Multipole matrix elements of Green function of Laplace equation

Multipole matrix elements of Green function of Laplace equation are calculated. The multipole matrix elements of Green function in electrostatics describe potential on a sphere which is produced by a charge distributed on the surface of a different (possibly overlapping) sphere of the same radius. The matrix elements are defined by double convolution of two spherical harmonics with the Green function of Laplace equation. The method we use relies on the fact that in the Fourier space the double convolution has simple form. Therefore we calculate the multipole matrix from its Fourier transform. An important part of our considerations is simplification of the three dimensional Fourier transformation of general multipole matrix by its rotational symmetry to the one-dimensional Hankel transformation

The benthic-pelagic coupling affects the surface water carbonate system above groundwater-charged coastal sediments

Submarine groundwater discharge (SGD) can be a significant source of dissolved nutrients, inorganic and organic carbon, and trace metals in the ocean and therefore can be a driver for the benthic-pelagic coupling. However, the influence of hypoxic or anoxic SGD on the carbonate system of coastal seawater is still poorly understood. In the present study, the production of dissolved inorganic carbon (DIC) and alkalinity (AT) in coastal sediments has been investigated under the impact of oxygen-deficient SGD and was estimated based on the offset between the measured data and the conservative mixing of the end members. Production of AT and DIC was primarily caused by denitrification and sulphate reduction. The AT and DIC concentrations in SGD decreased by approximately 32% and 37% mainly due to mixing with seawater counterbalanced by reoxidation and CO2 release into the atmosphere. Total SGD-AT and SGD-DIC fluxes ranged from 0.1 to 0.2mol m-2 d-1 and from 0.2 to 0.3mol m-2 d-1, respectively. These fluxes are probably the reason why the seawater in the Bay of Puck is enriched in AT and DIC compared to the open waters of the Baltic Sea. Additionally, SGD had low pH and was undersaturated with respect to the forms of the aragonite and calcite minerals of CaCO3. The seawater of the Bay of Puck also turned out to be undersaturated in summer (Inner Bay) and fall (Outer Bay). We hypoth​e​size that SGD can potentially contribute to ocean acidification and affect the functioning of the calcifying invertebrates

The correlation of mutations and expressions of genes within the PI3K/Akt/mTOR pathway in breast cancer : a preliminary study

There is an urgent need to seek new molecular biomarkers helpful in diagnosing and treating breast cancer. In this elaboration, we performed a molecular analysis of mutations and expression of genes within the PI3K/Akt/mTOR pathway in patients with ductal breast cancer of various malignancy levels. We recognized significant correlations between the expression levels of the studied genes. We also performed a bioinformatics analysis of the data available on the international database TCGA and compared them with our own research. Studies on mutations and expression of genes were conducted using High-Resolution Melt PCR (HRM-PCR), Allele-Specific-quantitative PCR (ASP-qPCR), Real-Time PCR molecular methods in a group of women with ductal breast cancer. Bioinformatics analysis was carried out using web source Ualcan and bc-GenExMiner. In the studied group of women, it was observed that the prevalence of mutations in the studied PIK3CA and AKT1 genes was 29.63%. It was stated that the average expression level of the PIK3CA, PIK3R1, PTEN genes in the group of breast cancer patients is lower in comparison to the control group, while the average expression level of the AKT1 and mTOR genes in the studied group was higher in comparison to the control group. It was also indicated that in the group of patients with mutations in the area of the PIK3CA and AKT1 genes, the PIK3CA gene expression level is statistically significantly lower than in the group without mutations. According to our knowledge, we demonstrate, for the first time, that there is a very strong positive correlation between the levels of AKT1 and mTOR gene expression in the case of patients with mutations and without mutations

Kultura i społeczeństwo na Środkowym Nadodrzu w XIX i XX wieku

303 s. : il., portr.

