Modelling of E-Governance Framework for Mining Knowledge from Massive Grievance Redressal Data

With the massive proliferation of online applications for the citizens with abundant resources, there is a tremendous hike in usage of e-governance platforms. Right from entrepreneur, players, politicians, students, or anyone who are highly depending on web-based grievance redressal networking sites, which generates loads of massive grievance data that are not only challenging but also highly impossible to understand. The prime reason behind this is grievance data is massive in size and they are highly unstructured. Because of this fact, the proposed system attempts to understand the possibility of performing knowledge discovery process from grievance Data using conventional data mining algorithms. Designed in Java considering massive number of online e-governance framework from civilian’s grievance discussion forums, the proposed system evaluates the effectiveness of performing datamining for Big data

Experimental studies on the energy absorption capacity of axially compressed metal tubes

Impact energy absorbers are expendable mechanical structural elements, which are brought into action to dissipate the kinetic energy in the event of an unwanted collision. These act as mechanical fuses to limit the loads, which may act on the main structure immediately after a collision. The use of aluminium tubes and tubular structures for use as impact energy absorbers in different engineering applications is encouraging. This is because of their ready availability in different cross sections and sizes, and also has high energy absorption capacity under quasi-static and dynamic loads. In this present study, experiments are conducted on circular aluminium tubes under quasi-static, axial compression. The different modes of deformation of these tubes are examined in two separate cases. Case 1: when the tubes compressed axially between a flat platen and shaped dies of different radii. Case 2: when the tubes compressed axially between two flat platens. Dies of different radii are used to evaluate the efficient mode of deformation. The energy absorption capacity under quasi-static loading conditions is evaluated in the above cases to evaluate the energy absorption capacity and to compare the energy absorption of aluminium tubes based on the different deformation modes. The results of the study are useful in the design of impact energy absorbers © IAEME Publicatio

Fabrication of Poly (Evans Blue) Modified Graphite Paste Electrode as an Electrochemical sensor for Sensitive and Instant Riboflavin Detection

Electro-analysis of Riboflavin (RN) consumed as vitamin has been delved by constructing the poly (Evans Blue) modified graphite paste electrode (PEBMGPE) as an electrochemical detector. Voltammetric determination of RN in 0.2 M PBS (pH 7.0) at the electro-active layer of the PEBMGPE was conducted. The PEBMGPE plays a crucial role as sensing tool towards the detection of RN compared to the BGPE. The topographical features of the bare graphite paste electrode (BGPE) and PEBMGPE was acquired by the FESEM surface analysis. All experimental factors such as applied potential, the effect of scan rate, impact of the pH were optimized. Employing the Differential pulse voltammetry (DPV) approaches using the good experimental circumstances the analytical curve was linear in the range of 6×10-6-1.5×10-4 M,  the detection limit and limit of quantification gained as 2.1×10-7 M and 7.1×10-7 M, respectively. Subsequently, good repeatability, excellent reproducibility, and adequate stability, high sensitivity were achieved for the PEBMGPE sensor. In addition, the PEBMGPE sensor was applied for the interference study of RN with Dopamine (DA) and Paracetamol (PR). Besides the practicability of the projected sensor was successfully utilized for the detection of the RN in the pharmaceutical formulation

Polymethionine modified carbon nanotube sensor for sensitive and selective determination of L-tryptophan

The electrochemically initiated catalytic oxidation of amino acid L-tryptophan (L-TPN) in phosphate buffer solution has been scrutinized using highly conductive polymethionine modified carbon nanotube paste sensor (PMETCNTPS) through cyclic voltammetry (CV) technique. Compared to the bare carbon nanotube paste sensor (BCNTPS), PMETCNTPS exhibited a quantifiable current signal by CV method. PMETCNTPS was found sensitive to L-TPN concentrations within the linear segment of detection range 1.5 - 8.0×10-5 M. By employing the calibration plot, the detection limit was determined as 6.99×10-7 M. In addition, PMETCNTPS was successfully exploited and validated in determining L-TPN in the pharmaceutical supplement.</p

Enhanced voltammetric detection of paracetamol by using carbon nanotube modified electrode as an electrochemical sensor

New aspects associated with electro-catalytic activity of poly(methyl orange) modified carbon nanotube paste electrode (PMMCNTPE)towards the detection of paracetamol (PC) which is typically used worldwide as a pain reliever, were explored through implementation of cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. Bare carbon nanotube paste electrode (BCNTPE) was modified by methyl orange using the electropolymerizing method. The effect of pH and influence of potential scan rate were resolved by means of CV technique. It was found that under optimized experimental conditions, PMMCNTPE imparts the analytical curve for PC in the concentration range of 2.0×10-6 – 5.0×10-5 M with detection limit of 3.8×10-8 M and limit of quantification of 1.2×10-8 M. The proposed sensor exhibited acceptable reproducibility, admirable stability, and adequate repeatability. The interference study of PC with dopamine (DA) and folic acid (FA) showed good selectivity of the designed sensor. The feasibility of the constructed electrochemical sensor to detect PC was successfully tested in some pharmaceutical formulations

