Adrecizumab, a non-neutralizing anti-adrenomedullin antibody, improves haemodynamics and attenuates myocardial oxidative stress in septic rats

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INTERIOR DE LA BASÍLICA ANTES DE SU RESTAURACIÓN [Material gráfico]

INTERIOR DE LA IGLESIA ANTES DE SU RESTAURACIÓN. ADQUIRIDA POR EL COLECCIONISTA EN LAS PALMAS G.C.POSTAL VISTA INTERIOR DE LA IGLESIA DE TERORCopia digital. Madrid : Ministerio de Educación, Cultura y Deporte. Subdirección General de Coordinación Bibliotecaria, 201

Association between miRNA levels and hospital readmission using multivariable analyses.

<p>Odds ratios (OR) [95% confidence interval] are shown for biological parameters, including miRNAs for the risk of hospital readmission during the first year following initial presentation. ORs have been adjusted for age, gender, heart rate, systolic and diastolic blood pressure, history of atrial fibrillation and of HF, LVEF, BNP, sodium, creatinine, proteins and hemoglobin.</p

Comparison of clinical characteristics of the test and validation cohorts.

<p>Comparison of clinical characteristics of the test and validation cohorts.</p

Flow chart of the study population.

<p>Flow chart of the study population.</p

Patient characteristics of the test cohort.

<p>Patient characteristics of the test cohort.</p

Admission levels of miRNAs.

<p>Levels of 5 miRNAs were assessed in plasma samples obtained at admission in 236 AHF patients 58 non-AHF patients, and 44 CHF patients. Between-group comparisons were performed and corresponding p values are indicated.</p

MiRNA levels according to one-year outcome.

<p>MiRNA levels according to one-year outcome.</p

Prediction of death by miR-423-5p in the validation cohort.

<p>Prediction of death by miR-423-5p in the validation cohort.</p

Association between miR-423-5p levels and mortality in the validation cohort (n = 711).

<p>The cohort was divided in quartiles of miR-423-5p values and Kaplan-Meier analysis was performed with calculation of the log rank to assess statistical significance. Q denotes quartile and p values from log rank test are displayed.</p