The CorDis Corpus Mark-up and Related Issues

CorDis is a large, XML, TEI-conformant, POS-tagged, multimodal, multigenre corpus representing a significant portion of the political and media discourse on the 2003 Iraqi conflict. It was generated from different sub-corpora which had been assembled by various research groups, ranging from official transcripts of Parliamentary sessions, both in the US and the UK, to the transcripts of the Hutton Inquiry, from American and British newspaper coverage of the conflict to White House press briefings and to transcriptions of American and British TV news programmes. The heterogeneity of the data, the specificity of the genres and the diverse discourse analytical purposes of different groups had led to a wide range of coding strategies being employed to make textual and meta-textual information retrievable. The main purpose of this paper is to show the process of harmonisation and integration whereby a loose collection of texts has become a stable architecture. The TEI proved a valid instrument to achieve standardisation of mark-up. The guidelines provide for a hierarchical organisation which gives the corpus a sound structure favouring replicability and enhancing the reliability of research. In discussing some examples of the problems encountered in the annotation, we will deal with issues like consistency and re-usability, and will examine the constraints imposed on data handling by specific research objectives. Examples include the choice to code the same speakers in different ways depending on the various (institutional) roles they may assume throughout the corpus, the distinction between quotations of spoken or written discourse and quotations read aloud in the course of a spoken text, and the segmentation of portions of news according to participants interaction and use of camera/voiceover

Operative and nonoperative management for renal trauma. Comparison of outcomes. A systematic review and meta-analysis

INTRODUCTION: Preservation of kidney and renal function is the goal of nonoperative management (NOM) of renal trauma (RT). The advantages of NOM for minor blunt RT have already been clearly described, but its value for major blunt and penetrating RT is still under debate. We present a systematic review and meta-analysis on NOM for RT, which was compared with the operative management (OM) with respect to mortality, morbidity, and length of hospital stay (LOS). METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-analyses statement was followed for this study. A systematic search was performed on Embase, Medline, Cochrane, and PubMed for studies published up to December 2015, without language restrictions, which compared NOM versus OM for renal injuries. RESULTS: Twenty nonrandomized retrospective cohort studies comprising 13,824 patients with blunt (2,998) or penetrating (10,826) RT were identified. When all RT were considered (American Association for the Surgery of Trauma grades 1-5), NOM was associated with lower mortality and morbidity rates compared to OM (8.3% vs 17.1%, odds ratio [OR] 0.471; 95% confidence interval [CI] 0.404-0.548; P<0.001 and 2% vs 53.3%, OR 0.0484; 95% CI 0.0279-0.0839, P<0.001). Likewise, NOM represented the gold standard treatment resulting in a lower mortality rate compared to OM even when only high-grade RT was considered (9.1% vs 17.9%, OR 0.332; 95% CI 0.155-0.708; P=0.004), be they blunt (4.1% vs 8.1%, OR 0.275; 95% CI 0.0957-0.788; P=0.016) or penetrating (9.1% vs 18.1%, OR 0.468; 95% CI 0.398-0.0552; P<0.001). CONCLUSION: Our meta-analysis demonstrated that NOM for RT is the treatment of choice not only for AAST grades 1 and 2, but also for higher grade blunt and penetrating RT

Homogeneously alloyed CdSe1-xSx QDs (0 ≤ x ≤ 1) : an efficient synthesis for full optical tunability

In the field of fluorescent semiconductor quantum dots (QDs), alloyed QDs open up new possibilities and opportunities. Indeed, these systems allow to tune the optical properties of the nanocrystals without changing their size. This is of particular interest for the integration of the QDs in devices such as LEDs or for their use as biological labels. We recently developed a novel method for the synthesis of CdSe and ZnSe binary QDs in colloidal solutions that is fast and highly efficient. This method is based on a heterogeneous Se-ODE precursor consisting of a simple dispersion of Se powder (200 mesh) in octadecene (ODE) and showing very high reactivity towards Cd precursor. In this contribution we will demonstrate that this method can be extended to the synthesis of CdSe1-xSx homogeneously alloyed QDs (0 ≤ x ≤ 1)

Differences between computed tomoghaphy and surgical findings in acute complicated diverticulitis

