Optimal Design of Filament Wound Grid-stiffened Composite Cylindrical Structures

An integral account of design and analysis of grid-stiffened cylindrical structures is presented. For convenience, a two-phase approach is adopted. In the initial phase, with a view to arriving at a few initial possible optimal configurations, parametric analysis through smeared stiffeners approach is utilised. The ribs, in a filament wound grid-stiffened structure, introduce several additional design elements that result in many possible design configurations; in the initial phase, these design options are efficiently reduced to a few numbers. Finite element modelling is used in the final design and analysis. Rib material is distinct from normal unidirectional composites and this aspect is inherently accounted for in the modelling approaches considered here.Defence Science Journal, 2011, 61(1), pp.88-94, DOI:http://dx.doi.org/10.14429/dsj.61.48

Cephalopod fishery off Thoothukudi coast, Tamil Nadu

In Thoothukudi district of Tamil Nadu, cephalopod resources are principally exploited by single day trawlers followed by hook and line. During 2012-18, nearly 54% of cephalopods landed were caught by mechanised trawl net; 32% by outboard crafts operating hook and line, 8% by gill net and rest by other gears. From 2012-18, the cephalopod landing showed a fluctuating trend and major cephalopod species landed by trawl net were Sepia pharaonis, S. prabahari, Sepioteuthis lessoniana, Uroteuthis (P) singhalensis and U. (P) duvaucelii. In hook and line, S. pharaonis was the dominant species followed by S. lessoniana and Octopus cyanea

Integrating IoT and Novel Approaches to Enhance Electromagnetic Image Quality using Modern Anisotropic Diffusion and Speckle Noise Reduction Techniques

Electromagnetic imaging is becoming more important in many sectors, and this requires high-quality pictures for reliable analysis. This study makes use of the complementary relationship between IoT and current image processing methods to improve the quality of electromagnetic images. The research presents a new framework for connecting Internet of Things sensors to imaging equipment, allowing for instantaneous input and adjustment. At the same time, the suggested system makes use of sophisticated anisotropic diffusion algorithms to bring out key details and hide noise in electromagnetic pictures. In addition, a cutting-edge technique for reducing speckle noise is used to combat this persistent issue in electromagnetic imaging. The effectiveness of the suggested system was determined via a comparison to standard imaging techniques. There was a noticeable improvement in visual sharpness, contrast, and overall clarity without any loss of information, as shown by the results. Incorporating IoT sensors also facilitated faster calibration and real-time modifications, which opened up new possibilities for use in contexts with a high degree of variation. In fields where electromagnetic imaging plays a crucial role, such as medicine, remote sensing, and aerospace, the ramifications of this study are far-reaching. Our research demonstrates how the Internet of Things (IoT) and cutting-edge image processing have the potential to dramatically improve the functionality and versatility of electromagnetic imaging systems

Effect of drought on gas exchange and chlorophyll fluorescence of groundnut genotypes

Drought is one of the major threats to groundnut productivity, causing a greater loss than any other abiotic factor. Water stress conditions alter plant photosynthetic activity, impacting future growth and assimilating mobilization towards sink tissues. The purpose of this study was to investigate how drought impacts the photosynthesis of plants and its links to drought tolerance. The influence of reproductive stage drought on photosynthetic activity and chlorophyll fluorescence of groundnut is well studied. The experiment was conducted in Kharif 2019 (Jul-Sep), where recent series in groundnut genotypes (60 nos) sown under rainfed conditions and water stress was created by withholding irrigation for 20 days between 35-55 days after sowing in the field to simulate drought conditions. Imposition of water deficit stress reduced PS II efficiency, which significantly altered the photosynthetic rate in the leaf. Observation of gas exchange parameters viz., photosynthetic rate, stomatal conductance and transpiration rate after 20 days of stress imposition revealed that of all 60 genotypes, 20 genotypes (VG 17008, VG 17046VG 18005, VG 18102, VG 18077, VG 19572, VG 19709, VG 18111, VG19561, VG19576, VG 19620, VG 19681, VG 19688, etc.,) had better Photosynthetic rate, Stomatal conductance. Similarly, PS II efficiency analyzed through fluorescence meter revealed that among the 60 and all the genotypes given above recorded higher value in Fv/Fm. Results obtained from Cluster analysis and PCA confirmed that photosynthetic rate and Fv/Fm is useful parameter in screening adapted cultivars under drought stress. These findings lay the groundwork for a future study to decipher the molecular pathways underpinning groundnut drought resistance

Design and Fabrication of Self-Charging Bi-Cycle with Power Saving Application using Solar Panel

With the increase in fuel prices, pollution content in atmosphere and due to gradual end of the nonrenewable sources of energy we have to alter the source of our energy in our vehicles. Now a day’s Bicycles are more commonly used by the youngsters and school students.  At the same time demand of electricity is vital problem in these days and that of the humans becoming tired when pedalling the bicycles to reduce all these problems. We are implementing a self-charging bicycle. The model converts mechanical energy into electrical energy without pollution.

The δ‐opioid receptor positive allosteric modulator BMS 986187 is a G‐protein‐biased allosteric agonist

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149355/1/bph14602.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149355/2/bph14602_am.pd

Soil Structure Interaction of Framed Structure Supported on Non- Homogeneity of Soil Condition

Soil often exhibits non – homogeneity, due to this non – homogeneity, different settlement occurs. This cause changes in the moments and forces in the members of superstructure frames. The order of magnitude of these changes is not known. In this paper, plane frames with differential configuration have been analysed taking into account soil- structure interaction using Finite Element Method. For the present study soil having different stiffnesses in the right and left half below the structure is considered and the effect of this  non – homogeneity on superstructure forces having presented, for plane frames with number of bays varying from 3,5,7 and number of storeys 1to 6. The young’s modulus ratio of soil for right and left half has been varied from 1 to 7.5. To non – homogeneity of soil increases the forces in peripheral columns and beams, which were found to be already critical even for homogeneity soil condition. Hence, in general, it is concluded at non – homogeneity of soil increases the effect of soil interaction on the super structure forces

Effect of drug-to-lipid ratio on nanodisc-based tenofovir drug delivery to the brain for HIV-1 infection

Background: Combination antiretroviral therapy has significantly advanced HIV-1 infection treatment. However, HIV-1 remains persistent in the brain; the inaccessibility of the blood–brain barrier allows for persistent HIV-1 infections and neuroinflammation. Nanotechnology-based drug carriers such as nanodiscoidal bicelles can provide a solution to combat this challenge. Methods: This study investigated the safety and extended release of a combination antiretroviral therapy drug (tenofovir)-loaded nanodiscs for HIV-1 treatment in the brain both in vitro and in vivo. Result: The nanodiscs entrapped the drug in their interior hydrophobic core and released the payload at the desired location and in a controlled release pattern. The study also included a comparative pharmacokinetic analysis of nanodisc formulations in in vitro and in vivo models. Conclusion: The study provides potential applications of nanodiscs for HIV-1 therapy development