Palliative large bowel resections. Impact of the laparoscopic approach

INTRODUCTION: Nowadays colorectal cancer (CRC) incidence rate increases in the Western world. The lack of effective screening programs results in diagnosis of advanced cases in our country. Combination of hematogenic, peritoneal or systemic CRC dissemination with present or potential complications from local disease is not an exception. The decision for palliative resection is not easy and is a matter of balance be­tween potential risks of operative intervention and advances due to local tumour resection. Positive aspects of the laparoscopic approach are important in planning of these interventions. The aim of this study is to as­sess the indications for laparoscopic palliative large bowel resections in the literature available and to share our own experience.PATIENTS AND METHODS: During a two-year period, in the HPB and General Surgery Clinic, Acibadem City Clinic, Tokuda Hospital of Sofia, six laparoscopic palliative colon resections were performed. In the all cases, multiple liver metastases were diagnosed without possibility of liver resection. The early periopera­tive results were analyzed.RESULTS: Four left colon resections were performed with primary anastomosis due to high-level large bow­el obstruction and two right colectomies were done for primary tumour bleeding. Three patients were over 77 years old and presented with comorbidity. Average hospital stay was 5,6 days. No perioperative compli­cations were observed.CONCLUSION: Minimal surgical trauma, short recovery period and well-defined indications are important features in the process of planning of palliative large bowel resections in patients with disseminated CRC. The objective is to reduce risks of complications connected with primary tumour and to assure a good pa­tient`s quality of life. Scr Sci Med 2017; 49(3): 27-3

RF surface resistance study of non-evaporable Getter coatings

In many particle accelerators the beam parameters could be affected by the beam pipe wakefield impedance. It is vital to understand how the wakefield impedance might vary due to various coatings on the surface of the vacuum chamber, and this can be derived from surface resistance measurements. The bulk conductivity of two types of NEG films (dense and columnar) is determined. This is achieved by measuring the surface resistance of NEG-coated samples using an RF test cavity and fitting the experimental data to a standard theoretical model. The conductivity values obtained are then used to compare resistive wall wakefield effects in beam pipes coated with either of the two types of film

Nonlinear waves and coherent structures in the quantum single-wave model

Starting from the von Neumann-Maxwell equations for the Wigner quasi-probability distribution and for the self-consistent electric field, the quantum analog of the classical single-wave model has been derived. The linear stability of the quantum single-wave model has been studied, and periodic in time patterns have been found both analytically and numerically. In addition, some features of quantum chaos have been detected in the unstable region in parameter space. Further, a class of standing-wave solutions of the quantum single-wave model has also been found, which have been observed to behave as stable solitary-wave structures. The analytical results have been finally compared to the exact system dynamics obtained by solving the corresponding equations in Schrodinger representation numerically.Comment: 10 pages, 9 figure

Nonlinear density waves in the single-wave model

The single-wave model equations are transformed to an exact hydrodynamic closure by using a class of solutions to the Vlasov equation corresponding to the waterbag model. The warm fluid dynamic equations are then manipulated by means of the renormalization group method. As a result, amplitude equations for the slowly varying wave amplitudes are derived. Since the characteristic equation for waves has in general three roots, two cases are examined. If all three roots of the characteristic equation are real, the amplitude equations for the eigenmodes represent a system of three coupled nonlinear equations. In the case, where the dispersion equation possesses one real and two complex conjugate roots, the amplitude equations take the form of two coupled equations with complex coefficients. The analytical results are then compared to the exact system dynamics obtained by solving the hydrodynamic equations numerically.Comment: 7 pages, To appear in the Physics of Plasmas, Volume 18, Issue

Crocus pallidus (Iridaceae)—A Neglected Species for the Bulgarian Flora and Critical Taxon in the Balkans

For a long time, the Balkan endemic species Crocus pallidus has been unconfirmed and neglected for the flora of Bulgaria. It has remained an uncertain species from the Balkans, often listed as a synonym of C. weldenii. The morphological resemblance to the albinistic forms of C. chrysanthus has led to incorrect identification in the past, resulting in uncertainty regarding the distribution of this species in Bulgaria. In this regard, a detailed morphological and anatomical study of Bulgarian natural populations was carried out. A phylogenetic comparison in the ITS region of two Bulgarian populations of C. pallidus with other related species was conducted, revealing the distinction of C. pallidus populations from the closely related C. weldenii. The recently described new endemic species from Turkey, C. thracicus, shows very similar morphological and anatomical characteristics to C. pallidus and logically continues the distribution range in Eastern Thrace, along the Black Sea coast. We have a basis for suggesting that it should be treated as a synonym of C. pallidus

Assessment of the acute impact of normobaric hypoxia as a part of an intermittent hypoxic training on heart rate variability

AbstractAimTo assess the dynamics of ANS by means of heart rate variability (HRV) during and after acute exposure to normobaric hypoxia, representing a single session of an intermittent hypoxic training protocol.Material and methodsTwenty four healthy males aged 28.0±7.2 (mean±SD) breathed hypoxic air (FIO2=12.3±1.5%) for one hour delivered via hypoxicator (AltiPro 8850 Summit+, Altitude Tech, Canada). Pulse oximetry and HRV were measured before, during and after the hypoxic exposure.ResultsAt the end of the hypoxic session all of the tested subjects had higher low frequency (lnLF) (6.9±1.1ms2 vs. 7.5±1.1ms2; p=0.042), LF/HF (1.5±0.8 vs. 3.3±2.8; p=0.007) and standard deviation 2 of the Poincaré plot (SD2) (92.8±140.0ms vs. 120.2±54.2ms; p=0.005) as well as increase in the Total power (7.7±1.1ms2 vs. 8.1±1.2ms2; p=0.032) and the Standard deviation of normal-to-normal interbeat intervals (SDNN) (57.3±31.0ms vs. 72.3±41.1ms; p=0.024) but lower Sample entropy (SampEn) (1.6±0.2 vs. 1.4±0.2; p=0.010). Immediately after the hypoxic exposure LF/HF lowered (3.3±2.8 vs. 2.2±1.8; p=0.001) but lnHF significantly increased (6.6±1.4ms2 vs. 7.1±1.3ms2; p=0.020).ConclusionAcute normobaric hypoxia as a part of a single session of an intermittent hypoxic training protocol leads to changes in the activity of the ANS. The sympathetic tone prevails during hypoxic exposure and parasympathetic tone increases immediately after the hypoxic factor is withdrawn

Design of the thermal and magnetic shielding for the LHC High Luminosity Crab-Cavity upgrade

Before the High Luminosity (Hi-Lumi) upgrade of the Large Hadron Collider (LHC), two pairs of superconducting compact Crab Cavities are to be tested within separate cryomodules, on the Super Proton Synchrotron (SPS) at CERN in 2018 prior to Long Shutdown 2. Two novel side-loaded cryomodules, which allow ease of access for assembly, inspection and maintenance, have been developed for the prototype tests. The cryomodule shielding includes a thermal shield and double layer magnetic shield, consisting of a warm-outer shield, and two cold-inner shields (one per cavity). Various constraints and considerations have led to unique cold shielding, mounted inside the cavity helium vessels, resulting in several design challenges. The shielding adopts and utilises the module’s side-loaded configuration, for continuity and accessibility, while satisfying tight spatial constraints and requirements to meet the functional specification. This paper outlines the design, analysis, manufacture and assembly of the Hi-Lumi SPS test cryomodule’s thermal and magnetic shielding, which are critical to achieving the operational stability