6,005 research outputs found
A dynamical systems approach to the discrimination of the modes of operation of cryptographic systems
Evidence of signatures associated with cryptographic modes of operation is
established. Motivated by some analogies between cryptographic and dynamical
systems, in particular with chaos theory, we propose an algorithm based on
Lyapunov exponents of discrete dynamical systems to estimate the divergence
among ciphertexts as the encryption algorithm is applied iteratively. The
results allow to distinguish among six modes of operation, namely ECB, CBC,
OFB, CFB, CTR and PCBC using DES, IDEA, TEA and XTEA block ciphers of 64 bits,
as well as AES, RC6, Twofish, Seed, Serpent and Camellia block ciphers of 128
bits. Furthermore, the proposed methodology enables a classification of modes
of operation of cryptographic systems according to their strength.Comment: 14 pages, 10 figure
Towards the Thermodynamics of Localization Processes
We study the entropy time evolution of a quantum mechanical model, which is
frequently used as a prototype for Anderson's localization. Recently Latora and
Baranger [V. Latora, M. Baranger, Phys. Rev.Lett. 82, 520(1999)] found that
there exist three entropy regimes, a transient regime of passage from dynamics
to thermodynamics, a linear in time regime of entropy increase, namely a
thermodynamic regime of Kolmogorov kind, and a saturation regime. We use the
non-extensive entropic indicator recently advocated by Tsallis [ C. Tsallis, J.
Stat. Phys. 52, 479 (1988)] with a mobile entropic index q, and we find that
with the adoption of the ``magic'' value q = Q = 1/2 the Kolmogorov regime
becomes more extended and more distinct than with the traditional entropic
index q = 1. We adopt a two-site model to explain these properties by means of
an analytical treatment and we argue that Q =1/2 might be a typical signature
of the occurrence of Anderson's localization.Comment: 13 pages, 8 figures submitted to Phys. Rev.
TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy
Significance
Alzheimer’s disease (AD) is the most common cause of dementia and is a major public health problem for which there is currently no disease-modifying treatment. There is an urgent need for greater understanding of the molecular mechanisms underlying neurodegeneration in patients to create better therapeutic options. Recently, genetic studies uncovered novel AD risk variants in the microglial receptor, triggering receptor expressed on myeloid cells 2 (TREM2). Previous studies suggested that loss of TREM2 function worsens amyloid-β (Aβ) plaque-related toxicity. In contrast, we observe TREM2 deficiency mitigates neuroinflammation and protects against brain atrophy in the context of tau pathology. These findings indicate dual roles for TREM2 and microglia in the context of amyloid versus tau pathology, which are important to consider for potential treatments targeting TREM2.</jats:p
Signature of Electronic Correlations in the Optical Conductivity of the Doped Semiconductor Si:P
Electronic transport in highly doped but still insulating silicon at low
temperatures is dominated by hopping between localized states; it serves as a
model system of a disordered solid for which the electronic interaction can be
investigated. We have studied the frequency-dependent conductivity of
phosphorus-doped silicon in the THz frequency range (30 GHz to 3 THz) at low
temperatures K. The crossover in the optical conductivity from a
linear to a quadratic frequency dependence as predicted by Efros and Shklovskii
is observed qualitatively; however, the simple model does not lead to a
quantitative agreement. Covering a large range of donor concentration, our
temperature- and frequency-dependent investigations reveal that electronic
correlation effects between the localized states play an important and complex
role at low temperatures. In particular we find a super-linear frequency
dependence of the conductivity that highlights the influence of the density of
states, i.e. the Coulomb gap, on the optical conductivity. When approaching the
metal-to-insulator transition by increasing doping concentration, the
dielectric constant and the localization length exhibit critical behavior.Comment: 9 pages, 8 figures, 1 tabl
Análisis de susceptibilidad a deslizamientos empleando el proceso de jerarquía analítica en una carretera Amazónica del Ecuador
