Erythropoietin Improves Place Learning in an 8-Arm Radial Maze in Fimbria-Fornix Transected Rats

Systemically administered human recombinant erythropoietin (EPO) may have the potential to reduce the cognitive and behavioral symptoms of mechanical brain injury. In a series of studies, we address this possibility. We previously found that EPO given to fimbriafornix transected rats at the moment of injury could substantially improve the posttraumatic acquisition of an allocentric place learning task when such a task is administered in a water maze. Due to the clinical importance of such results, it is important to scrutinize whether the therapeutic effect of EPO is specific to the experimental setup of our original experiments or generalizes across test situations. Consequently, here we studied the effects of similarly administered EPO in fimbria-fornix transected and control operated rats, respectively, evaluating the posttraumatic behavioral/cognitive abilities in an allocentric place learning task administered in an 8-arm radial maze. The administration of EPO to the hippocampally injured rats was associated with a virtually complete elimination of the otherwise severe behavioral impairment caused by fimbria-fornix transection. In contrast, EPO had no detectable effect on the task acquisition of non-lesioned animals. The results of the present study confirm our previous demonstration of EPO's ability to reduce or eliminate the behavioral/cognitive consequences of mechanical injury to the hippocampus, while adding the important observation that such a therapeutic effect is not restricted to the specific experimental setup previously studied

Retirement System of the Czech Republic and alternative provision for old age

Bakalářská práce se zabývá důchodovým systémem v České Republice a porovnáním produktů k zajištění finanční nezávislosti ve stáří. Úvodní část práce je zaměřena na popis fungování systému tří pilířů s vyhodnocením jejich kladů a záporů. Další část se zaobírá alternativními možnostmi, které mohou sloužit jako doplněk ke státní penzi z důchodového pojištění. Cílem praktické části práce je na modelových příkladech prezentovat rozdíly ve výši naspořených prostředků za účelem výběru nejvhodnější alternativy a následné porovnání výše měsíční renty z těchto prostředků se státní penzí. V samotném závěru práce jsou vyhodnoceny výsledky a uvedeny další aspekty ovlivňující rozhodování účastníka.The bachelor thesis deals with the pension system in the Czech Republic and comparing products to ensure financial independence in old age. The first part focuses on the description of the functioning of the three pillars and the evaluation of the pros and cons. The next part deals with alternative options that can serve as a supplement to a state pension from the pension scheme. The aim of the practical part of the thesis is to present examples of model differences in the amount of funds saved for the purpose of selecting the best alternatives and then comparing the amount of monthly rent from these funds are state pensions. The work is concluded and the results are evaluated include other aspects influencing the decision of the participant

Taxation of income from employment in the Czech Republic and in Germany

The purpose of this master thesis is comparing the taxation of income of employees in the Czech Republic and Germany. The theoretical part is focused on describing the taxation of income of employees in both analyzed states. This part also includes an explanation of the social insurance system in both countries. The empirical part of thesis oncentrates on a comparison between the tax burden of Czech and German employees among various income groups and various taxpayer. The tax burden is then compared with the effective tax rate. The final section of this thesis compares values of redistribution indicators, such as indicators of interval and global progressivity (Lorenz curve, Gini coefficient

Development for Children who need help improving their Motor skills - Assesment and Intervention in the group of pre-school Children

This work aims to describe Dr. Kleplova's holistic programme that is intended for children who need help improving their motor skills. The first part focuses on basic theoretical knowledge and is dedicated to motor development dysfunction's manifestations and diagnostic method. The next part focuses on movement and motor skills. Third part is focused on theoretic part of Dr. Kleplova's holistic programme. In the last part I describe Dr. Kleplova's holistic programme through the practical application of some specific exercises. This part contains a case studies with medical history, some specific examinations and recommendation for exercises according to Dr. Kleplova's holistic programme

infekce, sepse, krevní řečiště

1 Abstract The aim of work: The aim of work was to provide information about the issue of bloodstream infections. Describe methods of hemocultivation techniques that are routinely used in the laboratory of the Clinical microbiology and antibiotics surveillance at Na Homolce Hospital. Give an overview of number of positive blood cultures and representation of each bacterial genus and species isolated from the blood of selected patients in the Department of Intensive care at Na Homolce Hospital in 2014 and 2015. Methods: The number of positive blood culture and the frequency representation of the various bacterial genus and species were monitoring from patients hospitalized in the Department of Vascular intensive care surgery and Intensive care unit of internal department at Na Homolce Hospital during the period from 1. 1. 2014 to 31. 12. 2015. Results: At the Vascular intensive care surgery, 537 blood cultures were collected in the time period considered. 93 blood cultures were positive from this amount, which represents 17%. The most common isolates from blood cultures were coagulase-negative staphylococci (56%), and Staphylococcus aureus (19%), the genus Candida (9%), representatives of the family Enterobacteriaceae (9%), Pseudomonas aeruginosa (3%) and members of the genus Enterococcus (2 %). At the..

Taxation of income from employment in the Czech Republic and in Germany

Cílem této diplomové práce je porovnání zdanění příjmů ze závislé činnosti v České republice a v Německu. Teoretická část práce je zaměřena na popis zdanění příjmů ze zaměstnání u sledovaných zemí včetně vysvětlení systému sociálního pojištění u obou států.Empirická část diplomové práce se zabývá porovnáním daňové zátěže příjmů ze zaměstnání u různých příjmových a typových poplatníku s použitím vhodně zvolených ukazatelů, jimiž jsou například efektivní daňová sazba. V závěrečné části práce jsou komparovány hodnoty ukazatelů redistribuce, a to intervalové a globální progresivity (Lorenzova křivka, Giniho koeficient).The purpose of this master thesis is comparing the taxation of income of employees in the Czech Republic and Germany. The theoretical part is focused on describing the taxation of income of employees in both analyzed states. This part also includes an explanation of the social insurance system in both countries. The empirical part of thesis oncentrates on a comparison between the tax burden of Czech and German employees among various income groups and various taxpayer. The tax burden is then compared with the effective tax rate. The final section of this thesis compares values of redistribution indicators, such as indicators of interval and global progressivity (Lorenz curve, Gini coefficient

Development for Children who need help improving their Motor skills

HTF - Katedra psychosociálních věd a etikyHusitská teologická fakultaHussite Theological Facult