Characterizing Bars at z~0 in the optical and NIR: Implications for the Evolution of Barred Disks with Redshift

Critical insights on galaxy evolution stem from the study of bars. With the advent of HST surveys that trace bars in the rest-frame optical out to z~1, it is critical to provide a reference baseline for bars at z~0 in the optical band. We present results on bars at z~0 in the optical and NIR bands based on 180 spirals from OSUBSGS. (1) The deprojected bar fraction at z~0 is ~60% +/-6% in the NIR H-band and ~44% +/-6% in the optical B-band. (2) The results before and after deprojection are similar, which is encouraging for high-redshift studies that forego deprojection. (3) Studies of bars at z~0.2-1.0 (lookback time of 3-8 Gyr) have reported an optical bar fraction of ~30% +/-6%, after applying cutoffs in absolute magnitude (M_V = 1.5 kpc), and bar ellipticity (e_bar >= 0.4). Applying these exact cutoffs to the OSUBSGS data yields a comparable optical B-band bar fraction at z~0 of ~ 34%+/-6%. This rules out scenarios where the optical bar fraction in bright disks declines strongly with redshift. (4) Most (~70%) bars have moderate to high strentgh or ellipticity (0.50 <= e_bar <= 0.75). There is no bimodality in the distribution of e_bar. The H-band bar fraction and e_bar show no substantial variation across RC3 Hubble types Sa to Scd. (5) RC3 bar types should be used with caution. Many galaxies with RC3 types "AB" turn out to be unbarred and RC3 bar classes "B" and "AB" have a significant overlap in e_bar. (6) Most bars have sizes below 5 kpc. Bar and disk sizes correlate, and most bars have a_bar/R_25~0.1-0.5. This suggests that the growths of bars and disks are intimately tied.Comment: 11 pages, 17 figures, 3 tables, ApJ accepted, abridged abstract below. Minor changes and shortened paper for ApJ limits. For high resolution figures see http://www.as.utexas.edu/~marinova/paper1-highres.pd

Barred Galaxies in the Coma Cluster

We use ACS data from the HST Treasury survey of the Coma cluster (z~0.02) to study the properties of barred galaxies in the Coma core, the densest environment in the nearby Universe. This study provides a complementary data point for studies of barred galaxies as a function of redshift and environment. From ~470 cluster members brighter than M_I = -11 mag, we select a sample of 46 disk galaxies (S0--Im) based on visual classification. The sample is dominated by S0s for which we find an optical bar fraction of 47+/-11% through ellipse fitting and visual inspection. Among the bars in the core of the Coma cluster, we do not find any very large (a_bar > 2 kpc) bars. Comparison to other studies reveals that while the optical bar fraction for S0s shows only a modest variation across low-to-intermediate density environments (field to intermediate-density clusters), it can be higher by up to a factor of ~2 in the very high-density environment of the rich Coma cluster core.Comment: Proceedings of the Bash symposium, to appear in the Astronomical Society of the Pacific Conference Series, eds. L. Stanford, L. Hao, Y. Mao, J. Gree

Channel gain for a wrist-to-arm scenario in the 55-65 GHz frequency band

Wireless communication on the body is expected to become more important in the future. This communication will in certain scenarios benefit from higher frequencies of operation and their associated smaller antennas and potentially higher bandwidths. One of these scenarios is communication between a wristband and wearable sensors on the arm. In order to investigate the feasibility of such a scenario, propagation at 55â65 GHz along the arm is measured for two configurations. First, for increasing separation distances along the arm, and second for a transmitter is rotationally placed around the wrist. Two channel gain models are fitted to the data and used to obtain a channel gain exponent in the first configuration and loss per angle of rotation in the second configuration. These models are relevant inputs for the design of future wearable wireless systems

Respiratory Immunization With a Whole Cell Inactivated Vaccine Induces Functional Mucosal Immunoglobulins Against Tuberculosis in Mice and Non-human Primates

