831 research outputs found
Influence of decreasing nutrient path length on the development of engineered cartilage
SummaryObjectiveChondrocyte-seeded agarose constructs of 4mm diameter (2.34mm thickness) develop spatially inhomogeneous material properties with stiffer outer edges and a softer central core suggesting nutrient diffusion limitations to the central construct region [Guilak F, Sah RL, Setton LA. Physical regulation of cartilage metabolism. In: Mow VC, Hayes WC, Eds. Basic Orthopaedic Biomechanics, Philadelphia 1997;179â207.]. The effects of reducing construct thickness and creating channels running through the depth of the thick constructs were examined.MethodsIn Study 1, the properties of engineered cartilage of 0.78mm (thin) or 2.34mm (thick) thickness were compared. In Study 2, a single nutrient channel (1mm diameter) was created in the middle of each thick construct. In Study 3, the effects of channels on larger 10mm diameter, thick constructs were examined.ResultsThin constructs developed superior mechanical and biochemical properties than thick constructs. The channeled constructs developed significantly higher mechanical properties vs control channel-free constructs while exhibiting similar glycosaminoglycan (GAG) and collagen content. Collagen staining suggested that channels resulted in a more uniform fibrillar network. Improvements in constructs of 10mm diameter were similarly observed.ConclusionsThis study demonstrated that more homogeneous tissue-engineered cartilage constructs with improved mechanical properties can be achieved by reducing their thickness or incorporating macroscopic nutrient channels. Our data further suggests that these macroscopic channels remain open long enough to promote this enhanced tissue development while exhibiting the potential to refill with cell elaborated matrix with additional culture time. Together with reports that <3mm defects in cartilage heal in vivo and that irregular holes are associated with clinically used osteochondral graft procedures, we anticipate that a strategy of incorporating macroscopic channels may aid the development of clinically relevant engineered cartilage with functional properties
Vortex lattice structures and pairing symmetry in Sr2RuO4
Recent experimental results indicate that superconductivity in Sr2RuO4 is
described by the p-wave E_u representation of the D_{4h} point group. Results
on the vortex lattice structures for this representation are presented. The
theoretical results are compared with experiment.Comment: 4 pages, 3 figures, M2S-HTSC-VI proceeding
MAGMO: polarimetry of 1720-MHz OH masers towards southern star-forming regions
From targeted observations of ground-state hydroxyl (OH) masers towards 702 Methanol Multibeam survey 6.7-GHz methanol masers, in the Galactic longitude range from 186 degrees C through the Galactic Centre to 20 degrees C, made as part of the 'MAGMO' (Mapping the Galactic Magnetic field through OH masers) project, we present the physical and polarization properties of the 1720-MHz OH maser transition, including the identification of Zeeman pairs. We present 10 new and 23 previously catalogued 1720-MHz OH maser sources detected towards star-forming regions (SFRs). In addition, we also detected 16 1720-MHz OH masers associated with supernova remnants and two sites of diffuse OH emission. Towards the 33 star formation masers, we identify 44 Zeeman pairs, implying magnetic field strengths ranging from â11.4 to +13.2 mG, and a median magnetic field strength of |BLOS| ⌠6 mG. With limited statistics, we present the in situ magnetic field orientation of the masers and the Galactic magnetic field distribution revealed by the 1720-MHz transition. We also examine the association statistics of 1720-MHz OH SFR masers with other ground-state OH masers, excited-state OH masers, class I and class II methanol masers, and water masers, and compare maser positions with mid-infrared images of the parent SFRs. Of the 33 1720-MHz star formation masers, 10 are offset from their central exciting sources, and appear to be associated with outflow activity.This work was presented as part of CSOâs doctoral program funded
by the International Macquarie Research Excellence Scholarship
(iMQRES) program. CSO was also a recipient of the Commonwealth Scientific and Industrial Research Organisation (CSIRO)
Astronomy and Space Science Student Program grant for which
CSO is grateful. JRD acknowledges the support of an Australian
Research Council (ARC) DECRA Fellowship (project number
DE170101086). This paper includes archived data obtained through
the Australia Telescope Online Archive (http://atoa.atnf.csiro.au).
