New Enzymatic Gel as Adjuvant Treatment for Wound Healing Processes in Oral Surgery, A Mini-Review and A Case Report

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Rilievo 3D non a contatto: tecniche speciali per l'arte rupestre

Dal punto di vista dell’arte rupestre, le metodologie di ricostruzione tridimensionale offrono la possibilità di studiare dettagliatamente, eseguire i rilievi ed archiviare digitalmente incisioni e reperti nella loro completezza. Viene proposta una tecnica fotogrammetrica (Photometric Stereo) di estrema semplicità durante la fase di acquisizione, rapidità di elaborazione e dai costi nettamente contenuti rispetto all’utilizzo dei laser scanner. A differenza di altre tecniche fotogrammetriche, la Photometric Stereo utilizza una fotocamera standard fissa per acquisire più immagini sotto angoli di illuminazione differenti. L’elaborazione delle immagini permette la ricostruzione di un modello 3D ad alta risoluzione, con tutte le incisioni da pochi micron di spessore in su. Viene restituita inoltre una mappatura dell’albedo, ovvero il colore puro della superficie senza il contributo delle ombreggiature. La superficie 3D, ricolorata con l’albedo, fornisce ricostruzioni virtuali di grande naturalezza.From the point of view of the rock art, the 3D reconstruction methodologies oer the possibility of a meticulous study of the findings and engravings, with the complete relief and electronic storage of all the data. Here is proposed a photogrammetric technique, very easy for dataset acquisition, really fast during the elaboration process and really cheaper than the laser scanner. Contrary to the other photogrammetric techniques, the Photometric Stereo needs some shots taken with a reflex camera in a fixed position on a tripod, from some different lighting angle. The data elaboration gives back a high resolution 3D model, with all the engravings from few micron thickness. The processing also reconstructs the albedo, that is the pure surface color without any shadow. The 3D surface, after the albedo coloring, appears like a really genuine virtual reconstruction

Photometric Stereo 3D visualizations of rock-art panels, bas-reliefs and graffiti

For small scale cultural subjects, as rock engravings, graffiti and bas-reliefs, the 3D rendering may be realized by applying the photometric stereo consolidate method, instead of complex and expensive laser-scanning equipments. It is a cheap, portable and easily implementable technique generally used in quality controls within manufacturing industrial environments or in robotic vision. Its main advantage is the use of common digital photography with portable flash lighting and dedicated software for data elaboration. Furthermore, it provides as output data, in addition to the morphological information of the objects, the map of brightness and surface colours (albedo), which allows the user to correctly recognize the frescoes and paintings without affections of shadows and surface distortions. This communication deals with theoretical fundamentals of the photometric stereo method for 3D rendering of surfaces, its practical implementation and the mathematical strategies to obtain the both the morphological data and the albedo functions. Some examples of applications on rock-art and other artefacts are presented and discussed

Photometric stereo 3D visualizations of rock-art panels, bas-reliefs, and graffiti

For small-scale cultural subjects, such as rock engravings, graffiti and bas-reliefs, 3D rendering may be realized by applying the photometric stereo consolidate method, instead of complex and expensive laser-scanning equipments. It is a cheap, portable, and easily implementable technique generally used in quality controls within manufacturing industrial environments or in robotic vision. Its main advantage is the use of common digital photography with portable flash lighting and dedicated software for data elaboration. Furthermore, it provides as output data, in addition to the morphological information of the objects, the map of brightness and surface colours (albedo), which allows the user correctly to identify the frescoes and paintings without distortions caused by shadows or other morphological detail. This paper deals with the theoretical fundamentals of the photometric stereo method for 3D rendering of surfaces, its practical implementation, and the mathematical strategies to obtain both the morphological data and the albedo functions. Some examples of applications on rock-art and other artefacts are presented and discussed

Recognition of ZnT8, Proinsulin, and Homologous MAP Peptides in Sardinian Children at Risk of T1D Precedes Detection of Classical Islet Antibodies

As numerous studies put in evidence the increasing incidence of type 1 diabetes (T1D) in children, an early diagnosis is of great importance to define correct treatment and diet. Currently, the identification of classical islet autoantibodies is the primary biomarker for diagnosis in subjects at risk, especially in pediatric patients. Recent studies suggest that detection of antibodies against ZnT8 protein in preclinical phase can predict the development of T1D. We previously demonstrated a significant association of Mycobacterium avium subspecies paratuberculosis (MAP) with T1D in adult Sardinian patients. To enforce this finding, we investigated the presence of antibodies against ZnT8 and proinsulin (PI) with respective homologous epitopes: MAP3865c133–141/ZnT8186–194, MAP3865c125–133/ZnT8178–186, MAP2404c70–85/PI46–61, and MAP1,4αgbp157–173/PI64–80, in 23 children at risk for T1D, formerly involved in the TRIGR study, and 22 healthy controls (HCs). Positivity to anti-MAP and homologous human peptides was detected in 48% of at-risk subjects compared to 5,85% HCs, preceding appearance of islet autoantibodies. Being MAP easily transmitted to humans with infected cow’s milk and detected in retail infant formulas, MAP epitopes could be present in extensively hydrolyzed formula and act as antigens stimulating β-cell autoimmunity

Regression analysis between T1D incidence rate and Co, Cr, Cu, Mn, Pb, Zn.

<p>On the X axis the geochemical elements value (ppm) is reported; on the Y axis is reported T1D incidence rate normalized by Homogeneous Areas (HA). For each element the correlation coefficient, R, and the respective P value are shown.</p

Correlation coefficients between geochemical elements.

<p>Correlation coefficients between geochemical elements.</p

(A and B): Spatial distribution of T1D incidence rate and Co, Cr, Cu, Mn, Pb, Zn values in Sardinia.

<p>The results relate to 109 Homogeneous Areas (HA) identified from the lithological point of view. T1D incidence rate is represented by a chromatic scale, dividing values into three ranges, as indicated in the legend. Circles size symbolizes the amount of metal (ppm) detected in stream sediments samples, according to three ranges listed in the legend.</p