenguvõimalused

Käesolev uurimistöö, mis on teostatud TPÜ Spordisotsioloogia labori poolt Eesti sporditeabe sihtasutuse tellimusel käsitleb Eesti üldhariduskoolide 6. ja 9. klasside õpilaste liikumis- ja spordiharrastust koos seda mõjustavate tegurite kompleksi hinnangutega ning võimaldab võrdlust 1992/93 ja 1995/96 õppeaastal tehtud analoogsete uuringutega. Uurimuse eesmärgiks oli kooliõpilaste spordi-ja liikumisharrastuse kaardistamine ja muutumistendentside määratlemine, samuti sportimiskeskkonda kujundavate tegurite hindamine ja kehalise kasvatuse mõningate aspektide hindamine. Saadud informatsioon täpsustab olukorda (lisaks spordistatistikale) ning aitab põhjendada teid spordi-ja liikumisharrastuse laiendamiseks, mis loob omakorda eeldused spordimeisterlikkuse edendamiseks. Käesolev aruanne koos täiskasvanute spordiharrastuse uurimusega annab lisateavet vastavate spordikorralduslike meetmete leidmiseks ja rakendamiseks

MP755: Eastern Regional Potato Trials 2003: Summary of NE1014 Regional Project Field Testing of New Potato Clones

The objectives of this regional potato trial are (1) to develop pest-resistant, early-maturing, long-dormant potato varieties that will process from cold storage; (2) to evaluate new and specialty variet­ies developed in the Northeast; (3) to determine climatic effects on performance to develop pre­dictive models for potato improvement; and (4) determine heritability/linkage relationships and improve the genetic base of tetraploid cultivated varieties. The results presented in this report reflect a portion of the activity directed toward objectives 1, 2 and 3.https://digitalcommons.library.umaine.edu/aes_miscpubs/1020/thumbnail.jp