The Australia Telescope Compact Array (ATCA) is part of the
Australia Telescope National Facility and funded by the CSIRO.
This research made use of APLPY, an open-source plotting package
for PYTHON (Robitaille & Bressert 2012)
Design and Research of Electron Cyclotron Resonance Heating and Current Dive System on HL-2M Tokamak
A research has been conducted to develop an 8MW electron cyclotron resonance heating and current drive (ECRH/ECCD) system on HL-2M tokamak. The ECRH system compromise eight 1MW gyrotrons, eight evacuated transmission lines and three launchers. The main purpose of the ECRH system was to suppress the neo-classical tearing modes and control the plasma profile. This paper presents an overview of the design and studies performed in this framework. Some primary test results of the critical components have been released in this paper, e.g. polarizers, power monitor and fast steering launchers
Partial wave analysis of J/\psi \to \gamma \phi \phi
Using events collected in the BESII detector, the
radiative decay is
studied. The invariant mass distribution exhibits a near-threshold
enhancement that peaks around 2.24 GeV/.
A partial wave analysis shows that the structure is dominated by a
state () with a mass of
GeV/ and a width of GeV/. The
product branching fraction is: .Comment: 11 pages, 4 figures. corrected proof for journa
Search for the Rare Decays J/Psi --> Ds- e+ nu_e, J/Psi --> D- e+ nu_e, and J/Psi --> D0bar e+ e-
We report on a search for the decays J/Psi --> Ds- e+ nu_e + c.c., J/Psi -->
D- e+ nu_e + c.c., and J/Psi --> D0bar e+ e- + c.c. in a sample of 5.8 * 10^7
J/Psi events collected with the BESII detector at the BEPC. No excess of signal
above background is observed, and 90% confidence level upper limits on the
branching fractions are set: B(J/Psi --> Ds- e+ nu_e + c.c.)<4.8*10^-5, B(J/Psi
--> D- e+ nu_e + c.c.) D0bar e+ e- + c.c.)<1.1*10^-5Comment: 10 pages, 4 figure
Measurements of psi(2S) decays to octet baryon-antibaryon pairs
With a sample of 14 million psi(2S) events collected by the BESII detector at
the Beijing Electron Positron Collider (BEPC), the decay channels psi(2S)->p
p-bar, Lambda Lambda-bar, Sigma0 Sigma0-bar, Xi Xi-bar are measured, and their
branching ratios are determined to be (3.36+-0.09+-0.24)*10E-4,
(3.39+-0.20+-0.32)*10E-4, (2.35+-0.36+-0.32)*10E-4, (3.03+-0.40+-0.32)*10E-4,
respectively. In the decay psi(2S)->p p-bar, the angular distribution parameter
alpha is determined to be 0.82+-0.17+-0.04.Comment: 8 pages, 8 figure
Study of J/psi decays to Lambda Lambdabar and Sigma0 Sigma0bar
The branching ratios and Angular distributions for J/psi decays to Lambda
Lambdabar and Sigma0 Sigma0bar are measured using BESII 58 million J/psi.Comment: 11 pages, 5 figure
Measurements of J/psi Decays into 2(pi+pi-)eta and 3(pi+pi-)eta
Based on a sample of 5.8X 10^7 J/psi events taken with the BESII detector,
the branching fractions of J/psi--> 2(pi+pi-)eta and J/psi-->3(pi+pi-)eta are
measured for the first time to be (2.26+-0.08+-0.27)X10^{-3} and
(7.24+-0.96+-1.11)X10^{-4}, respectively.Comment: 11 pages, 6 figure
BESII Detector Simulation
A Monte Carlo program based on Geant3 has been developed for BESII detector
simulation. The organization of the program is outlined, and the digitization
procedure for simulating the response of various sub-detectors is described.
Comparisons with data show that the performance of the program is generally
satisfactory.Comment: 17 pages, 14 figures, uses elsart.cls, to be submitted to NIM
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