Vaccination through the natural route of infection represents an attractive immunization strategy in vaccinology. In the case of tuberculosis, vaccine delivery by the respiratory route has regained interest in recent years, showing efficacy in different animal models. In this context, respiratory vaccination triggers lung immunological mechanisms which are omitted when vaccines are administered by parenteral route. However, contribution of mucosal antibodies to vaccine- induced protection has been poorly studied. In the present study, we evaluated in mice and non-human primates (NHP) a novel whole cell inactivated vaccine (MTBVAC HK), by mucosal administration. MTBVAC HK given by intranasal route to BCG-primed mice substantially improved the protective efficacy conferred by subcutaneous BCG only. Interestingly, this improved protection was absent in mice lacking polymeric Ig receptor (pIgR), suggesting a crucial role of mucosal secretory immunoglobulins in protective immunity. Our study in NHP confirmed the ability of MTBVAC HK to trigger mucosal immunoglobulins. Importantly, in vitro assays demonstrated the functionality of these immunoglobulins to induce M. tuberculosis opsonization in the presence of human macrophages. Altogether, our results suggest that mucosal immunoglobulins can be induced by vaccination to improve protection against tuberculosis and therefore, they represent a promising target for next generation tuberculosis vaccines

Wnt4 and LAP2alpha as pacemakers of Thymic Epithelial Senescence

Age-associated thymic involution has considerable physiological impact by inhibiting de novo T-cell selection. This impaired T-cell production leads to weakened immune responses. Yet the molecular mechanisms of thymic stromal adipose involution are not clear. Age-related alterations also occur in the murine thymus providing an excellent model system. In the present work structural and molecular changes of the murine thymic stroma were investigated during aging. We show that thymic epithelial senescence correlates with significant destruction of epithelial network followed by adipose involution. We also show in purified thymic epithelial cells the age-related down-regulation of Wnt4 (and subsequently FoxN1), and the prominent increase in LAP2α expression. These senescence-related changes of gene expression are strikingly similar to those observed during mesenchymal to pre-adipocyte differentiation of fibroblast cells suggesting similar molecular background in epithelial cells. For molecular level proof-of-principle stable LAP2α and Wnt4-over-expressing thymic epithelial cell lines were established. LAP2α over-expression provoked a surge of PPARγ expression, a transcription factor expressed in pre-adipocytes. In contrast, additional Wnt4 decreased the mRNA level of ADRP, a target gene of PPARγ. Murine embryonic thymic lobes have also been transfected with LAP2α- or Wnt4-encoding lentiviral vectors. As expected LAP2α over-expression increased, while additional Wnt4 secretion suppressed PPARγ expression. Based on these pioneer experiments we propose that decreased Wnt activity and increased LAP2α expression provide the molecular basis during thymic senescence. We suggest that these molecular changes trigger thymic epithelial senescence accompanied by adipose involution. This process may either occur directly where epithelium can trans-differentiate into pre-adipocytes; or indirectly where first epithelial to mesenchymal transition (EMT) occurs followed by subsequent pre-adipocyte differentiation. The latter version fits better with literature data and is supported by the observed histological and molecular level changes

First Observation and Measurement of the Decay K+- -> pi+- e+ e- gamma

Using the full data set of the NA48/2 experiment, the decay K+- -> pi+- e+ e- gamma is observed for the first time, selecting 120 candidates with 7.3 +- 1.7 estimated background events. With K+- -> pi+- pi0D as normalisation channel, the branching ratio is determined in a model-independent way to be Br(K+- -> pi+- e+ e- gamma, m_eegamma > 260 MeV/c^2) = (1.19 +- 0.12_stat +- 0.04_syst) x 10^-8. This measured value and the spectrum of the e+ e- gamma invariant mass allow a comparison with predictions of Chiral Perturbation Theory.Comment: 13 pages, 3 figures. Accepted for publication in Phys.Lett.

Empirical parameterization of the K+- -> pi+- pi0 pi0 decay Dalitz plot

As first observed by the NA48/2 experiment at the CERN SPS, the \p0p0 invariant mass (M00) distribution from \kcnn decay shows a cusp-like anomaly at M00=2m+, where m+ is the charged pion mass. An analysis to extract the pi pi scattering lengths in the isospin I=0 and I=2 states, a0 and a2, respectively, has been recently reported. In the present work the Dalitz plot of this decay is fitted to a new empirical parameterization suitable for practical purposes, such as Monte Carlo simulations of K+- -> pi+- pi0 pi0 decays.Comment: 9 pages, 3 figures