Study the influence of rose hip extract on the functional and technological properties of a fermented dairy products

The need to develop new types of functional products is due to the increased demand of the population for the products of this group. The subject of the study was a fermented milk drink with rosehip extract. The article suggests the possibility of using an extract of plant origin - rosehip in the production of fermented milk drink in order to give it restorative, preventive properties. The technology of extraction of rosehip fruits growing in the territory of Zhambyl region is proposed, organoleptic, physico-chemical and microbiological quality indicators of finished syrups are presented, confirming the expediency of using the extract in the technology of obtaining enriched fermented milk products. On the basis of scientific experiments, the optimal dosages of the applied extract, recipes for a readymade fermented milk drink using rosehip extract were determined. The nutritional value was calculated and the storage capacity of the fermented milk drink was determined - 7 days at a temperature of (4±2)°C. Industrial approbation of a ready-made functional fermented milk drink with rosehip fruit extract was carried out at «Galenika» LLP, Taraz, Zhambyl region. The approbation confirmed the possibility of introducing the developed formulation, technology of fermented milk drink with rosehip extract in industrial production conditions. The quality indicators of the finished product meet the requirements of GOST

Inflammatory Serum Biomarkers in Colorectal Cancer in Kazakhstan Population

Colorectal cancer is a type of oncopathology widespread in Kazakhstan. The genetic component, as well as the possible etiopathogenetic mechanisms, is widely studied. One of the most promising areas is the study of diagnostic and prognostic possibilities of inflammatory biomarkers in patients with different degrees of tumor differentiation. The following biomarkers were included in the study panel: stem cell factor (SCF), vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF2), interleukin 6 (IL6), interleukin 8 (IL8), macrophage migration inhibitory factor (MIF), soluble Fas (SFAS), soluble Fas ligand (sFASL), transforming growth factor β (TGF), tumor necrosis factor (TNF), TNF-related apoptosis-inducing ligand (TRAIL), and programmed death ligand 1 (PD-L1). The data of our study show that most of the basic proinflammatory cytokines are involved in the systemic process and their levels do not depend on the level of tissue differentiation. Serum PD-L1 has shown itself to be a promising marker for tumor growth, which depends on the degree of differentiation

The globalizability of temporal discounting

Economic inequality is associated with preferences for smaller, immediate gains over larger, delayed ones. Such temporal discounting may feed into rising global inequality, yet it is unclear whether it is a function of choice preferences or norms, or rather the absence of sufficient resources for immediate needs. It is also not clear whether these reflect true differences in choice patterns between income groups. We tested temporal discounting and five intertemporal choice anomalies using local currencies and value standards in 61 countries (N = 13,629). Across a diverse sample, we found consistent, robust rates of choice anomalies. Lower-income groups were not significantly different, but economic inequality and broader financial circumstances were clearly correlated with population choice patterns