Experimental study of smog microphysical and optical vertical structure in the Silesian Beskids, Poland

This study presents the vertical profiles of aerosol optical and microphysical properties obtained from cable car and ground-based measurements in the Silesian Beskids, Poland. The data were collected during a measurement campaign between 25 February and March 11, 2018. An AE-51 micro-aethalometer and PMS7003 and OPC-N2 optical particle counters were mounted on the cable car and used to measure the profiles of equivalent of black carbon (eBC) concentration and aerosol size distribution. In situ measurements of the optical properties of the aerosols were obtained using an AE-31 aethalometer and photoacoustic devices. A prototype lidar was used to determine the planetary boundary layer (PBL) height and the aerosol layers. In the middle phase of the study (1–6 March 2018), significant night-time temperature inversions were observed. During the inversion period, the parameters describing the amount of aerosols in the air increased significantly. The concentration of eBC exceeded the level of 15 μg/m3 several times, with an average level of 5.39 ± 4.42 μg/m3. Conversely, the results obtained in the first and third phases of the experiment were at the level of the aerosol background, being 1.45 ± 0.88 μg/m3 and 0.90 ± 0.95 μg/m3, respectively. Significant differences were also observed in the vertical profiles of PM10 mass and eBC concentration. In the middle phase of the study, the profiles showed a significant reduction in the concentration of pollutants with height, while in the first and third phases, there were slight variations with height

Comparison of meteorological conditions in Svalbard fjords: Hornsund and Kongsfjorden

This paper presents the results of a comparison of basic meteorological parameters in two Arctic fjords situated on the west coast of Spitsbergen, the main island of the Svalbard archipelago. Air temperature, wind speed and direction, humidity and cloud cover from the period 2005 to 2016 are described and compared with previous (from 1975) analyses of meteorological conditions in the investigated region. Such a choice of dates coincides with the time the GAME project measurements were carried out. The main goal of this study was to compare meteorological conditions in two fjords: Hornsund and Kongsfjorden, during the time of rapid climate changes. The results are collated with research results available in literature from previous years. We discovered that in the investigated period the climate of the Hornsund region is more oceanic than in Kongsfjorden. The stable level of the difference in climate elements is manifested and is evident mainly through greater amplitudes in air temperatures in Kongsfjorden, and in stronger winds in Hornsund

Optical and radiative properties of an aerosol over South-Eastern Poland emitted during biomass burning in California in September 2020

Celem pracy jest określenie własności optycznych i radiacyjnych aerozolu obserwowanego podczas transportu dalekiego zasięgu zanieczyszczeń wyemitowanych w Ameryce Północnej we wrześniu 2020 r. Badania zostały zrealizowane w oparciu o dane pomiarowe pozyskane z fotometru słonecznego, lidaru oraz radiometru słonecznego (pyranometru) w stacji badawczej SolarAOT w Strzyżowie na Podkarpaciu, a także w oparciu o wyniki symulacji modelem trajektorii wstecznych, modelem transferu radiacji i transportu zanieczyszczeń. Wyniki badań wskazują na obecność silnie rozpraszających warstw aerozolu w całej troposferze oraz w dolnej stratosferze (pod koniec okresu pomiarowego). Obecność aerozolu w dolnej stratosferze jest w ostatnich latach bardzo rzadko obserwowana. Mimo tego wartości aerozolowej grubości optycznej były poniżej średniej wieloletniej. Obecność aerozolu w atmosferze spowodowała redukcję promieniowania dochodzącego do powierzchni ziemi w godzinach południowych o około 32 W/m2. Wymuszanie radiacyjne aerozolu podczas bezchmurnych warunków wynosiło ok -9 W/m2 na powierzchni ziemi i -5,2 W/m2 na górnej granicy atmosfery. Oszacowane wartości efektywności wymuszania radiacyjnego w połączeniu z pomiarami albedo pojedynczego rozpraszania wskazują na napływ umiarkowanie absorbującego aerozolu.The aim of the study is to determine the optical and radiation properties of the aerosol observed during long-range transport of biomass burning pollution emitted in North America in September 2020. The research was carried out at SolarAOT research station in Strzyzow (south-eastern Poland) on the basis of measurement data obtained from a sun photometer, aerosol lidar and solar radiometer (pyranometer), as well as on the basis of simulation results with backtrajetories model, radiation transfer and aerosol transport model. The results indicate the presence of highly scattering aerosol layers throughout the troposphere and in the lower stratosphere (during the end of the measuring period). The presence of an aerosol in the lower stratosphere has been very rarely observed in recent years due low stratovolcanic activity. Despite this, the aerosol optical thickness was below the long-term average. The presence of the aerosol in the atmosphere reduced the radiation reaching the Earth’s surface at noon by about 32 W/m2. The aerosol direct radiative forcing of the during clear conditions was about -9 W/m2 at the Earth’s surface and -5.2 W/m2 at the top of the atmosphere. The estimated radiative forcing efficiency in combination with the single scattering albedo measurements indicate moderately absorbing particles

