Interruptions Produced by the Mollucan Students in the Fellowship Meeting

This thesis is about a study of the interruptions produced by the Moluccan students in a fellowship meeting, consisting of fifteen students as the respondents, who are divided into two: the chairperson and the members. The purposes of the study are to know the tokens and the functions of interruptions used by the chairperson and the members of the meeting by considering social role as the social factor. The writer applies the theory of interruptions by Tannen (1990) and Wardhaugh (1985) as the main theories. Besides, the writer also uses the theory of social role by Johnstone (2008) and the theory of discourse markers by Schiffrin (2003) as the supporting theories. The writer used qualitative approach to conduct this research. The writer discovered that the chairperson produced more tokens (19) than the members (13). Moreover, the writer found that the respondents produced Ambonese tokens, such as “Hiii”, “Weee”, “Seng”, “Eee”, and Suroboyoan tokens, such as “Lho” and “Itulho”. Both the chairperson and the members produced “other” functions the most with 58.75% and 63.81%. In conclusion, social role influenced the interruptions and their functions, and the number of tokens produced by the participants

Optical studies of the ultraluminous X-ray source NGC1313 X-2

NGC1313 X-2 was among the first ultraluminous X-ray sources discovered, and has been a frequent target of X-ray and optical observations. Using the HST/ACS multi-band observations, this source is identified with a unique counterpart within an error circle of 0\farcs2. The counterpart is a blue star on the edge of a young cluster of $\le10^7$ years amid a dominant old stellar population. Its spectral energy distribution is consistent with that for a Z=0.004 star with 8.5 $M_\odot$ about $5\times10^6$ years old, or for an O7 V star at solar metallicity. The counterpart exhibited significant variability of $\Delta m = 0.153\pm0.033$ mag between two F555W observations separated by three months, reminiscent of the ellipsoidal variability due to the orbital motion of this ULX binary.Comment: 21 pages, 7 figures, scheduled for the ApJ June 10, 2007, v662n 1 issu

The Value of a Longitudinal Human Immunodeficiency Virus Track for Medical Students: 10-Year Program Evaluation

We surveyed graduates of a longitudinal medical school human immunodeficiency virus curriculum to evaluate its impact. Respondents felt comfortable caring for people with human immunodeficiency virus (PWH) and found value from the curriculum regardless of ultimate career path. Programs like this contribute to the development of culturally sensitive clinicians comfortable caring for PWH

The multifactorial pathways towards resistance to the cytosine analogues emtricitabine and lamivudine: Evidences from literature

The article by Bulteel et al.,1 published in the September issue of the journal, has investigated the rate of M184V emergence in patients receiving HAART combinations containing efavirenz (EFV), tenofovir (TDF) and lamivudine (3 TC) or emtricitabine (FTC) within the UK Collaborative HIV Cohort. By analyzing 304 genotypic resistance tests, the authors asserted that, although patients receiving 3 TC-based regimens were more likely to develop M184V than those receiving FTC-based regimens (event rate: 0.55 [95%CI: 0.28–0.96] for 3 TC versus 0.34 [95%CI: 0.21–0.46] for FTC), this association was not statistically significant in both univariable and multivariable models. These results are different from those reported in previous studies from our and other groups2, 3 and 4 showing a significant decrease in M184V emergence in patients failing FTC + TDF-based compared to 3 TC + TDF-based HAART (Table 1). The lower prevalence of M184V in FTC-containing regimen was also supported by a recently published letter showing a strong trend (P = 0.051) towards higher rates of resistance to the 3 TC containing regimen 5.5 (1.8–12.8) per 1000 patient years when compared with the FTC containing regimens 1.7 (0.8–3.2) per 1000 patient year

Modeling the radial abundance distribution of the transition galaxy ngc 1313

NGC 1313 is the most massive disk galaxy showing a flat radial abundance distribution in its interstellar gas, a behavior generally observed in magellanic and irregular galaxies. We have attempted to reproduce this flat abundance distribution using a multiphase chemical evolution model, which has been previously used sucessfully to depict other spiral galaxies along the Hubble morphological sequence. We found that it is not possible to reproduce the flat radial abundance distribution in NGC 1313, and at the same time, be consistent with observed radial distributions of other key parameters such the surface gas density and star formation profiles. We conclude that a more complicated galactic evolution model including radial flows, and possibly mass loss due to supernova explosions and winds, is necessary to explain the apparent chemical uniformity of the disk of NGC 1313Comment: 14 paginas, 4 figures, to be published in ApJ, apri

Efficacy of once daily darunavir/ritonavir 800/100 mg in PI/r-experienced HIV-1 infected patients with suppressed HIV-1 replication: the RADAR study

International audiencen.

Dielectric Properties of Materials Showing Constant-Phase-Element (CPE) Impedance Response

Constant-Phase Elements (CPE) are often used to fit impedance data arising from a broad range of experimental systems. Four approaches were used to interpret CPE parameters associated with the impedance response of human skin and two metal oxides in terms of characteristic frequencies and film thickness. The values obtained with each approach were compared against independent measurements. The power-law model developed recently by Hirschorn et al.1,2 provided the most reliable interpretation for systems with a normal distribution of properties. Readers are cautioned that the CPE parameter Q does not provide an accurate value for capacitance, even when the CPE exponent α is greater than 0.9

Prevalence of resistance mutations related to integrase inhibitor S/GSK1349572 in HIV-1 subtype B raltegravir-naive and -treated patients

Objectives To compare the frequency of previously in vitro-selected integrase mutations (T124A, T124A/S153F, S153Y, T124A/S153Y and L101I/T124A/S153Y) conferring resistance to S/GSK1349572 between HIV-1 subtype B integrase inhibitor (INI)-naive and raltegravir-treated patients. Methods Integrase sequences from 650 INI-naive patients and 84 raltegravir-treated patients were analysed. Results The T124A mutation alone and the combination T124A/L101I were more frequent in raltegravir-failing patients than in INI-naive patients (39.3% versus 24.5%, respectively, P = 0.005 for T124A and 20.2% versus 10.0%, respectively, P = 0.008 for T124A/L101I). The S153Y/F mutations were not detected in any integrase sequence (except for S153F alone, only detected in one INI-naive patient). Conclusions T124A and T124A/L101I, more frequent in raltegravir-treated patients, could have some effect on raltegravir response and their presence could play a role in the selection of other mutations conferring S/GSK1349572 resistance. The impact of raltegravir-mediated changes such as these on the virological response to S/GSK1349572 should be studied further