The Left-To-Die Boat: Review 2

In March 2011 an inflatable boat carrying 72 asylum seekers from sub-Saharan Africa set out from the coast of Libya hoping to reach the Italian island of Lampedusa. As one Italian official commented, sailing from Libya towards Italy should have been ‘a bit like doing a slalom between military ships’. Yet as, out of fuel, supplies of food and water dwindled to nothing and the people on board began to get sick and die, the boat continued to drift and no help came. Eventually it floated all the way back to the Libyan coast. Of the 50 men, 20 women and two babies who set out to sea, only eleven remained alive. Sharon Davis and Geoff Parish reconstruct this tragedy through interviews with five young men who survived the trip. Their first-person accounts of the journey are augmented by interviews with sympathetic Dutch politician Tineke, Rome-based Eritrean Priest Father Mussie Zerai, who was contacted by the passengers by satellite phobe, human rights investigator Lorenzo Pezzani, who forensically reconstructed the boat’s movements, and dour NATO spokesperson Oana Lungescu. One survivor (Abu Kurke) speaks in halting English; for the others the vernacular is faded under voice-overs. It is raw, simple narrative, expertly selected and edited to move the story seamlessly forward while also allowing listeners time to form mental images of the boat and its passengers and to absorb the emotional impact of what they are hearing. The survivors’ individual accounts overlap and repeat to poetic effect, underscoring the veracity of their testimony. The survivors’ tale floats on a bed of sound – the splash of waves; the hum of a boat motor; restrained, ominous music (with cello predominating), and the occasionally distant chime from an old clock tower marking the relentless passing of time and its deadly impact on the voyage. The radio makers’ approach is dignified, restrained and powerful. Just as the clean lines of minimalist architecture can rely on sophisticated engineering, so the apparent simplicity of a chronological account conceals the artistry, deep thought and sheer hard work of radio production. A strong undercurrent of anger flows through the documentary, and we are given strong encouragement to doubt that NATO has been fully truthful in its response to the tragedy. The Left-To-Die Boat won a United Nations Association of Australia Media Peace Prize and was shortlisted for a Sony Academy award (UK), the New South Wales Premier\u27s Literary Awards and the Australian Human Rights Awards

Mapping the Galactic Halo with blue horizontal branch stars from the 2dF quasar redshift survey

We use 666 blue horizontal branch (BHB) stars from the 2Qz redshift survey to map the Galactic halo in four dimensions (position, distance and velocity). We find that the halo extends to at least 100 kpc in Galactocentric distance, and obeys a single power-law density profile of index ~-2.5 in two different directions separated by 150 degrees on the sky. This suggests that the halo is spherical. Our map shows no large kinematically coherent structures (streams, clouds or plumes) and appears homogeneous. However, we find that at least 20% of the stars in the halo reside in substructures and that these substructures are dynamically young. The velocity dispersion profile of the halo appears to increase towards large radii while the stellar velocity distribution is non Gaussian beyond 60 kpc. We argue that the outer halo consists of a multitude of low luminosity overlapping tidal streams from recently accreted objects.Comment: Accepted for publication in the Astrophysical Journal Requires emulateapj to proces

Long-term safety and efficacy of teriflunomide : nine-year follow-up of the randomized TEMSO study

This study was funded by Sanofi Genzyme.OBJECTIVE: To report safety and efficacy outcomes from up to 9 years of treatment with teriflunomide in an extension (NCT00803049) of the pivotal phase 3 Teriflunomide Multiple Sclerosis Oral (TEMSO) trial (NCT00134563). METHODS: A total of 742 patients entered the extension. Teriflunomide-treated patients continued the original dose; those previously receiving placebo were randomized 1:1 to teriflunomide 14 mg or 7 mg. RESULTS: By June 2013, median (maximum) teriflunomide exposure exceeded 190 (325) weeks per patient; 468 patients (63%) remained on treatment. Teriflunomide was well-tolerated with continued exposure. The most common adverse events (AEs) matched those in the core study. In extension year 1, first AEs of transient liver enzyme increases or reversible hair thinning were generally attributable to patients switching from placebo to teriflunomide. Approximately 11% of patients discontinued treatment owing to AEs. Twenty percent of patients experienced serious AEs. There were 3 deaths unrelated to teriflunomide. Soon after the extension started, annualized relapse rates and gadolinium-enhancing T1 lesion counts fell in patients switching from placebo to teriflunomide, remaining low thereafter. Disability remained stable in all treatment groups (median Expanded Disability Status Scale score ≤2.5; probability of 12-week disability progression ≤0.48). CONCLUSIONS: In the TEMSO extension, safety observations were consistent with the core trial, with no new or unexpected AEs in patients receiving teriflunomide for up to 9 years. Disease activity decreased in patients switching from placebo and remained low in patients continuing on teriflunomide. CLASSIFICATION OF EVIDENCE: This study provides Class III evidence that long-term treatment with teriflunomide is well-tolerated and efficacy of teriflunomide is maintained long-term.Publisher PDFPeer reviewe

