564 research outputs found

    Critical Thinking Dispositions of Pre-service Turkish Language Teachers and Primary Teachers

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    The present study aimed to determine critical thinking dispositions of pre-service Turkish language and primary teachers in terms of several variables by employing descriptive survey design. The study group consisted of 215 senior students attending Turkish Language Teaching and Primary Education Departments of Necatibey Faculty of Education at Balikesir University in the 2012-2013 academic year. The data of the study was collected with The California Critical Thinking Disposition Inventory which was adapted to Turkish by Kökdemir (2003). The scale consisting of 6 sub-scales namely analyticity, open-mindedness, inquisitiveness, self-confidence, truth-seeking and systematicity has a reliability coefficient of 0.88. Coefficients of internal consistency for each subscale range between 0.61 and 0.78. The present study found the reliability of the scale as .85. The data were analyzed through descriptive statistics, t test and one was variance analysis. It was observed in the study that the pre-service teachers had medium levels of critical thinking dispositions and that the level did not vary by their department, gender, time spent watching TV while critical thinking disposition increased as the number of books read per year went up

    The words are more than just sounds, they have the power to change the World

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    To what extent do the books and words have power on the relationships and personal development of Liesel throughout the novel “The Book Thief”

    The Effect of Acid-Reducing Pharmacotherapy on the Severity of Nausea and Vomiting of Pregnancy

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    Background. Heartburn and acid reflux (HB/RF) are associated with increased severity of nausea and vomiting. The ability of acid-reducing drugs to reduce symptoms of nausea and vomiting of pregnancy has not been previously tested. Objective. To determine whether acid-reducing pharmacotherapy decreases the severity of NVP symptoms. Methods. We studied a cohort of women experiencing NVP, who were also experiencing HB/RF. Women were counseled to commence acid-reducing pharmacotherapy. The effectiveness of the acid-reducing medication in decreasing symptoms of both HB/RF and NVP was measured. Results. Acid-reducing drugs resulted in significant decreases in PUQE (9.6 ± 3.0 to 6.5 ± 2.5, P < .0001) and well-being scores from the initial (4.0 ± 2.0) to the follow-up interview (6.8 ± 1.6, P < .0001). After intervention with acid-reducing pharmacotherapy, a reduction in acid symptoms correlated significantly with reduction in NVP (R2 = 0.72, P < .001). Conclusion. This is the first study to demonstrate that management of HB/RF can reduce the severity of NVP

    19. Yüzyılda oryantalist ressamların eserlerinde Çini Sanatı

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    06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması, Düzenlenmesi ve Erişime Açılmasına İlişkin Yönerge” gereğince tam metin erişime açılmıştır.Çini sanatı, Anadolu coğrafyasında dini, sivil mimari yapılarda iç ve dış cephelerde estetik, güzellik, ısı yalıtımı amacıyla uygulanmaktadır. Selçukludan Osmanlı dönemine kadar pek çok mimari yapıda konu, motif ve teknik açıdan zengin çini programları uygulanmıştır. Anadolu topraklarında yer alan cami, türbe gibi dini mimari eserlerinde, saray, çeşme, sebil, vapur iskeleleri, postane, tren istasyonları, belediye binaları gibi pek çok sivil yapıda çini tasarımlar görülmektedir. Çini sanatı, 19. yüzyılda Oryantalizm akımının yayılması ile Anadolu topraklarına gelen yahut bu toprakları tasavvur eden pek çok ressamın eserlerinde yer alan mimari yapıların vazgeçilmez unsurudur. Dolayısıyla Avrupalı ressamlar Anadolu'nun kültürel ve sanatsal zenginliklerini en güzel şekilde yansıtan mimari yapıların ve bu yapılarda yer alan çini bezemeli mekânların etkisinde kalmışlardır. Hazırlanan tez çalışmasında oryantalist ressamların eserlerinde görülen çini sanatının uygulandığı mekânlar ile Doğulu bir oryantalist ressam olan Osman Hamdi Bey'in eserlerindeki benzer çini detayları karşılaştırılarak Doğu ve Batı tasavvurunun ve oryantalist yaklaşımın temel özelliklerinin ortaya konulması amaçlanmıştır. Çini sanatı, oryantalist ressamların eserleriyle ilk defa oryantalizm ekseninde ele alınmaktadır. Doğulu ve Batılı ressamların oryantalizme yaklaşımı, çini sanatının kullanıldığı mekânların oryantalist resimlerde nasıl konumlandırıldığı gibi soruların cevaplandırılması hedeflenmiştir. Hazırlanan tez, 19. yüzyıldaki oryantalist ressamları, oryantalist ressamlar ile Osman Hamdi Bey'in çini detaylı resimlerini, çini sanatının oryantalizm ekseninde sorgulanmasını ve Doğu-Batı tasavvurlarını kapsamaktadır. Bu çalışmada nitel araştırma yöntemlerinden yararlanılmıştır. Kuram ve literatüre uygun olarak pek çok kitap, tez ve makale incelenerek dokümanlar toplanmış; elde edilen verilerin doküman analizi yapılmıştır. 19. yüzyıl oryantalist ressamların eserleriyle çini sanatının oryantalist resimler arasındaki yeri, nitel paradigmanın bakış açısı ile ortaya konmaya çalışılmıştır. Yapılan çalışmalar sonucunda, Batı'daki oryantalist ressamların tablolarında bulunan, 15. ve 16. yüzyıllar boyunca tasarlanmış ve üretilmiş olan çini tasarımların Osman Hamdi Bey'in resimlerinde bulunan çini tasarımlı uygulamalarla karşılaştırmaları yapılacak; benzerlikleri, farklılıkları değerlendirilecektir. Anahtar Kelimeler: Çini sanatı, 19.yy. Doğu-Batı tasavvuru, Oryantalizm, Osman Hamdi,The art of tile is applied for the purpose of aesthetics, beauty and heat insulation in the interior and exterior facades of religious and civil architectural structures in Anatolian geography. From the Seljuk to the Ottoman period, many architectural structures, motifs and techniques in rich tile programs were applied. Anatolian geography has many civil buildings such as mosques, tombs, religious buildings such as palaces, fountains, ferry ports, post office, railway stations and municipal buildings that have tile designs. Tile art is an indispensable element of the architectural structures in the works of many painters who came to Anatolia in the 19th century with the spread of Orientalism and envisaged these lands. Therefore, European painters were influenced by the architectural structures that best reflect the cultural and artistic richness of Anatolia and the tile decorated places in these buildings. In the thesis study, it is aimed to reveal the basic features of East and West concept and orientalist approach by comparing the similar tile details in the works of Osman Hamdi Bey, who is an oriental orientalist painter, with the places where the art of tile is seen in the works of orientalist painters. Orientalist painters for the first time, work with tile art, in the axis of orientalism. The approach of oriental and western painters to orientalism, how the tile art is used and placed in the orientalist paintings are aimed to be answered. The thesis included orientalist painters of the 19th century, orientalist painters and detailed paintings of Osman Hamdi Bey, the interrogation of tile art on the axis of orientalism, and the East-West conceptions. Qualitative research methods were used in this study. In accordance with the theory and literature, many books, dissertations and articles have been reviewed and documents have been collected; document analysis of the obtained data was made. The place of the art of orientalist paintings with the works of 19th century orientalist painters has been tried to be revealed with the perspective of qualitative paradigm. As a result of the studies, the designs of the tile designs, which were designed and produced during the 15th and 16th centuries in the paintings of the orientalist painters in the West, will be compared with the tile design applications in the paintings of Osman Hamdi Bey as well similarities, differences will be evaluated. Keywords: Tile art,19th century, east designation, orientalism, Osman Hamd

    Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung.

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    There is increasing interest in the potential for metabolic profiling to evaluate the progression of pulmonary hypertension (PH). However, a detailed analysis of the metabolic changes in lungs at the early stage of PH, characterized by increased pulmonary artery pressure but prior to the development of right ventricle hypertrophy and failure, is lacking in a preclinical animal model of PH. Thus, we undertook a study using rats 14 days after exposure to monocrotaline (MCT), to determine whether we could identify early stage metabolic changes prior to the manifestation of developed PH. We observed changes in multiple pathways associated with the development of PH, including activated glycolysis, increased markers of proliferation, disruptions in carnitine homeostasis, increased inflammatory and fibrosis biomarkers, and a reduction in glutathione biosynthesis. Further, our global metabolic profile data compare favorably with prior work carried out in humans with PH. We conclude that despite the MCT-model not recapitulating all the structural changes associated with humans with advanced PH, including endothelial cell proliferation and the formation of plexiform lesions, it is very similar at a metabolic level. Thus, we suggest that despite its limitations it can still serve as a useful preclinical model for the study of PH

    The effect of creative writing activities on pre-service teachers’ narrative text composing skills

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    This study aims to determine the effect of creative writing activities based on narrative expression on pre-service teachers’ ability to create narrative texts. The research was structured with a mixed research method in which qualitative and quantitative research methods were used together. Quantitatively, the study employed a pre-test post-test one-group quasi experimental design, whereas qualitatively, a case study design was employed. The sample group was composed of 20 pre-service teachers enrolled in the Turkish Language Teaching Program at a state university during the fall semester of the 2021-2022 academic year. An analytical rubric consisting of nine sections was developed for evaluating narrative texts written by pre-service teachers to collect quantitative data. A structured interview form consisting of five questions was also used to interview pre-service teachers in the study group about their opinions on the implementation process. Qualitative data were analyzed using the content analysis technique, while quantitative data were analyzed descriptively. The study concluded that narrative expression-based creative writing activities benefited Turkish pre-service teachers' abilities to create narrative text, resulting in an increase in narrative text elements. Also, creative writing activities made the story writing process enjoyable for pre-service teachers and had a positive influence on their views on the application process. The conclusion was also drawn that story elements were incorporated into narrative texts through creative writing techniques

    Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress.

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    Cellular stress responses are frequently governed by the subcellular localization of critical effector proteins. Apoptosis-inducing Factor (AIF) or Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH), for example, can translocate from mitochondria to the nucleus, where they modulate apoptotic death pathways. Hypoxia-inducible gene domain 1A (HIGD1A) is a mitochondrial protein regulated by Hypoxia-inducible Factor-1α (HIF1α). Here we show that while HIGD1A resides in mitochondria during physiological hypoxia, severe metabolic stress, such as glucose starvation coupled with hypoxia, in addition to DNA damage induced by etoposide, triggers its nuclear accumulation. We show that nuclear localization of HIGD1A overlaps with that of AIF, and is dependent on the presence of BAX and BAK. Furthermore, we show that AIF and HIGD1A physically interact. Additionally, we demonstrate that nuclear HIGD1A is a potential marker of metabolic stress in vivo, frequently observed in diverse pathological states such as myocardial infarction, hypoxic-ischemic encephalopathy (HIE), and different types of cancer. In summary, we demonstrate a novel nuclear localization of HIGD1A that is commonly observed in human disease processes in vivo
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