Avaliação do potencial antimicrobiano de compostos naturais obtidos de plantas da flora brasileira para tratamento e prevenção de cáries.

The main bacteria for the initial formation of dental plaque are of the genus Streptococcus and the Streptococcus mutans species is the main etiological agent of caries. The antimicrobial agent most commonly used to combat these conditions is chlorhexidine digluconate, but it has adverse effects that restrict its prolonged use. Thus, the search for alternative antimicrobial drugs with lower side effects is increasing. The aim of this work was to evaluate the antimicrobial potential of the benzophenones from Garcinia braziliensis Guttiferone-A, 7-epiclusianone, 2,2',4-trihydroxybenzophenone, and the diterpenoic acids copalic, 3-acetoxy-copalic and 3-hydroxycopalic, from Copaifera sp., as well as their associations against oral bacteria. The minimum inhibitory concentration of the compounds was determined by the microdilution broth in microplates, followed by the addition of resazurin and a simplified test of the interaction of the compounds by microdilution. As a result, the main antimicrobial compounds, against S. mutans, were copalic acid and 7- epiclusianone isolated (MICs between 62.5μg/mL and 30.45μg/mL, respectively) and in combination, where they had an additive effect, reducing their active concentrations in combination to 32.25μg/mL and 15.22μg/mL, respectively. Thus, it is concluded that the combination between copalic acid and 7-epiclusianone presents as promising for the construction of pharmaceutical formulations to combat dental plaque and caries.

Results from portable and of low cost equipment developed for detection of milk adulterations

Abstract This work presents the results of a device, MilkTech, developed to detect milk tampering, based on electrical measurements. The device indicates possible frauds by water, sodium chloride, caustic soda, ethyl alcohol and sodium bicarbonate. The advantages in relation to traditional methods are portability, low cost and detection of mixed frauds. The experiments were conducted in dairy plants at Governador Valadares, in Brazil. The results were compared with cryoscopy and chloride tests. It is demonstrated there is high correlation between MilkTech and Cryoscopy. For instance, the detection limit of the equipment for water addition with the set of analyzed data was 0.78% with precision of 1.1%. Adulterations with sodium chloride, caustic soda, ethyl alcohol and sodium bicarbonate are detected qualitatively, even when added with water, and MilkTech indicates “SUSPECT” milk

Results from portable and of low cost equipment developed for detection of milk adulterations

<div><p>Abstract This work presents the results of a device, MilkTech, developed to detect milk tampering, based on electrical measurements. The device indicates possible frauds by water, sodium chloride, caustic soda, ethyl alcohol and sodium bicarbonate. The advantages in relation to traditional methods are portability, low cost and detection of mixed frauds. The experiments were conducted in dairy plants at Governador Valadares, in Brazil. The results were compared with cryoscopy and chloride tests. It is demonstrated there is high correlation between MilkTech and Cryoscopy. For instance, the detection limit of the equipment for water addition with the set of analyzed data was 0.78% with precision of 1.1%. Adulterations with sodium chloride, caustic soda, ethyl alcohol and sodium bicarbonate are detected qualitatively, even when added with water, and MilkTech indicates “SUSPECT” milk.</p></div