Handel - Macht - Kapital: Historische Dimensionen wirtschaftlichen Handelns

Erschienen als Band 13 in der Reihe "Historica et Didactica: Fortbildung Geschichte. Ideen und Materialien für Unterricht und Lehre", herausgegeben von Noyan Dinçkal, Reinhild Kreis, Bärbel Kuhn, Matthias Weipert, Astrid Windus.Handel, Macht und Kapital – diese drei Begriffe stehen im Mittelpunkt des Bandes, der sich mit den historischen Dimensionen wirtschaftlichen Denkens und Handelns beschäftigt. Durch die Auseinandersetzung mit ökonomischen Praktiken und Diskursen aus verschiedenen Zeiten soll ein Bewusstsein für die Zusammenhänge von Wirtschaften und anderen Aspekten der Lebenswelt geschaffen werden. Dieser Zugang zur Wirtschaftsgeschichte ermöglicht es, gegenwärtige Wirtschaftsweisen in ihrer Historizität zu erfassen und zu erkennen, dass diese nicht das Produkt einer naturgesetzlichen Entwicklung sind. Ziel ist es, über einen kulturgeschichtlichen Zugang zur Wirtschaftsgeschichte an aktuelle Debatten über Globalisierung und Kapitalismus anzuknüpfen. Schülerinnen und Schüler werden durch die Auseinandersetzung mit historischen Text- und Bildquellen motiviert, sich eigene, differenzierte Urteile über verschiedene Wirtschaftsformen und ihre Auswirkungen auf Mensch und Umwelt zu bilden. Bestehende Inhalte des Lehrplans können dabei in neuer Weise erschlossen werden – sei es an außerschulischen Lernorten, über thematische Längsschnitte, im fächerübergreifenden Unterricht oder in Unterrichtsprojekten

Comparative in situ analyses of cell wall matrix polysaccharide dynamics in developing rice and wheat grain

Cell wall polysaccharides of wheat and rice endosperm are an important source of dietary fibre. Monoclonal antibodies specific to cell wall polysaccharides were used to determine polysaccharide dynamics during the development of both wheat and rice grain. Wheat and rice grain present near synchronous developmental processes and significantly different endosperm cell wall compositions, allowing the localisation of these polysaccharides to be related to developmental changes. Arabinoxylan (AX) and mixed-linkage glucan (MLG) have analogous cellular locations in both species, with deposition of AX and MLG coinciding with the start of grain filling. A glucuronoxylan (GUX) epitope was detected in rice, but not wheat endosperm cell walls. Callose has been reported to be associated with the formation of cell wall outgrowths during endosperm cellularisation and xyloglucan is here shown to be a component of these anticlinal extensions, occurring transiently in both species. Pectic homogalacturonan (HG) was abundant in cell walls of maternal tissues of wheat and rice grain, but only detected in endosperm cell walls of rice in an unesterified HG form. A rhamnogalacturonan-I (RG-I) backbone epitope was observed to be temporally regulated in both species, detected in endosperm cell walls from 12 DAA in rice and 20 DAA in wheat grain. Detection of the LM5 galactan epitope showed a clear distinction between wheat and rice, being detected at the earliest stages of development in rice endosperm cell walls, but not detected in wheat endosperm cell walls, only in maternal tissues. In contrast, the LM6 arabinan epitope was detected in both species around 8 DAA and was transient in wheat grain, but persisted in rice until maturity