The Puyo-Tena roadway is prone to landslides due to the geodynamics, geomorphology, and geological materials of the area (unstable outcrops and strata). In recent years, this problem has persistently caused the road to be partially or completely disabled on numerous occasions. The objective of the research was to generate a cartographic model of landslides susceptibility based on variables such as slope, geological formations, land cover and land use, as well as distances to faults, road, and rivers. The degree of landslides incidence was estimated as the linear combination of the weighted variables using the analytic hierarchy process. The importance of this semi quantitative method lies in its ability to break down a complex decision problem into a simpler and more coherent decision model. The resulting cartographic model was classified into five susceptibility categories: very low, low, moderate, high, and very high. The results showed that 17 km out of the 80 km of the Puyo-Tena roadway have a high probability of landslides, which is equivalent to 21.25% of the road. Furthermore, within this percentage, it was determined that there are fifteen regions with a high probability of landslides due to their location in areas with steep slopes, porous and permeable lithology, a large number of rivers, and agricultural soils. The area under the curve (AUC) of the receiver operating characteristic (ROC) was used for model verification. The verification results showed that the cartographic model for the study area has an accuracy value of 83.7%. The cartographic model of landslide susceptibility will enable relevant decisions to be made to mitigate potential hazards that may endanger transporters, material goods, and residents of the area. La carretera Puyo-Tena es propensa a deslizamientos de tierra debido a la geodinámica, geomorfología y materiales geológicos de la zona (afloramientos y estratos inestables). En los últimos años, este problema ha provocado de forma persistente la inutilización parcial o total de la carretera en numerosas ocasiones. El objetivo de la investigación fue generar un modelo cartográfico de susceptibilidad a deslizamientos a partir de variables como la pendiente, las formaciones geológicas, la cobertura y uso de la tierra, así como las distancias a fallas, carretera y ríos. El grado de incidencia de deslizamientos se estimó como la combinación lineal de las variables ponderadas mediante el proceso de jerarquía analítica. La importancia de este método semicuantitativo radica en su capacidad para desagregar un problema de decisión complejo en un modelo de decisión más simple y coherente. El modelo cartográfico resultante se reclasificó en cinco categorías de susceptibilidad: muy baja, baja, moderada, alta y muy alta. Los resultados mostraron que 17 km de los 80 km de la carretera Puyo-Tena tienen una alta probabilidad a deslizamientos, lo que equivale a 21,25% de la carretera. Además, dentro de este porcentaje, se determinó que existen quince regiones con alta probabilidad de deslizamientos debido a su ubicación en zonas con fuertes pendientes, litología porosa y permeable, gran cantidad de ríos y suelos agrícolas. Para la verificación del modelo se utilizó el área bajo la curva (en inglés AUC) de la característica operativa del receptor (en inglés ROC). Los resultados de la verificación mostraron que el modelo cartográfico para el áre de estudio tiene un valor de precisión de 83,7%. El modelo cartográfico de susceptibilidad a deslizamientos permitirá tomar las decisiones pertinentes para mitigar eventos potenciales que puedan poner en peligro a transportistas, bienes materiales y residentes de la zona.
A covariant formalism for Chern-Simons gravity
Chern--Simons type Lagrangians in dimensions are analyzed from the
point of view of their covariance and globality. We use the transgression
formula to find out a new fully covariant and global Lagrangian for
Chern--Simons gravity: the price for establishing globality is hidden in a
bimetric (or biconnection) structure. Such a formulation allows to calculate
from a global and simpler viewpoint the energy-momentum complex and the
superpotential both for Yang--Mills and gravitational examples.Comment: 12 pages,LaTeX, to appear in Journal of Physics
Hawking Radiation as Tunneling for Extremal and Rotating Black Holes
The issue concerning semi-classical methods recently developed in deriving
the conditions for Hawking radiation as tunneling, is revisited and applied
also to rotating black hole solutions as well as to the extremal cases. It is
noticed how the tunneling method fixes the temperature of extremal black hole
to be zero, unlike the Euclidean regularity method that allows an arbitrary
compactification period. A comparison with other approaches is presented.Comment: 17 pages, Latex document, typos corrected, four more references,
improved discussion in section
Neoplasms and novel gammaherpesviruses in critically endangered captive European minks (Mustela lutreola)