Summary Background/Objective: A preoperative reliable classification system between clinical and computed tomography (CT) findings to better plan surgery in acute complicated diverticulitis (ACD) is lacking. We studied the inter-observer agreement of CT scan data and their concordance with the preoperative clinical findings and the adherence with the intraoperative status using a new classification of diverticular disease (CDD). Methods: 152 patients operated on for acute complicated diverticulitis (ACD) were retrospectively enrolled. All patients were studied with CT scan within 24 h before surgery and CT images were blinded reanalyzed by 2 couples of radiologists (A/B). Kappa value evaluated the inter-observer agreement between radiologists and the concordance between CDD, preoperative clinical findings and findings at operation. Univariate and multivariate analysis were used to evaluate the predicting values of CT classification and CDD stage at surgery on postoperative outcomes. Results: Overall inter-observer agreement for the CDD was high, with a kappa value of 0.905 (95% CI Z 0.850e0.960) for observers A and B, while the concordance between radiologica

Hollow viscus injuries. Predictors of outcome and role of diagnostic delay

INTRODUCTION: Hollow viscus injuries (HVIs) are uncommon but potentially catastrophic conditions with high mortality and morbidity rates. The aim of this study was to analyze our 16-year experience with patients undergoing surgery for blunt or penetrating bowel trauma to identify prognostic factors with particular attention to the influence of diagnostic delay on outcome. METHODS: From our multicenter trauma registry, we selected 169 consecutive patients with an HVI, enrolled from 2000 to 2016. Preoperative, intraoperative, and postoperative data were analyzed to assess determinants of mortality, morbidity, and length of stay by univariate and multivariate analysis models. RESULTS: Overall mortality and morbidity rates were 15.9% and 36.1%, respectively. The mean length of hospital stay was 23±7 days. Morbidity was independently related to an increase of white blood cells (P=0.01), and to delay of treatment >6 hours (P=0.033), while Injury Severity Score (ISS) (P=0.01), presence of shock (P=0.01), and a low diastolic arterial pressure registered at emergency room admission (P=0.02) significantly affected postoperative mortality. CONCLUSION: There is evidence that patients with clinical signs of shock, low diastolic pressure at admission, and high ISS are at increased risk of postoperative mortality. Leukocytosis and delayed treatment (>6 hours) were independent predictors of postoperative morbidity. More effort should be made to increase the preoperative detection rate of HVI and reduce the delay of treatment

Investigating the Incidence of Value Added Tax on Households Income: New Evidence from Italy

This paper analyses the incidence of the Value Added Tax (VAT) on Italian households income. To address this question, we developed a non-behavioural microsimulation model, the Value Added Tax Simulation Model (VATSIM-DF II). The goals of VATSIM-DF (II) are to estimate actual and expected VAT revenues, assess the VAT incidence on households disposable income, and simulate the distributional effects of changes in fiscal policies in Italy. Compared to existing models, the main achievements of this study are: (i) the creation of a unique original dataset, which includes tax register data; (ii) the implementation of a matching procedure, based on Tax Register data, which outperforms other data fusion strategies used in the existing literature. These innovations allow us to create a reliable and unique dataset to simulate changes in VAT and to produce results consistent with the most updated macroeconomic data. We tested our model, at current VAT legislation, and we show the VAT burden on Italian households confirming the regressivity of VAT. Finally, we analyse the effect of a revenue neutral reform, with two VAT rates, which applies the reduced VAT rate also to female and babies sanitary products

Vox2Vox: 3D-GAN for Brain Tumour Segmentation

Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histological sub-regions, i.e., peritumoral edema, necrotic core, enhancing and non-enhancing tumour core. Although brain tumours can easily be detected using multi-modal MRI, accurate tumor segmentation is a challenging task. Hence, using the data provided by the BraTS Challenge 2020, we propose a 3D volume-to-volume Generative Adversarial Network for segmentation of brain tumours. The model, called Vox2Vox, generates realistic segmentation outputs from multi-channel 3D MR images, segmenting the whole, core and enhancing tumor with mean values of 87.20%, 81.14%, and 78.67% as dice scores and 6.44mm, 24.36mm, and 18.95mm for Hausdorff distance 95 percentile for the BraTS testing set after ensembling 10 Vox2Vox models obtained with a 10-fold cross-validation