Оценка риска возникновения аварийных ситуаций на ЦОФ «Кузнецкая»

Оценивается риск возникновения аварийных ситуаций на предприятии, и разрабатываются мероприятия по их снижениюThe risk of accidents at the enterprise is assessed and measures are developed to reduce the

Determinants of health-related quality of life in school-aged children: A general population study in the Netherlands

Background: Health related quality of life is the functional effect of a medical condition and/or its therapy upon a patient, and as such is particularly suitable for describing the general health of children. The objective of this study was to identify and confirm potential determinants of health-related quality of life in children aged 4-11 years in the general population in the Netherlands. Understanding such determinants may provide insights into more targeted public health policy. Methods: As part of a population based cross sectional study, the Child Health Questionnaire (CHQ) Parental Form 28 was used to measure health-related quality of life in school-aged children in a general population sample. Parents of 10,651 children aged 4-11 years were interviewed from January 2001 to December 2009. Results: Multivariate and regression analyses demonstrated a declined CHQ Physical Summary score for children who had >1 conditions, disorders or acute health complaints and who were greater consumers of healthcare; children with a non-western immigrant background; and children whose parents did not work. Lower CHQ Psychosocial Summary score was reported for children who had >1 conditions, disorders or acute health complaints, boys, children of single parents and obese children. Conclusion: The best predictors of health-related quality of life are variables that describe use of health care and the number of disorders and health complaints. Nonetheless, a number of demographic, socio-economic and family/environmental determinants contribute to a child's health-related quality of life as well

Depression and body mass index, a u-shaped association

Background Results of studies concerning the association between obesity and depression are conflicting. Some find a positive association, some a negative association and some find no association at all. Most studies, however, examine a linear association between Body Mass Index (BMI) and depression. The present study investigates if a nonlinear (U-shaped) trend is preferable over a linear trend to describe the relationship between BMI and depression, which means that both underweight and obesity are associated with depression. Methods We investigated the existence of such a U-curve in a sample of 43,534 individuals, aged between 18–90 years, who participated in a cross-sectional study (Continuous Survey of Living Conditions) of physical and mental health in the general population of the Netherlands. We calculated linear and nonlinear (quadratic) ANOVA with polynomial contrast and curve fit regression statistics to investigate whether there was a U-shaped trend in the association between BMI and depression. Results We find a very significant U-shaped association between BMI categories (underweight, normal, overweight and obesity) and depression (p ≤ 0.001). There is a trend indicating a significant difference in the association between males and females (p = 0.05). We find a very significant U-shaped (quadratic) association between BMI (BMI2) and depression (p ≤ 0.001), continuous BMI is not linearly associated with depression (p = 0.514). Conclusion The results of this study give evidence for a significant U-shaped trend in the association between BMI and depression

Imaginaries of the Future City:Envisioning Climate Change and Technological Cityscapes through Dutch Contemporary Speculative Fiction

In this chapter, we address the flourishing and fast-growing production of future novels within contemporary Dutch literature since 2014. We analyse the ways in which Dutch authors use the technique of extrapolation to envision the urban/natural environment of the future, focused on a corpus of eight future novels from the period 2015–2021. First, we argue that, by indicating and comparing both spatial and temporal ‘reality markers’, speculation in contemporary Dutch literature tends to stay ‘close to home’. Second, we demonstrate that, overall, the themes of climate change and technologization are represented as highly intertwined in diverse constellations. In addition, we try to determine in what way the stories under investigation give both formally and thematically expression to a utopian impulse: Overall, do they show utopian elements or is the urban experience predominantly dystopian

Childhood chronic conditions and health-related quality of life: Findings from a large population-based study

The objective of this study was to assess the impact of health-related quality of life (HRQOL) across prevalent chronic conditions, individually and comorbid, in school-aged children in the Netherlands. 5301 children aged 4±11 years from the Dutch Health Interview Survey were included. Parents completed questionnaires regarding child and parental characteristics. HRQOL of children was measured using the Child Health Questionnaire Parent Form 28 (CHQ-PF28). Independent-t tests were used to assess differences in the mean scores of the CHQ-PF28 summary scales and profile scales between children with a prevalent chronic condition (excluding or including children with multiple chronic conditions) and children without a chronic condition. Cohen's effect sizes (d) were calculated to assess the clinical significance of difference. The mean age of children was 7.55 (SD 2.30) years; 50.0% were boys. In children without any chronic condition, the mean score of physical summary scale (PhS) was 58.53 (SD 4.28) and mean score of the psychosocial summary scale (PsS) was 53.86 (SD 5.87). Generally, PhS and/or PsS scores in children with only one condition were lower (p<0.05) than for children without chronic conditions. When children with multiple conditions were included, mean scores of CHQ-PF28 summary and profile scales were generally lower than when they were excluded. The present study shows important information regarding the impact of prevalent chronic conditions on HRQOL in a representative population-based sample of school-aged children in the Netherlands. The information could be used for developing a more holistic approach to patient care and a surveillance framework for health promotion

Two-month-old infants at risk for dyslexia do not discriminate vertical bar bAk vertical bar from vertical bar dAk vertical bar:A brain-mapping study

Dyslexics have problems with categorization of speech sounds, in particular when rapid temporal processing is involved such as in formant transitions of stop-consonants. Infants are already sensitive to such auditory features, but here we show that precursors of impaired categorization are already present in the brain responses of two-month-old infants at familial risk for dyslexia. Natural speech stimuli (/bAk/ and /dAk/), at either side of the phoneme boundary, induced multiple mismatch responses in control infants under pre-attentive and pre-cognitive conditions. Infants at-risk showed an attenuated early mismatch response and an absent late one, in addition to diminished cortical activity in the left hemisphere. These results are consistent with a temporal processing deficit in the infants at risk and may point to an early precursor of the disorder

Correction: Determinants of Health-Related Quality of Life in School-Aged Children: A General Population Study in the Netherlands.

[This corrects the article DOI: 10.1371/journal.pone.0125083.]

CHQ-PF28 scales, number of items per scale, and score interpretation.

<p>a. From the CHQ manual [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0125083#pone.0125083.ref002" target="_blank">2</a>]. Reproduced with permission from JM Landgraf.</p><p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0125083#t001fn001" target="_blank">^a</a></p