Crop Updates 2006 - Cereals

This session covers twenty nine papers from different authors: PLENARY 1. The 2005 wheat streak mosaic virus epidemic in New South Wales and the threat posed to the Western Australian wheat industry, Roger Jones and Nichole Burges, Department of Agriculture SOUTH COAST AGRONOMY 2. South coast wheat variety trial results and best options for 2006, Mohammad Amjad, Ben Curtis and Wal Anderson, Department of Agriculture 3. Dual purpose winter wheats to improve productivity, Mohammad Amjad and Ben Curtis, Department of Agriculture 4. South coast large-scale premium wheat variety trials, Mohammad Amjad and Ben Curtis, Department of Agriculture 5. Optimal input packages for noodle wheat in Dalwallinu – Liebe practice for profit trial, Darren Chitty, Agritech Crop Research and Brianna Peake, Liebe Group 6. In-crop risk management using yield prophet®, Harm van Rees1, Cherie Reilly1, James Hunt1, Dean Holzworth2, Zvi Hochman2; 1Birchip Cropping Group, Victoria; 2CSIRO, Toowoomba, Qld 7. Yield Prophet® 2005 – On-line yield forecasting, James Hunt1, Harm van Rees1, Zvi Hochman2,Allan Peake2, Neal Dalgliesh2, Dean Holzworth2, Stephen van Rees1, Trudy McCann1 and Peter Carberry2; 1Birchip Cropping Group, Victoria; 2CSIRO, Toowoomba, Qld 8. Performance of oaten hay varieties in Western Australian environments, Raj Malik and Kellie Winfield, Department of Agriculture 9. Performance of dwarf potential milling varieties in Western Australian environments, Kellie Winfield and Raj Malik, Department of Agriculture 10. Agronomic responses of new wheat varieties in the Southern agricultural region of WA, Brenda Shackley and Judith Devenish, Department of Agriculture 11. Responses of new wheat varieties to management factors in the central agricultural region of Western Australia, Darshan Sharma, Steve Penny and Wal Anderson,Department of Agriculture 12. Sowing time on wheat yield, quality and $ - Northern agricultural region, Christine Zaicou-Kunesch, Department of Agriculture NUTRITION 13.The most effective method of applying phosphorus, copper and zinc to no-till crops, Mike Bolland and Ross Brennan, Department of Agriculture 14. Uptake of K from the soil profile by wheat, Paul Damon and Zed Rengel, Faculty of Natural and Agricultural Sciences, University of Western Australia 15. Reducing nitrogen fertiliser risks, Jeremy Lemon, Department of Agriculture 16. Yield Prophet® and canopy management, Harm van Rees1, Zvi Hochman2, Perry Poulton2, Nick Poole3, Brooke Thompson4, James Hunt1; 1Birchip Cropping Group, Victoria; 2CSIRO, Toowoomba, Qld; 3Foundation for Arable Research, New Zealand; 4Cropfacts, Victoria 17. Producing profits with phosphorus, Stephen Loss, CSBP Ltd, WA 18. Potassium response in cereal cropping within the medium rainfall central wheatbelt, Jeff Russell1, Angie Roe2 and James Eyres2, Department of Agriculture1, Farm Focus Consultants, Northam2 19. Matching nitrogen supply to wheat demand in the high rainfall cropping zone, Narelle Simpson, Ron McTaggart, Wal Anderson, Lionel Martin and Dave Allen, Department of Agriculture DISEASES 20. Comparative study of commercial wheat cultivars and differential lines (with known Pm resistance genes) to powdery mildew response, Hossein Golzar, Manisha Shankar and Robert Loughman, Department of Agriculture 21. On farm research to investigate fungicide applications to minimise leaf disease impacts in wheat – part II, Jeff Russell1, Angie Roe2and James Eyres2, Department of Agriculture1, and Farm Focus Consultants, Northam2 22. Disease resistance update for wheat varieties in WA, Manisha Shankar, John Majewski, Donna Foster, Hossein Golzar, Jamie Piotrowski, Nicole Harry and Rob Loughman, Department of Agriculture 23. Effect of time of stripe rust inoculum arrival on variety response in wheat, Manisha Shankar, John Majewski and Rob Loughman, Department of Agriculture 24. Fungicide seed dressing management of loose smut in Baudin barley, Geoff Thomas and Kith Jayasena, Department of Agriculture PESTS 25. How to avoid insect contamination in cereal grain at harvest, Svetlana Micic, Paul Matson and Tony Dore, Department of Agriculture ABIOTIC 26. Environment – is it as important as variety in sprouting tolerance? Thomas (Ben) Biddulph1, Dr Daryl Mares1, Dr Julie Plummer1 and Dr Tim Setter2, School of Plant Biology, University of Western Australia1 and Department of Agriculture2 27. Frost or fiction, Garren Knell, Steve Curtin and Wade Longmuir, ConsultAg Pty Ltd, WA 28. High moisture wheat harvesting in Esperance 2005, Nigel Metz, South East Premium Wheat Growers Association (SEPWA) Projects Coordinator, Esperance, WA SOILS 28. Hardpan penetration ability of wheat roots, Tina Botwright Acuña and Len Wade, School of Plant Biology, University of Western Australia MARKETS 29. Crop shaping to meet predicted market demands for wheat in the 21st Century, Cindy Mills and Peter Stone,Australian Wheat Board, Melbourn