1,406 research outputs found
Multiresolution analysis in statistical mechanics. II. The wavelet transform as a basis for Monte Carlo simulations on lattices
In this paper, we extend our analysis of lattice systems using the wavelet
transform to systems for which exact enumeration is impractical. For such
systems, we illustrate a wavelet-accelerated Monte Carlo (WAMC) algorithm,
which hierarchically coarse-grains a lattice model by computing the probability
distribution for successively larger block spins. We demonstrate that although
the method perturbs the system by changing its Hamiltonian and by allowing
block spins to take on values not permitted for individual spins, the results
obtained agree with the analytical results in the preceding paper, and
``converge'' to exact results obtained in the absence of coarse-graining.
Additionally, we show that the decorrelation time for the WAMC is no worse than
that of Metropolis Monte Carlo (MMC), and that scaling laws can be constructed
from data performed in several short simulations to estimate the results that
would be obtained from the original simulation. Although the algorithm is not
asymptotically faster than traditional MMC, because of its hierarchical design,
the new algorithm executes several orders of magnitude faster than a full
simulation of the original problem. Consequently, the new method allows for
rapid analysis of a phase diagram, allowing computational time to be focused on
regions near phase transitions.Comment: 11 pages plus 7 figures in PNG format (downloadable separately
Coadsorption of Cinchona Alkaloids on Supported Palladium: Nonlinear Effects in Asymmetric Hydrogenation and Resistance of Alkaloids Against Hydrogenation
The transient behavior of the adsorption of cinchona alkaloid modifiers on Pd/TiO2 has been investigated in situ during the enantioselective hydrogenation of 4-methoxy-6-methyl-2-pyrone (1). Modifier mixtures consisting of pairs of alkaloids that alone afford the opposite enantiomers in comparable excess were applied to probe the adsorption behavior and possible nonlinear phenomena. Complementary information has been gathered from an indirect UV-vis study of the adsorption and hydrogenation of cinchonidine and quinidine on Pd/TiO2. The striking nonlinear behavior of cinchonidine-quinidine and cinchonine-quinine pairs in the hydrogenation of 1, and in the competitive saturation of the quinoline rings of the alkaloids, is attributed to differences in the adsorption strength and geometry of the alkaloids. The results are in good agreement with our former mechanistic model assuming that the quinoline ring of cinchona alkaloid and 1 adsorb parallel to the Pd surface during the enantiodifferentiating ste
Multiresolution analysis in statistical mechanics. I. Using wavelets to calculate thermodynamic properties
The wavelet transform, a family of orthonormal bases, is introduced as a
technique for performing multiresolution analysis in statistical mechanics. The
wavelet transform is a hierarchical technique designed to separate data sets
into sets representing local averages and local differences. Although
one-to-one transformations of data sets are possible, the advantage of the
wavelet transform is as an approximation scheme for the efficient calculation
of thermodynamic and ensemble properties. Even under the most drastic of
approximations, the resulting errors in the values obtained for average
absolute magnetization, free energy, and heat capacity are on the order of 10%,
with a corresponding computational efficiency gain of two orders of magnitude
for a system such as a Ising lattice. In addition, the errors in
the results tend toward zero in the neighborhood of fixed points, as determined
by renormalization group theory.Comment: 13 pages plus 7 figures (PNG
Deep Regionlets for Object Detection
In this paper, we propose a novel object detection framework named "Deep
Regionlets" by establishing a bridge between deep neural networks and
conventional detection schema for accurate generic object detection. Motivated
by the abilities of regionlets for modeling object deformation and multiple
aspect ratios, we incorporate regionlets into an end-to-end trainable deep
learning framework. The deep regionlets framework consists of a region
selection network and a deep regionlet learning module. Specifically, given a
detection bounding box proposal, the region selection network provides guidance
on where to select regions to learn the features from. The regionlet learning
module focuses on local feature selection and transformation to alleviate local
variations. To this end, we first realize non-rectangular region selection
within the detection framework to accommodate variations in object appearance.
Moreover, we design a "gating network" within the regionlet leaning module to
enable soft regionlet selection and pooling. The Deep Regionlets framework is
trained end-to-end without additional efforts. We perform ablation studies and
conduct extensive experiments on the PASCAL VOC and Microsoft COCO datasets.
The proposed framework outperforms state-of-the-art algorithms, such as
RetinaNet and Mask R-CNN, even without additional segmentation labels.Comment: Accepted to ECCV 201
Study of the spectral properties of ELM precursors by means of wavelets
The high confinement regime (H-mode) in tokamaks is accompanied by the occurrence of bursts of MHD activity at the plasma edge, so-called edge localized modes (ELMs), lasting less than 1 ms. These modes are often preceded by coherent oscillations in the magnetic field, the ELM precursors, whose mode numbers along the toroidal and the poloidal directions can be measured from the phase shift between Mirnov pickup coils. When the ELM precursors have a lifetime shorter than a few milliseconds, their toroidal mode number and their nonlinear evolution before the ELM crash cannot be studied reliably with standard techniques based on Fourier analysis, since averaging in time is implicit in the computation of the Fourier coefficients. This work demonstrates significant advantages in studying spectral features of the short-lived ELM precursors by using Morlet wavelets. It is shown that the wavelet analysis is suitable for the identification of the toroidal mode numbers of ELM precursors with the shortest lifetime, as well as for studying their nonlinear evolution with a time resolution comparable to the acquisition rate of the Mirnov coils
The CXCL10/CXCR3 Axis and Cardiac Inflammation: Implications for Immunotherapy to Treat Infectious and Noninfectious Diseases of the Heart.