A study on patients treated with interlock nailing in the forearm fracture bones

Background: Fractures involving the bones of the forearm present unique problems not encountered with fractures of other long bones and may significantly affect the function of the upper limb. The purpose of the present study was to evaluate the functional outcome of patients treated with interlock nailing in the fracture forearm bones.Methods: Thirty two patients included after their consent. With the patient supine on a radiolucent table, and under general or regional anesthesia the extremity was prepared and the surgery was performed using a standard procedure. If secure rigid fixation is achieved forearm POP splint is applied and kept in place for 2 weeks, thereafter a removable sugar-tong orthosis is worn until bridging callus is present, and the orthosis is removed frequently for exercise.Results: The average age of the patients was 38.90 years. The major mode of injury was RTA (59.09%) followed by assault (36.36%). 41% of patients were operated within week of injury, only three patients were operated after a week and one patient after 3 weeks. More than half of patients had closed fractures and rest was open fractures, of which Gustilo Anderson type II were in majority. In 3/5 of patients locking at nondriving end was not done cause of stable fixation. There was statistically significant difference in the surgical time (P &lt;0.05) and duration of postoperative immobilization differed statistically significantly (P &lt;0.001) between the group of patients in whom locking was done and not done. Conclusions: Advantages of Interlocking nail are high rate of bony consolidation along with minimized surgical approaches, cosmetically better suited and little risk of refracture after removal of the implant

Evaluation of fungal pathogens, Fusarium semitectum Berk. and Ravenel and Hirsutella thompsonii Fisher against red spider mite, Tetranychus neocaledoni-cus (Andre) of okra under laboratory and greenhouse conditions

Efficacy of fungal pathogens, Fusarium semitectum Berk. and Ravenel and Hirsutella thompsonii Fisher was evaluated against red spider mite, Tetranychus neocaledonicus (Andre) of okra under laboratory and greenhouse conditions. Among the treatments evaluated under laboratory conditions, the highest mortality of 78.20 and 88.34 percent adults and immatures, respectively was recorded at 2.10 x 109 spores per ml of F. semitectum, whereas it was 82.05 and 92.31 per cent adults and immatures, respectively in case of H. thompsonii at 4.60 x 108 spores per ml. Among the twelve treatments evaluated under greenhouse conditions, H. thompsonii 4.60 x 108 spores per ml, F. semitectum 2.10 x 109 spores per ml + H. thompsonii 4.60 x 108 spores per ml, H. thompsonii 4.60 x 108 spores per ml + dicofol 0.025% and F. semitectum 2.10 x 109 spores per ml + H. thompsonii 4.60 x 108 spores per ml + dicofol 0.025% were found to be on par with each other with a cumulative percent mortality of 81.20, 81.48, 81.21 and 82.59 percent, respectively. By testing the field efficacy of F. semitectum and H. thompsonii against T. neocaledonicus, these fungal pathogens can be used as potential biocontrol agents for the sustainable management of mites on okra. Hence the present study evaluates the potentiality of F. semitectum for the management of T. neocaledonicus by comparing with the well-known acaricidal fungus, H. thompsonii

PROTECTIVE EFFECT OF COMMIPHORA MUKUL GUM RESIN ON BRAIN IN STREPTOZOTOCIN-INDUCED DIABETIC RATS

Objective: The present study was undertaken to investigate the hypolipidemic activity of ethanolic extract of Commiphora mukul gum resin (EtCMGR) on the brain of streptozotocin (STZ) induced diabetic Wistar rats.Methods: Thirty two rats, included for the study, were divided into four groups: control (C), control treated with EtCMGR (C+CM), diabetic (D) and diabetic treated with EtCMGR (D+CM). Diabetes was induced by single intraperitonial injection of STZ (55 mg/kg b.w.).Results: Diabetic rats showed significant reduction in the levels of total lipids, phospholipids, cholesterol, glycolipids and protein level and significant decrease in the activity of acetylcholinesterase while the levels of triglycerides, acetylcholine and the activities of glutamate pyruvate transaminases (GPT) and glutamate oxaloacetate transaminases (GOT) increased significantly when compared to control group. Oral administration of EtCMGR (suspended in 5% Tween-80 in distilled water prior to use) daily at a concentration of 200 mg/kg b.w. to group-D+CM rats for 60 days reversed the above changes significantly.Conclusion: These results suggest that EtCMGR exhibits hypolipidemic effect in the STZ-induced diabetic rats.Â

Research developments in carbon materials based sensors for determination of hormones

Various carbon-based sensors (graphene, carbon nanotubes, graphite, pencil graphite, glassy carbon, etc.) have distinctive behavior and a broad range of importance for identifying sex hormones like estriol, estradiol, estrone, progesterone, and testosterone. The current review emphasizes voltammetric, amperometric, and electrochemical impedance spectroscopic methods for detecting some of these hormones. The existence, structural aspects, nature, and biological importance of each hormone were analyzed in detail and their analysis with different electroanalytical methods was considered. Unique methodologies and innovations of electrochemical sensors for hormones based on carbon materials modified by different agents were examined. In this review, the interaction among various sensor materials and analytes in different supporting electrolyte media is premeditated. The most important significances of the electroanalytical methodologies were discussed based on sensor selectivity, sensitivity, stability, the limit of detection, repeatability, and reproducibility