178 research outputs found

    A sort of homecoming : incarceration and the housing security of urban men

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    While individuals returning from prison face many barriers to successful re-entry, among the most serious are the challenges they face in securing housing. Housing has long been recognized as a prerequisite for stable employment, access to social services, and other aspects of individual and family functioning. The formerly incarcerated face several administrative and de facto restrictions on their housing options; however, little is known about the unique instabilities that they face. We use a longitudinal survey of urban families to examine housing insecurity among nearly 3,000 urban men, including over 1,000 with incarceration histories. We find that men recently incarcerated face greater housing insecurity, including both serious hardships such as homelessness, and precursors to homelessness such as residential turnover and relying on others for housing expenses. Their increased risk is tied both to diminished annual earnings and other factors, including, potentially, evictions from public housing supported by Federal "one-strike" policies

    Influence of low doses of gamma irradiation on cowpea beetle Callosobruchus maculatus (F.) (Coleoptera: Chrysomelidae): Poster

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    Phytosanitary irradiation for food commodities has been widely accepted in recent years. Gamma irradiation has been used as a phytosanitary treatment against microbial diseases, insect infestation and food spoilage. The goal of the current study was to determine the lowest possible dose of gamma irradiation that will induce longterm sterility of insects through generations. The effect of four gamma irradiation doses examined were; 20,40, 50 and 70 Gy. Irradiated males were crossed with normal females. For the cowpea beetle Callosobruchus maculatus(F.), adult fecundity, hatchability, adult emergence, sterility% was investigated. 100% adult mortality was achieved by 70 Gy dose. Fecundity, hatchability, number of adults emerged, sterility% were significantly reduced when males exposed to 20, 40, and 50 Gy compared to the control. The effect of parental irradiated males exposed to 20 Gy on F2 generation was also studied. Fecundity, hatchability, number of adult emerged, sterility% were significantly reduced in F2 compared to F1 and control progeny. Interestingly, for F1 generation, the effect of gamma rays on adult emergence% exhibit a hermetic effect response although it was not significant. These results demonstrat that pulse irradiation relying on low-doses of gamma radiation induce inherited semi-sterility through generations and is a very promising phytosanitary food technology for postharvest treatments.Phytosanitary irradiation for food commodities has been widely accepted in recent years. Gamma irradiation has been used as a phytosanitary treatment against microbial diseases, insect infestation and food spoilage. The goal of the current study was to determine the lowest possible dose of gamma irradiation that will induce longterm sterility of insects through generations. The effect of four gamma irradiation doses examined were; 20,40, 50 and 70 Gy. Irradiated males were crossed with normal females. For the cowpea beetle Callosobruchus maculatus(F.), adult fecundity, hatchability, adult emergence, sterility% was investigated. 100% adult mortality was achieved by 70 Gy dose. Fecundity, hatchability, number of adults emerged, sterility% were significantly reduced when males exposed to 20, 40, and 50 Gy compared to the control. The effect of parental irradiated males exposed to 20 Gy on F2 generation was also studied. Fecundity, hatchability, number of adult emerged, sterility% were significantly reduced in F2 compared to F1 and control progeny. Interestingly, for F1 generation, the effect of gamma rays on adult emergence% exhibit a hermetic effect response although it was not significant. These results demonstrat that pulse irradiation relying on low-doses of gamma radiation induce inherited semi-sterility through generations and is a very promising phytosanitary food technology for postharvest treatments

    Application de la technique de 137Cs Ă  l'estimation de l'Ă©rosion hydrique dans le bassin versant de Moulay Bouchta, Rif occidental, Maroc

