Non-Unitary and Unitary Transitions in Generalized Quantum Mechanics, New Small Parameter and Information Problem Solving

Quantum Mechanics of the Early Universe is considered as deformation of a well-known Quantum Mechanics. Similar to previous works of the author, the principal approach is based on deformation of the density matrix with concurrent development of the wave function deformation in the respective Schr{\"o}dinger picture, the associated deformation parameter being interpreted as a new small parameter. It is demonstrated that the existence of black holes in the suggested approach in the end twice causes nonunitary transitions resulting in the unitarity. In parallel this problem is considered in other terms: entropy density, Heisenberg algebra deformation terms, respective deformations of Statistical Mechanics, - all showing the identity of the basic results. From this an explicit solution for Hawking's informaion paradox has been derived.Comment: 18 page

Residence time statistics for NN blinking quantum dots and other stochastic processes

We present a study of residence time statistics for $N$ blinking quantum dots. With numerical simulations and exact calculations we show sharp transitions for a critical number of dots. In contrast to expectation the fluctuations in the limit of $N \to \infty$ are non-trivial. Besides quantum dots our work describes residence time statistics in several other many particle systems for example $N$ Brownian particles. Our work provides a natural framework to detect non-ergodic kinetics from measurements of many blinking chromophores, without the need to reach the single molecule limit

The Universe as a Nonuniform Lattice in the Finite-Dimensional Hypercube II.Simple Cases of Symmetry Breakdown and Restoration

This paper continues a study of field theories specified for the nonuniform lattice in the finite-dimensional hypercube with the use of the earlier described deformation parameters. The paper is devoted to spontaneous breakdown and restoration of symmetry in simple quantum-field theories with scalar fields. It is demonstrated that an appropriate deformation opens up new possibilities for symmetry breakdown and restoration. To illustrate, at low energies it offers high-accuracy reproducibility of the same results as with a nondeformed theory. In case of transition from low to higher energies and vice versa it gives description for new types of symmetry breakdown and restoration depending on the rate of the deformation parameter variation in time, and indicates the critical points of the previously described lattice associated with a symmetry restoration. Besides, such a deformation enables one to find important constraints on the initial model parameters having an explicit physical meaning.Comment: 9 pages,Revte

Pure States, Mixed States and Hawking Problem in Generalized Quantum Mechanics

This paper is the continuation of a study into the information paradox problem started by the author in his earlier works. As previously, the key instrument is a deformed density matrix in quantum mechanics of the early universe. It is assumed that the latter represents quantum mechanics with fundamental length. It is demonstrated that the obtained results agree well with the canonical viewpoint that in the processes involving black holes pure states go to the mixed ones in the assumption that all measurements are performed by the observer in a well-known quantum mechanics. Also it is shown that high entropy for Planck remnants of black holes appearing in the assumption of the Generalized Uncertainty Relations may be explained within the scope of the density matrix entropy introduced by the author previously. It is noted that the suggested paradigm is consistent with the Holographic Principle. Because of this, a conjecture is made about the possibility for obtaining the Generalized Uncertainty Relations from the covariant entropy bound at high energies in the same way as R. Bousso has derived Heisenberg uncertainty principle for the flat space.Comment: 12 pages,no figures,some corrections,new reference

Predicting carcinogenicity by using batteries of dependent short-term tests.

Among the various methods for predicting carcinogenicity from a battery of short-term tests (STTs), the carcinogenicity prediction and battery selection (CPBS) procedure is the most prominent. A major assumption of CPBS is that the STTs used in the prediction are conditionally independent. Results of recent National Toxicology Program studies of four commonly used in vitro STTs contradict this assumption, thereby necessitating modification of CPBS to accommodate dependencies. This is accomplished via log-linear modeling, which then also yields an important dividend: standard errors for the predicted probabilities of carcinogenicity

Quantum Mechanics at Planck's scale and Density Matrix

In this paper Quantum Mechanics with Fundamental Length is chosen as Quantum Mechanics at Planck's scale. This is possible due to the presence in the theory of General Uncertainty Relations. Here Quantum Mechanics with Fundamental Length is obtained as a deformation of Quantum Mechanics. The distinguishing feature of the proposed approach in comparison with previous ones, lies on the fact that here density matrix subjects to deformation whereas so far commutators have been deformed. The density matrix obtained by deformation of quantum-mechanical density one is named throughout this paper density pro-matrix. Within our approach two main features of Quantum Mechanics are conserved: the probabilistic interpretation of the theory and the well-known measuring procedure corresponding to that interpretation. The proposed approach allows to describe dynamics. In particular, the explicit form of deformed Liouville's equation and the deformed Shr\"odinger's picture are given. Some implications of obtained results are discussed. In particular, the problem of singularity, the hypothesis of cosmic censorship, a possible improvement of the definition of statistical entropy and the problem of information loss in black holes are considered. It is shown that obtained results allow to deduce in a simple and natural way the Bekenstein-Hawking's formula for black hole entropy in semiclassical approximation.Comment: 18 pages,Latex,new reference

Improved plasmids for gene targeting at the his-3 locus of Neurospora crassa by electroporation: Correction

Two mistakes in our article on gene replacement by gene targeting at the his-3 locus (Margolin, B.S. et al., 1997, FGN 44:34-36) have come to our attention

Improved plasmids for gene targeting at the his-3 locus of Neurospora crassa by electroporation

We report two new plasmids, pBM60 and pBM61, and procedures to efficiently generate single- copy transformants targeted to the his-3 locus in Neurospora crassa

Superaging correlation function and ergodicity breaking for Brownian motion in logarithmic potentials

We consider an overdamped Brownian particle moving in a confining asymptotically logarithmic potential, which supports a normalized Boltzmann equilibrium density. We derive analytical expressions for the two-time correlation function and the fluctuations of the time-averaged position of the particle for large but finite times. We characterize the occurrence of aging and nonergodic behavior as a function of the depth of the potential, and support our predictions with extensive Langevin simulations. While the Boltzmann measure is used to obtain stationary correlation functions, we show how the non-normalizable infinite covariant density is related to the super-aging behavior.Comment: 16 pages, 6 figure