Uniform Steiner bundles

In this work we study $k$-type uniform Steiner bundles, being $k$ the lowest degree of the splitting. We prove sharp upper and lower bounds for the rank in the case $k=1$ and moreover we give families of examples for every allowed possible rank and explain which relation exists between the families. After dealing with the case $k$ in general, we conjecture that every $k$-type uniform Steiner bundle is obtained through the proposed construction technique.Comment: 23 pages, to appear at Annales de l'Institut Fourie

Technological characterization of vaginal probiotic lactobacilli: resistance to osmotic stress and strains compatibility

Aims: The aim was to evaluate the osmotic stress resistance of vaginal beneficial probiotic strains, their growth kinetics and parameters when growing in salt-added culture media, and their compatibility to go further in the design of a probiotic formula for reconstitution of vaginal microbiome in women. Methods and Results: The resistance to osmotic stress of the lactobacilli was evaluated by determining their growth in MRS (as control) added with NaCl (2–8%). The most resistant strains were Lactobacillus gasseri CRL1509, L. rhamnosus CRL1332 and L. reuteri CRL1327 selected by statistical approaches and growth parameters. Electron microscopy was applied to determine changes. They maintain probiotic properties and viability. Some strains showed incompatibility, then they cannot be included in multistrain formulas. Conclusions: The resistance to different salt concentrations in vaginal lactobacilli is strain-specific, because the behaviour is different in strains identified into the same species. The resistance is not related to the metabolic groups. Significance and Impact of the Study: The resistance and survival to extreme osmotic resistance is one of the specific requirements of beneficial bacteria after the technological processes for their inclusion in probiotic formulas, in a way to express their beneficial characteristics and exert the effect on the host.Fil: Silva, Jessica Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Marchesi, Antonella. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Birgitt, Wiese. Hannover Medical School; AlemaniaFil: Nader, Maria Elena Fatima. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentin

Uniform Steiner bundles

In this work we study $k$-type uniform Steiner bundles, being $k$ the lowest degree of the splitting. We prove sharp upper and lower bounds for the rank in the case $k=1$ and moreover we give families of examples for every allowed possible rank and explain which relation exists between the families. After dealing with the case $k$ in general, we conjecture that every $k$-type uniform Steiner bundle is obtained through the proposed construction technique

Relacion entre algunas obras en prosa de Valle-Inclan y algunas de D\u27Annunzio

Varios críticos han notado la influencia de Gabriele D’Annunzio en la obra de Don Ramón del Valle-Inclán y uno, Julio Casares, ha señalado un episodio de clara imitación, pero, por lo que pudimos averiguar, no se ha hecho un estudio detenido puntualizando las muchas semejanzas específicas que existen entre los dos autores. En este trabajo se examinarán varios recursos estilísticos y temas que aparecen en algunas obras en prosa de la fase modernista de Valle-Inclán, relacionándolos con los que fueron empleados anteriormente por Gabriele D’Annunzio en sus obras en prosa. Esto pondrá en evidencia las semejanzas específicas que se hallan en los varios escritos, y comprobará que Valle-Inclán verdaderamente siguió las huellas dannunzianas. En este estudio se tomarán en cuenta únicamente los rasgos más significativos para mostrar puntos comunes entre los dos autores. Nos remitimos a los escritos de D’Annunzio solamente en lo que puede tener relación con los escritos de Valle-Inclán considerados aquí

Campylobacter jejuni fatal sepsis in a patient with non-Hodgkin’s lymphoma: Case report and literature review of a difficult diagnosis

Campylobacter jejuni (C. jejuni) bacteremia is difficult to diagnose in individuals with hematological disorders undergoing chemotherapy. The cause can be attributed to the rarity of this infection, to the variable clinical presentation, and to the partial overlapping symptoms underlying the disease. Here, we report a case of a fatal sepsis caused by C. jejuni in a 76-year-old Caucasian man with non-Hodgkin's lymphoma. After chemotherapeutic treatment, the patient experienced fever associated with severe neutropenia and thrombocytopenia without hemodynamic instability, abdominal pain, and diarrhea. The slow growth of C. jejuni in the blood culture systems and the difficulty in identifying it with conventional biochemical phenotyping methods contributed to the delay of administering a targeted antimicrobial treatment, leading to a fatal outcome. Early recognition and timely intervention are critical for the successful management of C. jejuni infection. Symptoms may be difficult to recognize in immunocompromised patients undergoing chemotherapy. Thus, it is important to increase physician awareness regarding the clinical manifestations of C. jejuni to improve therapeutic efficacy. Moreover, the use of more aggressive empirical antimicrobial treatments with aminoglycosides and/or carbapenems should be considered in immunosuppressed patients, in comparison to those currently indicated in the guidelines for cancer-related infections supporting the use of cephalosporins as monotherapy

Irreducibility of the moduli space of orthogonal instanton bundles on Pn

In order to obtain existence criteria for orthogonal instanton bundles on $\mathbb{P}^n$, we provide a bijection between equivalence classes of orthogonal instanton bundles with no global sections and symmetric forms. Using such correspondence we are able to provide explicit examples of orthogonal instanton bundles with no global sections on $\mathbb{P}^n$ and prove that every orthogonal instanton bundle with no global sections on $\mathbb{P}^n$ and charge $c \geq 2$ has rank $r \leq(n-1) c$. We also prove that when the rank $r$ of the bundles reaches the upper bound, $\mathcal{M}_{\mathbb{P}}^{\mathcal{O}}(c, r)$, the coarse moduli space of orthogonal instanton bundles with no global sections on $\mathbb{P}^n$, with charge $c \geq 2$ and rank $r$, is affine, smooth, reduced and irreducible. Last, we construct Kronecker modules to determine the splitting type of the bundles in $\mathcal{M}_{\mathbb{P} n}^{\mathcal{O}}(c, r)$, whenever is non-empty

Anti-Candida activity of beneficial vaginal lactobacilli in in vitro assays and in a murine experimental model

Vulvovaginal candidiasis (VVC) is one of the most frequent infections affecting women worldwide. Healthy vaginalmicrobiota is dominated by lactobacilli, which form a strong defense line against pathogens. In this work, in vitroantimicrobial properties of thirty vaginal Lactobacillus strains were evaluated against eleven Candida vaginal clinical isolates,employing three different methods. Also, the effect of intravaginal (i.va.) administrations (preventive, therapeutic andpreventive-therapeutic) of L. reuteri CRL1324 or L. rhamnosus CRL1332 strains against the i.va. challenge with Candida albicansC2 (C.a.) was evaluated in a murine experimental model. From the results of agar overlay and liquid medium assays theselected lactobacilli strains have shown to inhibit the growth of at least one Candida strain. The inhibition was mainly dueto the effect of organic acids. Anti-Candida activity was not evidenced in the agar plate diffusion method. In theexperimental murine model, only preventive-therapeutic administration of both lactobacilli was able to significantly reduceviable C.a. numbers recovered in vaginal washes and the leukocyte influx induced by the fungi. In conclusion, lactobacilliexhibited in vitro and in vivo antimicrobial effects on Candida, suggesting that they could be promising candidates forprotection against VVC. Lactobacilli predominant in human vagina and protect from VVC. The manuscript reports different methods to determine lactobacilli inhibitory effect at the laboratory, and protection against Candida in murine vagina.Fil: de Gregorio, Priscilla Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Silva, Jessica Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Marchesi, Antonella. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; ArgentinaFil: Nader, Maria Elena Fatima. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Centro de Referencia para Lactobacilos; Argentin