Understanding Professional Sport Organizations Use of Facebook

Facebook has rapidly grown since its inception in 2004. Due to this the purpose of this study is to find out what sport organizations are doing to interact with fans on their Facebook pages. Content analysis was performed to place 930 Facebook posts by sport organizations into one of four categories: interactivity, diversion, content, and promotional (Table-1). This research is important because social media is a growing industry. The study of NFL teams concluded 49% Content, 33% Interactivity, 11% Diversion, and 8% Promotional. The study of NHL teams concluded 35% Content, 17% Interactivity, 34% Diversion, and 14% Promotional

Design of an RSFQ Control Circuit to Observe MQC on an rf-SQUID

We believe that the best chance to observe macroscopic quantum coherence (MQC) in a rf-SQUID qubit is to use on-chip RSFQ digital circuits for preparing, evolving and reading out the qubit's quantum state. This approach allows experiments to be conducted on a very short time scale (sub-nanosecond) without the use of large bandwidth control lines that would couple environmental degrees of freedom to the qubit thus contributing to its decoherence. In this paper we present our design of a RSFQ digital control circuit for demonstrating MQC in a rf-SQUID. We assess some of the key practical issues in the circuit design including the achievement of the necessary flux bias stability. We present an "active" isolation structure to be used to increase coherence times. The structure decouples the SQUID from external degrees of freedom, and then couples it to the output measurement circuitry when required, all under the active control of RSFQ circuits. Research supported in part by ARO grant # DAAG55-98-1-0367.Comment: 4 pages. More information and publications at http://www.ece.rochester.edu:8080/users/sde/research/publications/index.htm

Response of Gram-positive bacteria to copper stress

The Gram-positive bacteria Enterococcus hirae, Lactococcus lactis, and Bacillus subtilis have received wide attention in the study of copper homeostasis. Consequently, copper extrusion by ATPases, gene regulation by copper, and intracellular copper chaperoning are understood in some detail. This has provided profound insight into basic principles of how organisms handle copper. It also emerged that many bacterial species may not require copper for life, making copper homeostatic systems pure defense mechanisms. Structural work on copper homeostatic proteins has given insight into copper coordination and bonding and has started to give molecular insight into copper handling in biological systems. Finally, recent biochemical work has shed new light on the mechanism of copper toxicity, which may not primarily be mediated by reactive oxygen radical

La compétence relative au droit au retour au travail du travailleur accidenté : valse-hésitation entre l'arbitre de grief et la commission des lésions professionnelles

Le handicap au travail est en soi un phénomène récurrent dans le milieu du travail. Le législateur québécois a mis en place, depuis le dernier siècle, une série de protections législatives pour permettre aux travailleurs de maintenir leur lien d'emploi, tout en étant incapable de fournir leur prestation de travail de manière adéquate et régulière, allant à l'encontre de la définition classique de la relation contractuelle entre employeur et travailleur au sens du Code civil du Québec. Ainsi, la Loi sur les accidents du travail et les maladies professionnelles protègent les travailleurs en cas d'incapacité d'effectuer leur prestation de travail tout en leur garantissant un droit au retour au travail, selon les modalités prévues à la loi. Les travailleurs bénéficient également d'une autre protection, soit le droit à l'égalité à l'emploi en vertu de la Charte des droits et libertés de la personne. De part cette protection quasi-constitutionnelle, l'employeur est dans l'obligation de fournir un accommodement raisonnable au travailleur handicapé afin de lui permettre de retourner au travail en tenant compte de ses limitations fonctionnelles. Aujourd'hui, la portée de l'obligation d'accommodement de l'employeur se retrouve dans un débat très animé devant les tribunaux d'arbitrage. Depuis les quinze dernières années, un débat a surgi dans la jurisprudence arbitrale sur la portée de l'obligation d'accommodement de l'employeur dans des dossiers impliquant des travailleurs qui demeurent avec des limitations fonctionnelles en raison d'une lésion professionnelle. Est-ce que cette question doit être tranchée par les arbitres de grief ou plutôt par les organismes en charge du régime d'indemnisation des lésions professionnelles, soit la Commission de la santé et de la sécurité du travail et la Commission des lésions professionnelles? L'objectif de cette étude est d'analyser la compétence des arbitres de grief, plus particulièrement dans des dossiers impliquant des situations où les travailleurs ont déjà reçu une décision de la part de la CSST ou de la CLP leur indiquant que l'employeur n'avait pas d'emploi convenable à leur offrir, et ce, entre autres à partir d'une étude détaillée de la jurisprudence arbitrale. Ainsi, nous espérons apporter un éclairage supplémentaire aux débats à ce sujet. D'abord nous dresserons un canevas des différentes notions juridiques, soit la notion de handicap, la notion d'accommodement et la notion du droit au retour au travail pour les travailleurs atteints d'une incapacité physique ou psychologique, soit en raison d'une lésion professionnelle, soit pour une autre raison. Ensuite, nous expliquerons les compétences respectives de l'arbitre de grief, de la Commission de la santé et de la sécurité du travail et de la Commission des lésions professionnelles en matière d'obligation d'accommodement et du droit au retour au travail afin de comprendre pourquoi il pourrait exister un certain recoupement entre elles. Puis, nous exposerons l'analyse de la jurisprudence arbitrale concernant l'obligation de l'employeur d'accommoder un travailleur handicapé et celle concernant la même obligation de l'employeur envers un travailleur handicapé suite à une lésion professionnelle, afin de délimiter la compétence rationae materiae des arbitres de grief. Finalement, à la lumière d'une approche critique à la jurisprudence arbitrale analysée, nous concluons que, dans l'intérêt d'une saine administration de la justice et pour une meilleure accessibilité à un tribunal spécialisé en matière de réadaptation au travail et en matière d'évaluation de la capacité de retour au travail, il est évident que la Commission des lésions professionnelles est le tribunal le mieux placé pour trancher ces types de questions, sans pour autant enlever quoi que ce soit à la compétence de l'arbitre de grief pour se saisir de questions relatives à l'obligation d'accommodement de l'employeur.\ud ______________________________________________________________________________ \ud MOTS-CLÉS DE L’AUTEUR : obligation d'accommodement, droit à l'égalité, droit au retour au travail, compétence rationae materiae, arbitre de grief, droits fondamentaux, handicap, lésion professionnelle

