Kinetics of Acid-catalysed Hydrolysis of Hexanohydroxamic Acid

1086-108

Improving I/O Performance using Cache as a Service on Cloud

Caching is gaining popularity in Cloud world. It is one of the key technologies which plays a major role in bridging the performance gap between memory hierarchies through spatial or temporal localities. In cloud systems, heavy I/O activities are associated with different applications. Due to heavy I/O activities, performance is degrading. If caching is implemented, these applications would be benefited the most. The use of a Cache as a Service (CaaS) model as a cost efficient cache solution to the disk I/O problem. We have built the remote-memory based cache that is pluggable and file system independent to support various configurations. The cloud Server process introduce, pricing model together with the elastic cache system. This will increase the disk I/O performance of the IaaS, and it will reduce the usage of the physical machines. DOI: 10.17762/ijritcc2321-8169.150516

Effect of remdesivir on mortality rate, need of intubation and mechanical ventilation in COVID-19 positive patients: a retrospective observational study

Background: The symptoms of SARS-CoV-2 infection vary widely, from asymptomatic disease to pneumonia and life-threatening complications, including acute respiratory distress syndrome, multisystem organ failure, and ultimately, death. Remdesivir has broad spectrum of activity against members of several virus families, including filoviruses and coronaviruses. Remdesivir is a potent inhibitor of SARS-CoV-2 replication in human nasal and bronchial cells. Methods: This is a prospective and observational study conducted in patients of either gender, age more than 18 years with confirmed diagnosis of COVID-19 by RT-PCR. A predesigned, pretested and semi structured questionnaire containing socio demographic details like age, sex, BMI, comorbidities, findings of systemic examination of the cases, dose and duration of Remdesivir received and adverse effect due to therapy was used to collect the data. Results: Mean age of the patients were 56.19±10.93 years. Male patients were 66% and 34% patients were female. After receiving the remdesivir, 43% of the patients needed bag mask and 27% of the patients maintained on room air oxygen. Non-invasive ventilation required in 19% of the patients and 11% of the patient required mechanical ventilation. s14% of the patients needed admission in the ICU. 3.5% of the patients were died and 96.5% patients were discharged from the hospital. Conclusions: Remdesivir reduces the need of non-invasive oxygenation and mechanical ventilation. Mortality was seen in 3.5% patients, henceforth remdesivir, is an effective drug for moderate to severe COVID-19, if given in early stages of infection

Clostridium difficile in Antibiotic-Associated Diarrhoea and Detection of Toxin Producing Strains in a Tertiary Care Hospital in Western Maharashtra

Background: Rampant and injudicious use of broad spectrum antibiotic in hospitalized patients has increased the incidence of Clostridium difficile Associated Diarrhea (CDAD). In recent years, Clostridium difficile Infection (CDI) has become more frequent, severe, and difficult to treat. Aim and Objective: A prospective, study was conducted to isolate C. difficile in Antibiotic-associated Diarrhoea (AAD) and to detect toxin producing strains of C. difficile from faecal samples of patients suspected to have CDI. Material and Methods: A total of 111 hospitalized patients who developed diarrhoea after >72 hours of admission and suspected of CDI were enrolled for investigation. The samples were subjected to anaerobic culture and toxin assay. Results: The total sample size of the study was 111 patients who were having antibiotic associated diarrhoea. Majority of the patients were from the age group 21-30 years and 41-50 years i.e., 23 (20.7%). Males 64 (57.7%) were affected more as compared to females 47 (42.3%). Third generation cephalosporins were the most common group of antibiotics associated with both AAD 36 (32.4%) and CDAD 9 (42.85%) cases, followed by carbapenem fluroquinolones in combination 3 (12.5%). Culture positivity was seen in 12 (10.81%) of the 111 stool samples and 39 (35.13%) were toxin producers. Conclusion: The use of several medications was found to be associated with an increased risk of CDAD. The only way to reduce Cl. difficile infection is to judiciously use antibiotics, strictly adhere to antibiotic policy and to give prime importance to strict infection control measures

Snake Bite Complicated By Bacterial Meningitis

Background: Neurotoxic snake bite envenomation is a common life threatening medical emergency in India, especially in the rural areas. Case Presentation: We report a case of a neurotoxic snake envenomation presenting with abdominal pain and neuromuscular paralysis, which developed bacterial meningitis during her stay in the hospital. Possibly, secondary to the snake bite, a very rare incidence. Conclusion: Our case is a step towards the direction pointing to the rare possibility of bacterial meningitis complicating snake bites which needs further research

Effect of varying concentrations of salinity on some biochemical parameters involved in nitrogen metabolism of four grass species

ABSTRACT: Salinity adversely affects crop productivity and the quality of yield. The present work was carried out to estimate the changes in nitrogen metabolism under the influence of NaCl salinity in four selected grasses. All the species recorded a decrease in nitrate nitrogen content at the highest concentration of salinity stress (300 mM). Its maximum increase was 14 and 19% (100 mM) for Cymbopogon nardus and Cynodon dactylon, respectively. The maximum increase in nitrite nitrogen found was 11% (200 mM) in Cymbopogon nardus, 12% (100 mM) in Cynodon dactylon. The concentration of proline and amides in the leaves of all the experimental grasses showed a positive correlation with increasing concentrations of salinity. The maximum increase in proline content was 81, 88, 126, and 68% in Cymbopogon nardus, Cynodon dactylon, Pennisetum alopecuroides, and Vetiveria zizanioides, respectively, at 300 mM NaCl salinity. The concentration of free amino acids in the leaves of all the experimental grasses was considerably increased under saline condition and showed a positive correlation with increasing concentrations of salinity. Similar results were obtained in the case of amides. The concentration of nitrate reductase enzyme was elevated in Cymbopogon nardus and Pennisetum alopecuroides at lower salinity regime

New Constraints on Dispersive Form Factor Parameterizations from the Timelike Region

We generalize a recent model-independent form factor parameterization derived from rigorous dispersion relations to include constraints from data in the timelike region. These constraints dictate the convergence properties of the parameterization and appear as sum rules on the parameters. We further develop a new parameterization that takes into account finiteness and asymptotic conditions on the form factor, and use it to fit to the elastic \pi electromagnetic form factor. We find that the existing world sample of timelike data gives only loose bounds on the form factor in the spacelike region, but explain how the acquisition of additional timelike data or fits to other form factors are expected to give much better results. The same parameterization is seen to fit spacelike data extremely well.Comment: 24 pages, latex (revtex), 3 eps figure

Morphological features of human mandible

Abstract: Next to pelvis, the skull is the most easily sexable portion of the skeleton. As a component of the skull, mandible shares its own characteristics, but its indices for sex determination are neither as abundant as those of the skull. Mandible is the strongest and largest bone of the skull. It shows various morphological features which may shows changes with references to age, sex and race. The present study was undertaken to obtain the information on variation of lingua and coronoid process, distribution of genial tubercles and presence or absence of median pit. The material for this study comprised of a collection of 84 (168 sides) dry adult human mandibles obtained from Bone bank available in the department of Anatomy, Goverenment medical college, Aurangabad. Triangular shaped lingulae were found in 80 (47.67%) sides, truncated in 18 (10.71%) sides, nodular in 47 (27.97%) and assimilated in 23(13.69%) sides. Triangular lingulae were found bilaterally in 32, truncated in 4, nodular in 19 and assimilated in 8 mandibles. Triangular coronoid process was found more in male bones (62 sides). Pattern of Type II genial tubercle (41 mandibles) was found to be most prevalent. In Summary types of lingula and coronoid process can be used for sexing of mandible