457 research outputs found
Individual heterogeneity generates explosive system network dynamics
Individual heterogeneity is a key characteristic of many real-world systems,
from organisms to humans. However its role in determining the system's
collective dynamics is typically not well understood. Here we study how
individual heterogeneity impacts the system network dynamics by comparing
linking mechanisms that favor similar or dissimilar individuals. We find that
this heterogeneity-based evolution can drive explosive network behavior and
dictates how a polarized population moves toward consensus. Our model shows
good agreement with data from both biological and social science domains. We
conclude that individual heterogeneity likely plays a key role in the
collective development of real-world networks and communities, and cannot be
ignored.Comment: 6 pages, 4 figure
Internal character dictates phase transition dynamics between isolation and cohesive grouping
We show that accounting for internal character among interacting,
heterogeneous entities generates rich phase transition behavior between
isolation and cohesive dynamical grouping. Our analytical and numerical
calculations reveal different critical points arising for different
character-dependent grouping mechanisms. These critical points move in opposite
directions as the population's diversity decreases. Our analytical theory helps
explain why a particular class of universality is so common in the real world,
despite fundamental differences in the underlying entities. Furthermore, it
correctly predicts the non-monotonic temporal variation in connectivity
observed recently in one such system
Atypical viral dynamics from transport through popular places
The flux of visitors through popular places undoubtedly influences viral
spreading -- from H1N1 and Zika viruses spreading through physical spaces such
as airports, to rumors and ideas spreading though online spaces such as
chatrooms and social media. However there is a lack of understanding of the
types of viral dynamics that can result. Here we present a minimal dynamical
model which focuses on the time-dependent interplay between the {\em mobility
through} and the {\em occupancy of} such spaces. Our generic model permits
analytic analysis while producing a rich diversity of infection profiles in
terms of their shapes, durations, and intensities. The general features of
these theoretical profiles compare well to real-world data of recent social
contagion phenomena.Comment: 14 pages, 16 figure
Osseointegrated finger prostheses using a tripod titanium mini-plate
BACKGROUND:
Digital amputation is a common upper extremity injury and can cause significant impairment in hand function, as well as psychosocial stigma. Currently, the gold standard for the reconstruction of such injuries involves autologous reconstruction. However, when this or other autologous options are not available, prosthetic reconstruction can provide a functionally and aesthetically viable alternative. This study describes a novel technique, known as a tripod titanium mini-plate, for osseointegrated digit prostheses, and reviews the outcomes in a set of consecutive patients.
METHODS:
A retrospective review of patients who underwent 2-stage prosthetic reconstruction of digit amputations was performed. Demographic information, occupation, mechanism of injury, number of amputated fingers, and level of amputation were reviewed. Functional and aesthetic outcomes were assessed using the quick disabilities of the arm, shoulder, and hand (Q-DASH) scale and a visual analog scale (VAS) score, respectively. In addition, complications during the postoperative period were recorded.
RESULTS:
Seven patients were included in this study. Their average age was 29 years. Five patients had single-digit amputations and 2 patients had multiple-digit amputations. Functional and aesthetic outcomes were assessed using the Q-DASH score (average, 10.4) and VAS score (average, 9.1), respectively. One episode of mild cellulitis was seen at 24 months of follow-up. However, it was treated successfully with oral antibiotics. No other complications were reported.
CONCLUSIONS:
When autologous reconstruction is not suitable for digit reconstruction, prosthetic osseointegrated reconstruction can provide good aesthetic and functional results. However, larger series with longer-term follow-up are required in order to rule out the possibility of other complications
Anomalous Contagion and Renormalization in Dynamical Networks with Nodal Mobility
The common real-world feature of individuals migrating through a network --
either in real space or online -- significantly complicates understanding of
network processes. Here we show that even though a network may appear static on
average, underlying nodal mobility can dramatically distort outbreak profiles.
Highly nonlinear dynamical regimes emerge in which increasing mobility either
amplifies or suppresses outbreak severity. Predicted profiles mimic recent
outbreaks of real-space contagion (social unrest) and online contagion
(pro-ISIS support). We show that this nodal mobility can be renormalized in a
precise way for a particular class of dynamical networks
Application of the entropy of approximation for the nonlinear characterizationin patients with Chagas disease
Chagas disease American trypanosomiasis is caused by a flagellated parasite: Trypanosoma cruzi, transmitted by an insect of the genus Triatoma and also by blood transfusions. In Latin America, the number of infected people is approximately 6 million, with a population exposed to the risk of infection of 550000. It is our interest to develop a non-invasive and low-cost methodology, capable of detecting any early cardiac alteration that also allows us to see dysautonomia or dysfunction within 24 hours and with this it could be used to detect any cardiac alteration caused by T early Cruzi. For this, we analyzed the 24-hour Holter ECG records in 107 patients with ECG abnormalities (CH2), 102 patients without ECG alterations (CH1) who had positive serological results for Chagas disease and 83 volunteers without positive serological results for Chagas disease (CONTROL). Approximate entropy was used to quantify the regularity of electrocardiograms (ECG) in the three groups. We analyzed 288 ECG segments per patient. Significant differences were found between the CONTROL-CH1, CONTROL-CH2 and CH1-CH2 groups.Postprint (published version
Segmentación de clientes de Corporación Lindley de la región Lima mediante el análisis cluster bietápico en octubre de 2016
El documento digital no refiere asesorDescribe el método del análisis cluster bietápico y su aplicación para segmentar la cartera de clientes de Corporación Lindley de la región Lima en octubre de 2016. El método de análisis cluster bietápico es una herramienta de exploración diseñada para descubrir las agrupaciones naturales (o conglomerados) de un conjunto de datos. Este método combina los métodos jerárquicos y no jerárquicos (o de partición) permitiendo analizar a la vez variables de distinto tipo (categóricas y continuas) y puede ser utilizado en bases de datos grandes.Trabajo de suficiencia profesiona
Marketing relacional y fidelización de clientes en tiempos de pandemia la empresa Coorporation Interpharma SAC, Lima, 2021
La presente investigación titulada: Marketing Relacional y Fidelización de Clientes
en tiempos de pandemia la Empresa Coorporation Interpharma SAC, Lima, 2021,
tuvo como objetivo general determinar la relación que existe entre Marketing
Relacional y Fidelización de Clientes en tiempos de pandemia la Empresa
Coorporation Interpharma SAC, Lima, 2021. Los instrumentos que se utilizaron
fueron cuestionarios en escala de Likert para las variables Marketing Relacional y
Fidelización. Estos instrumentos fueron sometidos a los análisis respectivos de
confiabilidad y validez, que determinaron que los cuestionarios tienen validez y
confiabilidad. El método empleado fue hipotético deductivo, el tipo de investigación
fue básica, de nivel correlacional, de enfoque cuantitativo; de diseño no
experimental. La población estuvo conformada por 150 y muestra 108 clientes de
la empresa Coorporation Interpharma SAC, Lima. La técnica empleada para
recolectar información fue encuesta y los instrumentos de recolección de datos
fueron cuestionarios que fueron debidamente validados a través de juicios de
expertos y su confiabilidad a través del estadístico de fiabilidad Alfa de Cronbach.
En el resultado se observa que Marketing Relacional y Fidelización están
correlacionados altamente en la Empresa Coorporation Interpharma SAC, Lima,
2021 (rs= 0,816, sig= 0,000 < 0.05), en tanto, es rechazada la hipótesis nula y se
acepta la hipótesis general
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