13 Päg.
Centro de Investigación en Sanidad Animal (CISA)The European mink (Mustela lutreola) is a riparian mustelid, considered one of the most endangered carnivores in the world. Alpha, beta and gammaherpesviruses described in mustelids have been occasionally associated with different pathological processes. However, there is no information about the herpesviruses species infecting European minks. In this study, 141 samples of swabs (oral, conjunctival, anal), faeces and tissues from 23 animals were analysed for herpesvirus (HV) using a pan-HV-PCR assay. Two different, potentially novel, gammaherpesvirus species were identified in 12 samples from four animals (17.3%), and tentatively named Mustelid gammaherpesvirus-2 (MUGHV-2) and MuGHV-3. Gross examination was performed on dead minks (n = 11), while histopathology was performed using available samples from HV-positive individuals (n = 2), identifying several neoplasms, including B-cell lymphoma (identified by immunohistochemistry) with intralesional syncytia and intranuclear inclusion bodies characteristic of HV (n = 1), pulmonary adenocarcinoma (n = 1), and biliary (n = 1) and preputial (n = 1) cystadenomas, as well as other lesions (e.g., axonal vacuolar degeneration [n = 2] and neuritis [n = 1]). Viral particles, consistent with HVs, were observed by electron microscopy in the mink with neural lymphoma and inclusion bodies. This is the first description of neoplasms and concurrent gammaherpesvirus infection in European minks. The pathological, ultrastructural and PCR findings (MuGHV-2) in the European mink with lymphoma strongly suggest a potential role for this novel gammaherpesvirus in its pathogenesis, as it has been reported in other HV-infected species with lymphoma. The occurrence of neural lymphoma with intralesional syncytia and herpesviral inclusions is, however, unique among mammals. Further research is warranted to elucidate the potential oncogenic properties of gammaherpesviruses in European mink and their epidemiology in the wild population.Innovation Initiative Grant (IIG) of the Edinburgh Fund (University of Edinburgh); Norwegian University of Life Sciences; Generalitat de Catalunya; São Paulo Research Foundation, Grant/Award Number: 2018/20956-08 and 2018/25069-7; University of EdinburghPeer reviewe
Superradiance Transition in Photosynthetic Light-Harvesting Complexes
We investigate the role of long-lasting quantum coherence in the efficiency
of energy transport at room temperature in Fenna-Matthews-Olson photosynthetic
complexes. The excitation energy transfer due to the coupling of the light
harvesting complex to the reaction center ("sink") is analyzed using an
effective non-Hermitian Hamiltonian. We show that, as the coupling to the
reaction center is varied, maximal efficiency in energy transport is achieved
in the vicinity of the superradiance transition, characterized by a segregation
of the imaginary parts of the eigenvalues of the effective non-Hermitian
Hamiltonian. Our results demonstrate that the presence of the sink (which
provides a quasi--continuum in the energy spectrum) is the dominant effect in
the energy transfer which takes place even in absence of a thermal bath. This
approach allows one to study the effects of finite temperature and the effects
of any coupling scheme to the reaction center. Moreover, taking into account a
realistic electric dipole interaction, we show that the optimal distance from
the reaction center to the Fenna-Matthews-Olson system occurs at the
superradiance transition, and we show that this is consistent with available
experimental data.Comment: 9 page
Path integrals approach to resisitivity anomalies in anharmonic systems
Different classes of physical systems with sizeable electron-phonon coupling
and lattice distortions present anomalous resistivity behaviors versus
temperature. We study a molecular lattice Hamiltonian in which polaronic charge
carriers interact with non linear potentials provided by local atomic
fluctuations between two equilibrium sites. We study a molecular lattice
Hamiltonian in which polaronic charge carriers interact with non linear
potentials provided by local atomic fluctuations between two equilibrium sites.
A path integral model is developed to select the class of atomic oscillations
which mainly contributes to the partition function and the electrical
resistivity is computed in a number of representative cases. We argue that the
common origin of the observed resistivity anomalies lies in the time retarded
nature of the polaronic interactions in the local structural instabilities.Comment: 4 figures, to appear in Phys.Rev.B, May 1st (2001
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