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    Au Maroc, l’érosion hydrique est un processus majeur de dégradation des sols, en particulier dans la zone rifaine, où l’érosion engendre des dégâts importants en amont et en aval des structures hydrauliques, remettant en cause la durabilité de l’exploitation de ces dernières. De même, l’évaluation quantitative de ce processus reste difficile à mettre en oeuvre du fait de la complexité du comportement des particules du sol, aussi bien dans l’espace que dans le temps, en réponse à la diversité et l’interaction des facteurs naturels et anthropiques. C’est ainsi qu’on propose d’évaluer les sédiments déplacés qui sont l’élément perceptible de ce phénomène à travers le suivi du traceur radioactif le Césium 137 (137Cs) caractérisé par son affinité aux particules fines du sol (argile et matière organique). La méthodologie adoptée combine l’utilisation de la technique du 137Cs et les Systèmes d’Information Géographique (SIG), ainsi, on a défini une trentaine d’unités fonctionnelles combinant trois paramètres agro-environnementaux « l’occupation du sol, le type de sol et l’inclinaison de la pente ». Jusqu’à présent, on a échantillonné 9 unités, représentant 68% du bassin versant, deux sites de référence et un prélèvement au niveau de la retenue du barrage pour évaluer le taux de sédimentation. Ensuite, les échantillons ont été analysés par spectrométrie gamma, les activités du 137Cs (Bq/kg), ainsi obtenues, sont converties en taux de perte ou de gain du sol (t/ha/an) à l’aide du modèle masse balance 2 (MBM2) pour les sites perturbés (terrains cultivés) et le modèle de diffusion et migration (DMM) pour les sites non perturbés (forêts et matorrals). Les résultats des pertes en sol à long terme (~ 50 ans) montrent que la majorité des sédiments arrachés (98%) proviennent des terrains cultivés. Ces terrains présentent des taux d’érosion variant de 18 à 36 (t/ha/an), alors que les sites du matorral et de la forêt présentent des taux d’érosion nettement plus faibles, ne dépassant pas 4,5 (t/ha/an). Ainsi, l’érosion globale calculée par pondération des surfaces de production de chaque unité de même sensibilité à l’érosion est estimée à 23 (t/ha/an). D’un autre coté, le taux de sédimentation mesuré dans la retenue du barrage montre que 0,34 cm de sédiments sont déposés chaque année, soit une dégradation spécifique de 50 (t/ha/an)

    Harnessing the potential of African youth for transforming health research in Africa

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    Africa faces a significant burden of infectious diseases, including Malaria and HIV/AIDS, along with an increasing prevalence of non-infectious diseases such as diabetes and cancer. This dual health challenge is amplified by socioeconomic difficulties, restricted access to healthcare, and lifestyle changes, thus present unique scientific needs. Effectively addressing these issues requires a skilled scientific workforce adept in comprehensive healthcare strategies. This analysis explores the critical landscape of health research in Africa, emphasizing the unique opportunity presented by the continent’s youthful population, projected to reach almost 1 billion by 2050. The youth’s innovative potential and fresh perspectives offer a chance to overcome development barriers in health research. Nevertheless, challenges such as under-resourced education, limited research training, inadequate mentorship, and funding difficulties persist. This paper urgently calls upon African leaders, international partners, and stakeholders to prioritize health research, mobilize funding, forge strategic partnerships, and empower the youth as essential steps to capitalize on the continent’s dynamic youth for breakthrough health outcomes. Such investments are vital not just for health but for the overall economic, social, and strategic growth of the continent. Through shared responsibility and a united effort, the potential of African youth can be harnessed, leading to transformative research, improved health outcomes, and a prosperous future. This perspective represents the collective voice of passionate young researchers and advocates across Africa, calling for a new era of health research on the continent

    Investigation of the Antihypertrophic and Antifibrotic Effects of Losartan in a Rat Model of Radiation-Induced Heart Disease

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    Radiation-induced heart disease (RIHD) is a potential late side-effect of thoracic radiotherapy resulting in left ventricular hypertrophy (LVH) and fibrosis due to a complex pathomechanism leading to heart failure. Angiotensin-II receptor blockers (ARBs), including losartan, are frequently used to control heart failure of various etiologies. Preclinical evidence is lacking on the anti-remodeling effects of ARBs in RIHD, while the results of clinical studies are controversial. We aimed at investigating the effects of losartan in a rat model of RIHD. Male Sprague-Dawley rats were studied in three groups: (1) control, (2) radiotherapy (RT) only, (3) RT treated with losartan (per os 10 mg/kg/day), and were followed for 1, 3, or 15 weeks. At 15 weeks post-irradiation, losartan alleviated the echocardiographic and histological signs of LVH and fibrosis and reduced the overexpression of chymase, connective tissue growth factor, and transforming growth factor-beta in the myocardium measured by qPCR; likewise, the level of the SMAD2/3 protein determined by Western blot decreased. In both RT groups, the pro-survival phospho-AKT/AKT and the phospho-ERK1,2/ERK1,2 ratios were increased at week 15. The antiremodeling effects of losartan seem to be associated with the repression of chymase and several elements of the TGF-beta/SMAD signaling pathway in our RIHD model.Peer reviewe
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