Accumulating evidence reveals involvement of T lymphocytes and adaptive immunity in the chronic inflammation associated with infectious and noninfectious diseases of the heart, including coronary artery disease, Kawasaki disease, myocarditis, dilated cardiomyopathies, Chagas, hypertensive left ventricular (LV) hypertrophy, and nonischemic heart failure. Chemokine CXCL10 is elevated in cardiovascular diseases, along with increased cardiac infiltration of proinflammatory Th1 and cytotoxic T cells. CXCL10 is a chemoattractant for these T cells and polarizing factor for the proinflammatory phenotype. Thus, targeting the CXCL10 receptor CXCR3 is a promising therapeutic approach to treating cardiac inflammation. Due to biased signaling CXCR3 also couples to anti-inflammatory signaling and immunosuppressive regulatory T cell formation when activated by CXCL11. Numbers and functionality of regulatory T cells are reduced in patients with cardiac inflammation, supporting the utility of biased agonists or biologicals to simultaneously block the pro-inflammatory and activate the anti-inflammatory actions of CXCR3. Other immunotherapy strategies to boost regulatory T cell actions include intravenous immunoglobulin (IVIG) therapy, adoptive transfer, immunoadsorption, and low-dose interleukin-2/interleukin-2 antibody complexes. Pharmacological approaches include sphingosine 1-phosphate receptor 1 agonists and vitamin D supplementation. A combined strategy of switching CXCR3 signaling from pro- to anti-inflammatory and improving Treg functionality is predicted to synergistically lessen adverse cardiac remodeling
Construction of Parseval wavelets from redundant filter systems
We consider wavelets in L^2(R^d) which have generalized multiresolutions.
This means that the initial resolution subspace V_0 in L^2(R^d) is not singly
generated. As a result, the representation of the integer lattice Z^d
restricted to V_0 has a nontrivial multiplicity function. We show how the
corresponding analysis and synthesis for these wavelets can be understood in
terms of unitary-matrix-valued functions on a torus acting on a certain vector
bundle. Specifically, we show how the wavelet functions on R^d can be
constructed directly from the generalized wavelet filters.Comment: 34 pages, AMS-LaTeX ("amsproc" document class) v2 changes minor typos
in Sections 1 and 4, v3 adds a number of references on GMRA theory and
wavelet multiplicity analysis; v4 adds material on pages 2, 3, 5 and 10, and
two more reference
Scalar and vector modulation instabilities induced by vacuum fluctuations in fibers: numerical study
We study scalar and vector modulation instabilities induced by the vacuum
fluctuations in birefringent optical fibers. To this end, stochastic coupled
nonlinear Schrodinger equations are derived. The stochastic model is equivalent
to the quantum field operators equations and allow for dispersion,
nonlinearity, and arbitrary level of birefringence. Numerical integration of
the stochastic equations is compared to analytical formulas in the case of
scalar modulation instability and non depleted pump approximation. The effect
of classical noise and its competition with vacuum fluctuations for inducing
modulation instability is also addressed.Comment: 33 pages, 5 figure
Time scales in nuclear giant resonances
We propose a general approach to characterise fluctuations of measured cross
sections of nuclear giant resonances. Simulated cross sections are obtained
from a particular, yet representative self-energy which contains all
information about fragmentations. Using a wavelet analysis, we demonstrate the
extraction of time scales of cascading decays into configurations of different
complexity of the resonance. We argue that the spreading widths of collective
excitations in nuclei are determined by the number of fragmentations as seen in
the power spectrum. An analytic treatment of the wavelet analysis using a
Fourier expansion of the cross section confirms this principle. A simple rule
for the relative life times of states associated with hierarchies of different
complexity is given.Comment: 5 pages, 4 figure
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Conflicting vascular and metabolic impact of the IL-33/sST2 axis.
Interleukin 33 (IL-33), which is expressed by several immune cell types, endothelial and epithelial cells, and fibroblasts, is a cytokine of the IL-1 family that acts both intra- and extracellularly to either enhance or resolve the inflammatory response. Intracellular IL-33 acts in the nucleus as a regulator of transcription. Once released from cells by mechanical stress, inflammatory cytokines, or necrosis, extracellular IL-33 is proteolytically processed to act in an autocrine/paracrine manner as an 'alarmin' on neighbouring or various immune cells expressing the ST2 receptor. Thus, IL-33 may serve an important role in tissue preservation and repair in response to injury; however, the actions of IL-33 are dampened by a soluble form of ST2 (sST2) that acts as a decoy receptor and is produced by endothelial and certain immune cells. Accumulating evidence supports the conclusion that sST2 is a biomarker of vascular health with diagnostic and/or prognostic value in various cardiovascular diseases, including coronary artery disease, myocardial infarction, atherosclerosis, giant-cell arteritis, acute aortic dissection, and ischaemic stroke, as well as obesity and diabetes. Although sST2 levels are positively associated with cardiovascular disease severity, the assumption that IL-33 is always beneficial is naïve. It is increasingly appreciated that the pathophysiological importance of IL-33 is highly dependent on cellular and temporal expression. Although IL-33 is atheroprotective and may prevent obesity and type 2 diabetes by regulating lipid metabolism, IL-33 appears to drive endothelial inflammation. Here, we review the current knowledge of the IL-33/ST2/sST2 signalling network and discuss its pathophysiological and translational implications in cardiovascular diseases
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