A phenomenological model of cell-cell adhesion mediated by cadherins

International audienceWe present a phenomenological model intended to describe at the protein population level the formation of cell-cell junctions by the local recruitment of homophilic cadherin adhesion receptors. This modeling may have a much wider implication in biological processes since many adhesion receptors, channel proteins and other membrane-born proteins associate in clusters or oligomers at the cell surface. Mathematically, it consists in a degenerate reaction-diffusion system of two partial differential equations modeling the time-space evolution of two cadherin populations over a surface: the first one represents the diffusing cadherins and the second one concerns the fixed ones. After discussing the stability of the solutions of the model, we perform numerical simulations and show relevant analogies with experimental results. In particular, we show patterns or aggregates formation for a certain set of parameters. Moreover, perturbing the stationary solution, both density populations converge in large times to some saturation level. Finally, an exponential rate of convergence is numerically obtained and is shown to be in agreement, for a suitable set of parameters, with the one obtained in some in vitro experiments

Regulation and structure of YahD, a copper-inducible α/β serine hydrolase of Lactococcus lactis IL1403

Lactococcus lactis IL1403 is a lactic acid bacterium that is used widely for food fermentation. Copper homeostasis in this organism chiefly involves copper secretion by the CopA copper ATPase. This enzyme is under the control of the CopR transcriptional regulator. CopR not only controls its own expression and that of CopA, but also that of an additional three operons and two monocistronic genes. One of the genes under the control of CopR, yahD, encodes an α/β-hydrolase. YahD expression was induced by copper and cadmium, but not by other metals or oxidative or nitrosative stress. The three-dimensional structure of YahD was determined by X-ray crystallography to a resolution of 1.88 Å. The protein was found to adopt an α/β-hydrolase fold with the characteristic Ser-His-Asp catalytic triad. Functional testing of YahD for a wide range of substrates for esterases, lipases, epoxide hydrolases, phospholipases, amidases and proteases was, however, unsuccessful. A copper-inducible serine hydrolase has not been described previously and YahD appears to be a new functional member of this enzyme famil

Affective interactive narrative in the CALLAS Project

This full text version, available on TeesRep, is the post-print (final version prior to publication) of

The stress response protein Gls24 is induced by copper and interacts with the CopZ copper chaperone of Enterococcus hirae

Intracellular copper routing in Enterococcus hirae is accomplished by the CopZ copper chaperone. Under copper stress, CopZ donates Cu+ to the CopY repressor, thereby releasing its bound zinc and abolishing repressor-DNA interaction. This in turn induces the expression of the cop operon, which encodes CopY and CopZ, in addition to two copper ATPases, CopA and CopB. To gain further insight into the function of CopZ, the yeast two-hybrid system was used to screen for proteins interacting with the copper chaperone. This led to the identification of Gls24, a member of a family of stress response proteins. Gls24 is part of an operon containing eight genes. The operon was induced by a range of stress conditions, but most notably by copper. Gls24 was overexpressed and purified, and was shown by surface plasmon resonance analysis to also interact with CopZ in vitro. Circular dichroism measurements revealed that Gls24 is partially unstructured. The current findings establish a novel link between Gls24 and copper homeostasi

Response of gram-positive bacteria to copper stress

The Gram-positive bacteria Enterococcus hirae, Lactococcus lactis, and Bacillus subtilis have received wide attention in the study of copper homeostasis. Consequently, copper extrusion by ATPases, gene regulation by copper, and intracellular copper chaperoning are understood in some detail. This has provided profound insight into basic principles of how organisms handle copper. It also emerged that many bacterial species may not require copper for life, making copper homeostatic systems pure defense mechanisms. Structural work on copper homeostatic proteins has given insight into copper coordination and bonding and has started to give molecular insight into copper handling in biological systems. Finally, recent biochemical work has shed new light on the mechanism of copper toxicity, which may not primarily be mediated by reactive oxygen radicals

A system to support the learning of movement qualities in dance: A case study on dynamic symmetry

In this paper, we present (i) a computational model of Dynamic Symmetry of human movement, and (ii) a system to teach this movement quality (symmetry or asymmetry) by means of an interactive sonification exergame based on IMU sensors and the EyesWeb XMI software platform. The implemented system is available as a demo at the workshop