Effects of vitamin D supplementation on pulmonary function in postmenopausal women following an aquatic exercise program

Objective: This study sought to investigate the effects of vitamin D supplementation and aquatic exercise on pulmonary function in postmenopausal women. Materials and methods: This prospective and controlled study included 104 women (62 +/- 6.5 years) divided into three groups: a control group lacking vitamin D and calcium supplementation which remained sedentary (CGn = 17)a control group receiving vitamin D and calcium supplementation which remained sedentary (CDG, n = 33)and a group that completed aquatic exercises three times a week and received vitamin D and calcium supplementation (DTG, n = 54). Data before and after 6 months of the study were analyzed, including serum 25-hydroxyvitamin D (25(OH) D) and calcium concentrations, peak expiratory flow (PEF), forced vital capacity (FVC), and cirtometry. Results: We observed significant increases in 25(OH) D concentrations in CDG (52.9 +/- 2.4 to 69.1 +/- 2.2nmol/Lp < 0.0001) and DTG groups (55.5 +/- 3 to 71.5 +/- 3 nmol/Lp < 0.0001). PEF increased by 7 +/- 2% (p = 0.0080) in CDG group and 11 +/- 2% (p < 0.0001) in DTG group, whereas FVC increased by 7 +/- 2% (p = 0.0016) in the CDG group and 10 +/- 2% (p < 0.0001) in the DTG group, whereas CG had no changes in any of these parameters. The increment value of cirtometry in DTG group (+ 43 +/- 3%) were significantly (p < 0.0001) higher than those in CG (-4 +/- 8%) and CDG (+ 4 +/- 9%) groups. Conclusion: Our data suggest that vitamin D supplementation improves pulmonary function parameters in postmenopausal women.Fapesp (Fundacao de Amparo a Pesquisa do Estado de Sao Paulo)Federal AgencFederal Agency for Support and Evaluation of Graduate Education (Higher Education Personnel Improvement Coordination - Capes)Univ Fed Sao Paulo, Dept Med, Disciplina Endocrinol, Fac Med,Unifesp,EPM, Sao Paulo, SP, BrazilUniv Sao Judas Tadeu, Fisiol Translac, Programa Posgrad Educ Fis & Ciencias Envelhecimen, Sao Paulo, SP, BrazilUniv Sao Paulo, Escola Educ Fis & Esporte, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Med, Disciplina Endocrinol, Fac Med,Unifesp,EPM, Sao Paulo, SP, BrazilFAPESP: 08/50179-9Web of Scienc

Level of physical activity, aerobic power and perception of subjective memory loss in postmenopausal women

OBJECTIVE: To investigate the relationship between the level of physical activity and aerobic power with the subjective perception of memory loss in postmenopausal non-sedentary women. METHODS: The study included 131 women who engaged in physical activity twice a week. To evaluate the memory instruments the Memory Assessment Clinics Self-Ralph (MAC-Q) Questionnaire and the Prospective and Retrospective Memory Questionnaire (PRMQ) were used. The level of physical activity was identified by the International Physical Activity Questionnaire (IPAQ) and with the use of pedometers. The indicator of aerobic power was obtained by the 2-Minute Walking Test. To check the normality of the data we used the Kolmogorov-Smirnov test and performed the Spearman correlation (rho). We used the Kruskal-Wallis test to compare physical activity levels between groups. The level of significance was p&lt;0.05. RESULTS: The results show a better correlation of the subjective perception of memory loss with moderate and vigorous physical activities, but the correlations are weak and low. CONCLUSION: There was no significant association between total duration of walking per week, moderate and vigorous physical activity and subjective awareness of memory loss in postmenopausal women.</p

Lean mass as a determinant of bone mineral density of proximal femur in postmenopausal women

ABSTRACT Objective: To verify which component of body composition (BC) has greater influence on postmenopausal women bone mineral density (BMD). Subjects and methods: Four hundred and thirty women undergoing treatment for osteoporosis and 513 untreated women, except for calcium and vitamin D. Multiple linear regression analysis was performed in order to correlated BMD at lumbar spine (LS), total femur (FT), femoral neck (FN) with body mass (BM), total lean mass (LM) and total fat mass (FM), all determined by DXA. Results: BM significantly correlated with all bone sites in untreated and treated women (r = 0.420 vs 0.277 at LS; r = 0.490 vs 0.418 at FN, r = 0.496 vs 0.414 at FT, respectively). In untreated women, the LM correlated better than FM with all sites, explaining 179% of LS; 32.3% of FN and 30.2% of FT; whereas FM explained 13.2% of LS; 277% of FN, 23.4% of FT In treated women, correlations with BC were less relevant, with the LM explaining 6.7% of BMD at LS; 15.2% of FN, 16% of FT, whereas the FM explained 8.1% of LS; 179% of FN and 176% of FT. Conclusion: LM in untreated women was better predictor of BMD than FM, especialy for distal femur, where it explained more than 30% of the BMD, suggesting that maintaining a healthy muscle mass may contribute to decrease osteoporosis risk. Treatment with anti-osteoporotic drugs seems to mask these relationships. Arch Endocrinol Metab. 2018;62(4):431-