The BIRC family genes expression in patients with triple negative breast cancer

The BIRC (baculoviral IAP repeat-containing; BIRC) family genes encode for Inhibitor of Apoptosis (IAP) proteins. The dysregulation of the expression levels of the genes in question in cancer tissue as compared to normal tissue suggests that the apoptosis process in cancer cells was disturbed, which may be associated with the development and chemoresistance of triple negative breast cancer (TNBC). In our study, we determined the expression level of eight genes from the BIRC family using the Real-Time PCR method in patients with TNBC and compared the obtained results with clinical data. Additionally, using bioinformatics tools (Ualcan and The Breast Cancer Gene-Expression Miner v4.5 (bc-GenExMiner v4.5)), we compared our data with the data in the Cancer Genome Atlas (TCGA) database. We observed diverse expression pattern among the studied genes in breast cancer tissue. Comparing the expression level of the studied genes with the clinical data, we found that in patients diagnosed with breast cancer under the age of 50, the expression levels of all studied genes were higher compared to patients diagnosed after the age of 50. We observed that in patients with invasion of neoplastic cells into lymphatic vessels and fat tissue, the expression levels of BIRC family genes were lower compared to patients in whom these features were not noted. Statistically significant differences in gene expression were also noted in patients classified into three groups depending on the basis of the Scarff-Bloom and Richardson (SBR) Grading System

Studies of vertical coarse aerosol fluxes in the boundary layer over the Baltic Sea* This work was supported through the National Science Centre grant NN 306315536; support for this study was also provided by the project ‘Satellite Monitoring of the Baltic Sea Environment – SatBałtyk’ funded by European Union through European Regional Development Fund contract No. POIG 01.01.02-22-011/09.

The results of studies of the vertical gradient of aerosol concentration measurements made during cruises of r/v ‘Oceania’ between 2008 and 2012 are presented. Using the results from those experiments, sea spray emission fluxes were calculated for all particles of sizes in the range from 0.5 μm to 8 μm, as well as for particles of sizes from fifteen channels of 0.5 μm width. The information obtained was further used to calculate the Sea Salt Generation Function (SSGF) for the Baltic Sea depending on the wind speed and the aerosol size distribution

Aerosol physical properties in Spitsbergen's fjords: Hornsund and Kongsfjorden during AREX campaigns in 2014 and 2015

We present results of measurements of aerosol physical properties conducted on board of r/v Oceania during two cruises to the Spitsbergen region in 2014 (AREX 2014) and 2015 (AREX 2015). Measurements of aerosol size distribution, aerosol scattering coefficient and black carbon concentrations were made in two different Spitsbergen fjords: Hornsund and Kongsfjorden. The aerosol size distribution was measured in the size range from 0.09 μm to 47 μm using two aerosol size distribution spectrometers and a standard condensation particle counter. For the scattering coefficient an integrating nephelometer was used. Black carbon concentration was measured by an aethalometer. Temporal variabilities in physical properties of aerosol observed during the AREX 2014 and AREX 2015 campaigns were much higher than the differences between both fjords. The basic factors influencing aerosol conditions were advection and local generation of marine aerosol. In 2015 an episode of smoke advection was observed in both fjords causing an increase in the mean black carbon concentration from 7–12 ng m−3 to about 60 ng m−3, and an aerosol scattering coefficient at 550 nm from 2–4 Mm−1 to 12–17 Mm−1. Moreover, under certain conditions statistically significant gradients in aerosol optical properties were observed along the fjord axis reflecting an impact of mountains surrounding the fjords